FERMA549095

PR3 Monoclonal Antibody (WGM2), FITC, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FERMA549095-Each-of-1 In Stock ₹ 76,918.44

FERMA549095 - Each of 1

₹ 76,918.44

In Stock

Quantity

1

Base Price: ₹ 76,918.44

GST (18%): ₹ 13,845.319

Total Price: ₹ 90,763.759

Antigen

PR3

Classification

Monoclonal

Concentration

100 μg/mL

Formulation

PBS with 1% BSA and 0.02% sodium azide

Gene Accession No.

P24158

Gene Symbols

PRTN3

Immunogen

Monoclonal antibody WGM2 reacts with human proteinase 3 (PR3), a 30 kDa protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Inhibition Assays, Western Blot

Clone

WGM2

Conjugate

FITC

Gene

PRTN3

Gene Alias

ACPA; AGP7; azurophil granule protein 7; CANCA; C-ANCA; C-ANCA antigen; leukocyte proteinase 3; MBN; MBT; mPR3; Myeloblastin; neutrophil proteinase 4; NP4; NP-4; P29; PR3; PR-3; Proteinase 3; PRTN3; serine proteinase, neutrophil; wegener autoantigen; Wegener granulomatosis autoantigen

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

5657

Content And Storage

4° C, store in dark

Isotype

IgG1

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Description

  • Monoclonal antibody WGM2 blocks the PR3 activity and partially inhibits the binding of human PR3-ANCA to PR3
  • Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246)
  • By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369)
  • May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279)
  • [UniProt]

Compare Similar Items

Show Difference

Img

Thermo Scientific

FERMA549095

--


Antigen:
PR3

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 1% BSA and 0.02% sodium azide

Gene Accession No.:
P24158

Gene Symbols:
PRTN3

Immunogen:
Monoclonal antibody WGM2 reacts with human proteinase 3 (PR3), a 30 kDa protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Inhibition Assays, Western Blot

Clone:
WGM2

Conjugate:
FITC

Gene:
PRTN3

Gene Alias:
ACPA; AGP7; azurophil granule protein 7; CANCA; C-ANCA; C-ANCA antigen; leukocyte proteinase 3; MBN; MBT; mPR3; Myeloblastin; neutrophil proteinase 4; NP4; NP-4; P29; PR3; PR-3; Proteinase 3; PRTN3; serine proteinase, neutrophil; wegener autoantigen; Wegener granulomatosis autoantigen

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5657

Content And Storage:
4° C, store in dark

Isotype:
IgG1

Img

Thermo Scientific

FERMA549096

--


Antigen:
PTX3

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.1% BSA and no preservative

Gene Accession No.:
P26022

Gene Symbols:
PTX3

Immunogen:
Human recombinant PTX3

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay, Inhibition Assays, Western Blot

Clone:
MNB1

Conjugate:
Unconjugated

Gene:
PTX3

Gene Alias:
AI607804; long pentraxin 3; pentaxin related; pentaxin-related protein PTX3; pentraxin 3; pentraxin 3, long; pentraxin related; pentraxin related gene; pentraxin-related protein PTX3; Ptx3; TNF alpha-induced protein 5; TNFAIP5; Tsg14; TSG-14; Tumor necrosis factor alpha-induced protein 5; tumor necrosis factor-inducible gene 14 protein; tumor necrosis factor-inducible protein TSG-14

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5806

Content And Storage:
4° C

Isotype:
IgG2b

Img

Thermo Scientific

FERMA549097

--


Antigen:
PTX3

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 1% BSA and 0.02% sodium azide

Gene Accession No.:
P26022

Gene Symbols:
PTX3

Immunogen:
Human recombinant PTX3

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Inhibition Assays, Western Blot

Clone:
MNB4

Conjugate:
FITC

Gene:
PTX3

Gene Alias:
AI607804; long pentraxin 3; pentaxin related; pentaxin-related protein PTX3; pentraxin 3; pentraxin 3, long; pentraxin related; pentraxin related gene; pentraxin-related protein PTX3; Ptx3; TNF alpha-induced protein 5; TNFAIP5; Tsg14; TSG-14; Tumor necrosis factor alpha-induced protein 5; tumor necrosis factor-inducible gene 14 protein; tumor necrosis factor-inducible protein TSG-14

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5806

Content And Storage:
4° C, store in dark

Isotype:
IgG2a

Img

Thermo Scientific

FERMA549098

--


Antigen:
PTX3

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.:
P26022

Gene Symbols:
PTX3

Immunogen:
Human recombinant PTX3

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Inhibition Assays, Western Blot

Clone:
MNB4

Conjugate:
Unconjugated

Gene:
PTX3

Gene Alias:
AI607804; long pentraxin 3; pentaxin related; pentaxin-related protein PTX3; pentraxin 3; pentraxin 3, long; pentraxin related; pentraxin related gene; pentraxin-related protein PTX3; Ptx3; TNF alpha-induced protein 5; TNFAIP5; Tsg14; TSG-14; Tumor necrosis factor alpha-induced protein 5; tumor necrosis factor-inducible gene 14 protein; tumor necrosis factor-inducible protein TSG-14

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5806

Content And Storage:
4° C

Isotype:
IgG2a