FERMA548734
TRBC1 Monoclonal Antibody (5D9F1), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FERMA548734-Each-of-1 | In Stock | ₹ 41,881.62 |
FERMA548734 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,881.62
GST (18%): ₹ 7,538.692
Total Price: ₹ 49,420.312
Antigen
TRBC1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
P01850
Gene Symbols
TRBC1
Immunogen
Purified recombinant fragment of human TRBC1 (AA: 1-149) expressed in E. Coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
5D9F1
Conjugate
Unconjugated
Gene
TRBC1
Gene Alias
BV05S1J2.2; T cell receptor beta constant 1; TCRB; TCRBC1; TRBC1
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
28639
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG1
Related Products
Description
- Constant region of T cell receptor (TR) alpha chain (PubMed:24600447)
- Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes
- Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333)
- Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70
- In turn, ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome
- The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:9382891, PubMed:23524462)
- The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement
- This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells
- Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585)
- [UniProt]
Compare Similar Items
Show Difference
Antigen: TRBC1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: P01850
Gene Symbols: TRBC1
Immunogen: Purified recombinant fragment of human TRBC1 (AA: 1-149) expressed in E. Coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 5D9F1
Conjugate: Unconjugated
Gene: TRBC1
Gene Alias: BV05S1J2.2; T cell receptor beta constant 1; TCRB; TCRBC1; TRBC1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 28639
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG1
Antigen:
TRBC1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
P01850
Gene Symbols:
TRBC1
Immunogen:
Purified recombinant fragment of human TRBC1 (AA: 1-149) expressed in E. Coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
5D9F1
Conjugate:
Unconjugated
Gene:
TRBC1
Gene Alias:
BV05S1J2.2; T cell receptor beta constant 1; TCRB; TCRBC1; TRBC1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
28639
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG1
Antigen: TRIB2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: Q92519
Gene Symbols: Trib2
Immunogen: Purified recombinant fragment of human TRIB2 (AA: 1-200) expressed in E. Coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone: 6A12A12B1
Conjugate: Unconjugated
Gene: Trib2
Gene Alias: AW319517; C5FW; GS3955; RGD1564451; TRB2; TRB-2; trib2; TRIB2 (HGNC:30809); Tribbles homolog 2; tribbles homolog 2 (Drosophila); tribbles pseudokinase 2
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 28951
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG2a
Antigen:
TRIB2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
Q92519
Gene Symbols:
Trib2
Immunogen:
Purified recombinant fragment of human TRIB2 (AA: 1-200) expressed in E. Coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone:
6A12A12B1
Conjugate:
Unconjugated
Gene:
Trib2
Gene Alias:
AW319517; C5FW; GS3955; RGD1564451; TRB2; TRB-2; trib2; TRIB2 (HGNC:30809); Tribbles homolog 2; tribbles homolog 2 (Drosophila); tribbles pseudokinase 2
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
28951
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG2a
Antigen: PYCARD
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: Q9ULZ3
Gene Symbols: PYCARD
Immunogen: Purified recombinant fragment of human PYCARD (AA: 1-120) expressed in E. Coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 1C3D3
Conjugate: Unconjugated
Gene: PYCARD
Gene Alias: 9130417A21Rik; Apoptosis-associated speck-like protein containing a CARD; Asc; CARD5; caspase recruitment domain-containing protein 5; hASC; mASC; MGC10332; Pycard; PYD and CARD domain containing; PYD and CARD domain-containing protein; Target of methylation-induced silencing 1; TMS; TMS1; TMS-1; TNS1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 29108
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG1
Antigen:
PYCARD
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
Q9ULZ3
Gene Symbols:
PYCARD
Immunogen:
Purified recombinant fragment of human PYCARD (AA: 1-120) expressed in E. Coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
1C3D3
Conjugate:
Unconjugated
Gene:
PYCARD
Gene Alias:
9130417A21Rik; Apoptosis-associated speck-like protein containing a CARD; Asc; CARD5; caspase recruitment domain-containing protein 5; hASC; mASC; MGC10332; Pycard; PYD and CARD domain containing; PYD and CARD domain-containing protein; Target of methylation-induced silencing 1; TMS; TMS1; TMS-1; TNS1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
29108
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG1
Antigen: CLEC4A
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: Q9UMR7
Gene Symbols: CLEC4A
Immunogen: Purified recombinant fragment of human CD367 (AA: extra 70-237) expressed in E. Coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry, Western Blot
Clone: 1B4A10
Conjugate: Unconjugated
Gene: CLEC4A
Gene Alias: CD367; CLEC4A; Clec4a2; Clecsf6; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 6; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 6; C-type lectin DDB27; C-type lectin domain family 4 member A; C-type lectin domain family 4, member A; C-type lectin domain family 4, member a2; C-type lectin superfamily member 6; DCIR; Dcir1; Dcir2; DDB27; Dendritic cell immunoreceptor; dendritic cell inhibitory receptor 1; dendritic cell inhibitory receptor 2; HDCGC13P; immunoreceptor; lectin-like immunoreceptor; LLIR
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 50856
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG2a
Antigen:
CLEC4A
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
Q9UMR7
Gene Symbols:
CLEC4A
Immunogen:
Purified recombinant fragment of human CD367 (AA: extra 70-237) expressed in E. Coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Western Blot
Clone:
1B4A10
Conjugate:
Unconjugated
Gene:
CLEC4A
Gene Alias:
CD367; CLEC4A; Clec4a2; Clecsf6; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 6; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 6; C-type lectin DDB27; C-type lectin domain family 4 member A; C-type lectin domain family 4, member A; C-type lectin domain family 4, member a2; C-type lectin superfamily member 6; DCIR; Dcir1; Dcir2; DDB27; Dendritic cell immunoreceptor; dendritic cell inhibitory receptor 1; dendritic cell inhibitory receptor 2; HDCGC13P; immunoreceptor; lectin-like immunoreceptor; LLIR
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
50856
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG2a