FERMA548805
SIRP alpha Monoclonal Antibody (2H7E2), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FERMA548805-Each-of-1 | In Stock | ₹ 41,881.62 |
FERMA548805 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,881.62
GST (18%): ₹ 7,538.692
Total Price: ₹ 49,420.312
Antigen
SIRP alpha
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
P78324
Gene Symbols
SIRPA
Immunogen
Purified recombinant fragment of human CD172A (AA: extra 235-373) expressed in E. Coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Flow Cytometry, Western Blot
Clone
2H7E2
Conjugate
Unconjugated
Gene
SIRPA
Gene Alias
AI835480; Bit; brain Ig-like molecule with tyrosine-based activation motifs; Brain immunoglobulin like protein with tyrosine - based activation motifs; brain immunological-like with tyrosine-based motifs; brain-immunoglobulin-like molecule with tyrosine-based activation motifs; CD172; CD172 alpha; CD172 antigen-like family member A; CD172A; Inhibitory receptor SHPS-1; macrophage fusion receptor; Macrophage membrane protein MFP150; MFR; mSIRP-alpha1; Myd1; MYD-1; myD-1 antigen; p84; Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1); protein tyrosine phosphatase, non-receptor type substrate 1; Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1); Ptpns1; SHP substrate 1; SHP-1; SHPS1; SHPS-1; signal regulatory protein alpha; signal-regulatory protein alpha; signal-regulatory protein alpha-1; Signal-regulatory protein alpha-2; Signal-regulatory protein alpha-3; SIRP; Sirpa; SIRPalpha; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3; swc3; swine workshop cluster 3 antigen; swine workshop cluster 3 antigen precursor; tyrosine phosphatase SHP substrate 1; tyrosine-protein phosphatase non-receptor type substrate 1
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
140885
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG1
Related Products
Description
- SIRP alpha (CD172a, signal-regulatory protein alpha) is a receptor-type transmembrane glycoprotein expressed on cells of myeloid origin, including granulocytes, dendritic cells (DCs), macrophages, mast cells and hematopoietic stem cells
- SIRP alpha acts as a substrate for several activated tyrosine kinases, including EGFR, PDGFR, src and insulin receptor and is involved in the negative regulation of receptor tyrosine kinase-coupled signaling pathways
- The ligand binding of SIRP alpha to integrin-associated protein CD47 results in tyrosine kinase phosphorylation of immunoreceptor tyrosine-based inhibitory motifs (ITIMs) within the cytoplasmic region of SIRP alpha, which mediates the recruitment and activation of the tyrosine phosphatases SHP-1 and SHP-2
- Ligation of SIRP alpha with CD47 has been demonstrated in several regulatory processes, including the inhibition of host cell phagocytosis by macrophages and the bi-directional activation of T cells and DCs
- SIRP alpha has regulatory effects on cellular responses induced by serum, growth factors, insulin, oncogenes, growth hormones and cell adhesion, and plays a general role in different physiological and pathological processes
- Cancer cells highly express CD47, which activates SIRP alpha and inhibits macrophage-mediated destruction of cancerous cell growth.
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Antigen: SIRP alpha
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: P78324
Gene Symbols: SIRPA
Immunogen: Purified recombinant fragment of human CD172A (AA: extra 235-373) expressed in E. Coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry, Western Blot
Clone: 2H7E2
Conjugate: Unconjugated
Gene: SIRPA
Gene Alias: AI835480; Bit; brain Ig-like molecule with tyrosine-based activation motifs; Brain immunoglobulin like protein with tyrosine - based activation motifs; brain immunological-like with tyrosine-based motifs; brain-immunoglobulin-like molecule with tyrosine-based activation motifs; CD172; CD172 alpha; CD172 antigen-like family member A; CD172A; Inhibitory receptor SHPS-1; macrophage fusion receptor; Macrophage membrane protein MFP150; MFR; mSIRP-alpha1; Myd1; MYD-1; myD-1 antigen; p84; Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1); protein tyrosine phosphatase, non-receptor type substrate 1; Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1); Ptpns1; SHP substrate 1; SHP-1; SHPS1; SHPS-1; signal regulatory protein alpha; signal-regulatory protein alpha; signal-regulatory protein alpha-1; Signal-regulatory protein alpha-2; Signal-regulatory protein alpha-3; SIRP; Sirpa; SIRPalpha; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3; swc3; swine workshop cluster 3 antigen; swine workshop cluster 3 antigen precursor; tyrosine phosphatase SHP substrate 1; tyrosine-protein phosphatase non-receptor type substrate 1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 140885
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG1
Antigen:
SIRP alpha
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
P78324
Gene Symbols:
SIRPA
Immunogen:
Purified recombinant fragment of human CD172A (AA: extra 235-373) expressed in E. Coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Western Blot
Clone:
2H7E2
Conjugate:
Unconjugated
Gene:
SIRPA
Gene Alias:
