GR11L100UG

MilliporeSigma™ anti-IGF-IR Clone: αIR3,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 GR11L100UG-Each-of-1 In Stock ₹ 56,817.83

GR11L100UG - Each of 1

₹ 56,817.83

In Stock

Quantity

1

Base Price: ₹ 56,817.83

GST (18%): ₹ 10,227.209

Total Price: ₹ 67,045.039

Antigen

IGF-IR

Classification

Monoclonal

Conjugate

Unconjugated

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Purified

Applications

Immunofluorescence, Immunoprecipitation

Clone

αIR3

Formulation

In 0.05M sodium phosphate buffer, 0.2% gelatin.

Immunogen

partially purified, human placenta IGF-I receptor

Regulatory Status

RUO

Test Specificity

Recognizes the ∽130kDa α and the ∽90kDa β subunits of IGF-I receptor.

Content And Storage

2°C to 8°C

Isotype

IgG1

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Description

  • Specifically detects IGF-IR Clone: αIR3 in Human samples, and it is validated for Immunofluorescence, Immunoprecipitation The insulin-like growth factors (IGFs) or somatomedins are mitogenic peptides present in the plasma of human, rat, and other species
  • Two distinct but chemically related IGFs have been purified from human plasma: IGF-I (Somatomedin C) and IGF-II
  • They are single chain polypeptides with molecular weights of 7,640 and 7,471, respectively
  • Types I and II IGF receptors differ in their structure and in their peptide binding specificity
  • Type I IGF receptors are structurally homologous to insulin receptors and contain α-subunits (Mr=130,000) that bind peptide, and β-subunits (Mr=90,000), which have intrinsic tyrosine kinase activity
  • The protein-tyrosine kinase activity of the insulin receptor and, presumably the IGF-I receptor, is required for insulin to stimulate all of its biological responses in cells
  • Type II receptors are a single polypeptide (Mr=260,000), lack protein-tyrosine kinase activity, and have been shown to be identical to the mannose-6-phosphate receptor.

Compare Similar Items

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Img

MilliporeSigma™

GR11L100UG

--


Antigen:
IGF-IR

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
Immunofluorescence, Immunoprecipitation

Clone:
αIR3

Formulation:
In 0.05M sodium phosphate buffer, 0.2% gelatin.

Immunogen:
partially purified, human placenta IGF-I receptor

Regulatory Status:
RUO

Test Specificity:
Recognizes the ∽130kDa α and the ∽90kDa β subunits of IGF-I receptor.

Content And Storage:
2°C to 8°C

Isotype:
IgG1

Img

MilliporeSigma™

GR13100UG

--


Antigen:
EGFR

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunoprecipitation

Clone:
225

Formulation:
In 0.05M sodium phosphate buffer, 0.2% gelatin, ≤0.1% Sodium Azide.

Immunogen:
partially purified, human EGFR from A431 cells

Regulatory Status:
RUO

Test Specificity:
__

Content And Storage:
2°-8°C

Isotype:
IgG1

Img

MilliporeSigma™

GR13L100UG

--


Antigen:
EGFR

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
Immunoprecipitation

Clone:
225

Formulation:
In 0.05M sodium phosphate buffer, 0.2% gelatin.

Immunogen:
partially purified, human EGFR from A431 cells

Regulatory Status:
RUO

Test Specificity:
Recognizes the ∽170kDa epidermal growth factor receptor protein. For neutralization studies Cat. No. GR13L is recommended.

Content And Storage:
2°C to 8°C

Isotype:
IgG1

Img

MilliporeSigma™

GR15100UG

--


Antigen:
EGFR

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunoprecipitation

Clone:
EGFR.1

Formulation:
In 50mM sodium phosphate, 0.2% gelatin, pH 7.5, ≤0.1% Sodium Azide.

Immunogen:
partially purified, human EGFR from A431 cells

Regulatory Status:
RUO

Test Specificity:
__

Content And Storage:
2°-8°C

Isotype:
IgG