FERMA549001

Complement C9 Monoclonal Antibody (C9-6-25-5), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FERMA549001-Each-of-1 In Stock ₹ 49,410.90

FERMA549001 - Each of 1

₹ 49,410.90

In Stock

Quantity

1

Base Price: ₹ 49,410.90

GST (18%): ₹ 8,893.962

Total Price: ₹ 58,304.862

Antigen

Complement C9

Classification

Monoclonal

Concentration

100 μg/mL

Formulation

PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.

P06683

Gene Symbols

C9

Immunogen

Murine C9 peptide

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Form

Liquid

Applications

Western Blot

Clone

C9-6-25-5

Conjugate

Unconjugated

Gene

C9

Gene Alias

ARMD15; C9; C9D; complement C9; complement component 9; complement component C9; Complement component C9a; Complement component C9b; complement protein C9; complement protein C9 precursor

Host Species

Rat

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

12279

Content And Storage

4° C

Isotype

IgG2a

Related Products

Img

Thermo Scientific

FERMA549000

--

Img

Thermo Scientific

FERMA548998

--

Img

Thermo Scientific

FERMA548997

--

Img

Thermo Scientific

FERMA549003

--

Img

Thermo Scientific

FERMA548994

--

Img

Thermo Scientific

FERMA548991

--

Img

Thermo Scientific

FERMA549027

--

Img

Thermo Scientific

FERMA549026

--

Description

  • C5b-9 membrane attack complexes are assembled from five precursor molecules in the serum
  • Proteolytic cleavage of C5 by C5 convertase generates C5b which initiates assembly of the C5b-9 complex
  • The last step of C5b-9 complex formation involves polymerization of C9 which accompanies insertion of the complex into the cell membrane
  • During formation of C5b-8 and C9 polymerization, neoantigens are generated which are unique to the C5b-9 complex and are not present on any of the individual native complex components
  • The complement regulatory proteins CD59 and complement S-protein can both prevent C5b-9 insertion into the cell membrane
  • The formed SC5b-9 complex is unable to attach to cells and is cytolytically inactive
  • C5b-9 is involved in the progression of chronic proteinuric renal disease by mediating continuous tubulointerstitial damage
  • Early tubulointerstitial injury in the remnant kidney can be improved when C5b-9 complex forming is abrogated.

Compare Similar Items

Show Difference

Img

Thermo Scientific

FERMA549001

--


Antigen:
Complement C9

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.:
P06683

Gene Symbols:
C9

Immunogen:
Murine C9 peptide

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
Western Blot

Clone:
C9-6-25-5

Conjugate:
Unconjugated

Gene:
C9

Gene Alias:
ARMD15; C9; C9D; complement C9; complement component 9; complement component C9; Complement component C9a; Complement component C9b; complement protein C9; complement protein C9 precursor

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
12279

Content And Storage:
4° C

Isotype:
IgG2a

Img

Thermo Scientific

FERMA549003

--


Antigen:
C9 Neoantigen

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
The monoclonal antibody WU13-15 recognizes a neoepitope on the 61 kDa complement component C9, integrated in the terminal complement complex (TCC).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Inhibition Assays, Western Blot

Clone:
WU13-15

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
C9

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C

Isotype:
IgG1

Img

Thermo Scientific

FERMA549004

--


Antigen:
MCP-1

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.:
P10148

Gene Symbols:
Ccl2

Immunogen:
Synthetic peptide corresponding to residues 102-130 of mouse MCP-1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
Immunohistochemistry (Frozen), Western Blot

Clone:
ECE.2

Conjugate:
Unconjugated

Gene:
Ccl2

Gene Alias:
Acidic seminal fluid protein; AI323594; C-C motif chemokine 2; C-C motif chemokine ligand 2; Ccl2; chemokine (C-C motif) ligand 2; GDCF-2; HC11; H-MCP-1; HSMCR30; immediate-early serum-responsive JE protein; immediate-early serum-responsive protein JE; Je; MCAF; Mcp1; MCP-1; MCP1A; MCP-1A; MGC9434; Monocyte chemoattractant protein 1; monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; monocyte chemotactic protein 1A; Monocyte secretory protein JE; monocyte-chemoattractant protein-1 precursor; platelet-derived growth factor-inducible protein JE; RP23-350G1.3; SCYA2; Sigje; small inducible cytokine A2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); small inducible cytokine subfamily A (Cys-Cys), member 2; small inducible gene JE; small-inducible cytokine A2; SMC-CF

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
20296

Content And Storage:
4° C

Isotype:
IgG1

Img

Thermo Scientific

FERMA549005

--


Antigen:
MCP-1

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.:
P10148

Gene Symbols:
Ccl2

Immunogen:
Synthetic peptide corresponding to residues 102-130 of mouse MCP-1

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
Immunohistochemistry (Frozen), Western Blot

Clone:
ECE.2

Conjugate:
Biotin

Gene:
Ccl2

Gene Alias:
Acidic seminal fluid protein; AI323594; C-C motif chemokine 2; C-C motif chemokine ligand 2; Ccl2; chemokine (C-C motif) ligand 2; GDCF-2; HC11; H-MCP-1; HSMCR30; immediate-early serum-responsive JE protein; immediate-early serum-responsive protein JE; Je; MCAF; Mcp1; MCP-1; MCP1A; MCP-1A; MGC9434; Monocyte chemoattractant protein 1; monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; monocyte chemotactic protein 1A; Monocyte secretory protein JE; monocyte-chemoattractant protein-1 precursor; platelet-derived growth factor-inducible protein JE; RP23-350G1.3; SCYA2; Sigje; small inducible cytokine A2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); small inducible cytokine subfamily A (Cys-Cys), member 2; small inducible gene JE; small-inducible cytokine A2; SMC-CF

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
20296

Content And Storage:
4° C

Isotype:
IgG1