AI835480; Bit; brain Ig-like molecule with tyrosine-based activation motifs; Brain immunoglobulin like protein with tyrosine - based activation motifs; brain immunological-like with tyrosine-based motifs; brain-immunoglobulin-like molecule with tyrosine-based activation motifs; CD172; CD172 alpha; CD172 antigen-like family member A; CD172A; Inhibitory receptor SHPS-1; macrophage fusion receptor; Macrophage membrane protein MFP150; MFR; mSIRP-alpha1; Myd1; MYD-1; myD-1 antigen; p84; Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1); protein tyrosine phosphatase, non-receptor type substrate 1; Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1); Ptpns1; SHP substrate 1; SHP-1; SHPS1; SHPS-1; signal regulatory protein alpha; signal-regulatory protein alpha; signal-regulatory protein alpha-1; Signal-regulatory protein alpha-2; Signal-regulatory protein alpha-3; SIRP; Sirpa; SIRPalpha; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3; swc3; swine workshop cluster 3 antigen; swine workshop cluster 3 antigen precursor; tyrosine phosphatase SHP substrate 1; tyrosine-protein phosphatase non-receptor type substrate 1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
140885
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG1
Antigen: CD300f
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: Q8TDQ1
Gene Symbols: CD300LF
Immunogen: Purified recombinant fragment of human CD300F (AA: Extra(20-156)) expressed in E. Coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone: 2F1E11
Conjugate: Unconjugated
Gene: CD300LF
Gene Alias: CD300 antigen like family member F; CD300 antigen-like family member F; CD300 molecule like family member f; CD300 molecule-like family member f; CD300f; Cd300lf; CLIM1; CLM1; CLM-1; CMRF-35-like molecule 1; CMRF35-like molecule 1; DC-derived Ig-like receptor 2; Digr2; F730004D16Rik; IgSF13; Immune receptor expressed on myeloid cells 1; immunoglobin superfamily member 13; immunoglobulin superfamily member 13; inhibitory receptor IREM1; IREM1; IREM-1; Leukocyte mono-Ig-like receptor 3; Lmir3; MAIR-5; MAIR-V; myeloid-associated immunoglobulin-like receptor 5; NK inhibitory receptor; NKIR; Pigr3; UNQ3105/PRO10111
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 146722
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG2b
Antigen:
CD300f
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
Q8TDQ1
Gene Symbols:
CD300LF
Immunogen:
Purified recombinant fragment of human CD300F (AA: Extra(20-156)) expressed in E. Coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone:
2F1E11
Conjugate:
Unconjugated
Gene:
CD300LF
Gene Alias:
CD300 antigen like family member F; CD300 antigen-like family member F; CD300 molecule like family member f; CD300 molecule-like family member f; CD300f; Cd300lf; CLIM1; CLM1; CLM-1; CMRF-35-like molecule 1; CMRF35-like molecule 1; DC-derived Ig-like receptor 2; Digr2; F730004D16Rik; IgSF13; Immune receptor expressed on myeloid cells 1; immunoglobin superfamily member 13; immunoglobulin superfamily member 13; inhibitory receptor IREM1; IREM1; IREM-1; Leukocyte mono-Ig-like receptor 3; Lmir3; MAIR-5; MAIR-V; myeloid-associated immunoglobulin-like receptor 5; NK inhibitory receptor; NKIR; Pigr3; UNQ3105/PRO10111
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
146722
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG2b
Antigen: CLEC12A
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: Q5QGZ9
Gene Symbols: CLEC12A
Immunogen: Purified recombinant fragment of human CLL1 (AA: extra 65-265) expressed in E. Coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry, Western Blot
Clone: 6B3G8
Conjugate: Unconjugated
Gene: CLEC12A
Gene Alias: CD371; Clec12a; CLL1; CLL-1; C-type lectin domain family 12 member A; C-type lectin domain family 12, member A; C-type lectin protein CLL-1; C-type lectin-like molecule 1; C-type lectin-like molecule-1; D230024O04; DCAL2; DCAL-2; Dendritic cell-associated lectin 2; KLRL1; Micl; Myeloid inhibitory C-type lectin-like receptor
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 160364
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG1
Antigen:
CLEC12A
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
Q5QGZ9
Gene Symbols:
CLEC12A
Immunogen:
Purified recombinant fragment of human CLL1 (AA: extra 65-265) expressed in E. Coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Western Blot
Clone:
6B3G8
Conjugate:
Unconjugated
Gene:
CLEC12A
Gene Alias:
CD371; Clec12a; CLL1; CLL-1; C-type lectin domain family 12 member A; C-type lectin domain family 12, member A; C-type lectin protein CLL-1; C-type lectin-like molecule 1; C-type lectin-like molecule-1; D230024O04; DCAL2; DCAL-2; Dendritic cell-associated lectin 2; KLRL1; Micl; Myeloid inhibitory C-type lectin-like receptor
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
160364
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG1
Antigen: PI16
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: Q6UXB8
Gene Symbols: PI16
Immunogen: Purified recombinant fragment of human CD364 (AA: 79-210) expressed in E. Coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry, Western Blot
Clone: 5D4C7
Conjugate: Unconjugated
Gene: PI16
Gene Alias: 1200009H11Rik; CD364; Cripi; CRISP9; CRISP-9; Cysteine-rich protease inhibitor; cysteine-rich secretory protein 9; microseminoprotein, beta-binding protein; MSMBBP; peptidase inhibitor 16; Pi16; PI-16; protease inhibitor 16; PSEC0164; PSP94-binding protein; PSPBP; UNQ289/PRO328
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 221476
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG1
Antigen:
PI16
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
Q6UXB8
Gene Symbols:
PI16
Immunogen:
Purified recombinant fragment of human CD364 (AA: 79-210) expressed in E. Coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Western Blot
Clone:
5D4C7
Conjugate:
Unconjugated
Gene:
PI16
Gene Alias:
1200009H11Rik; CD364; Cripi; CRISP9; CRISP-9; Cysteine-rich protease inhibitor; cysteine-rich secretory protein 9; microseminoprotein, beta-binding protein; MSMBBP; peptidase inhibitor 16; Pi16; PI-16; protease inhibitor 16; PSEC0164; PSP94-binding protein; PSPBP; UNQ289/PRO328
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
221476
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG1