IM33100UG
MilliporeSigma™ anti-MMP-2 Clone: 42-5D11,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | IM33100UG-Each-of-1 | In Stock | ₹ 42,677.33 |
IM33100UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,677.33
GST (18%): ₹ 7,681.919
Total Price: ₹ 50,359.249
Antigen
MMP-2
Classification
Monoclonal
Conjugate
Unconjugated
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Bovine, Human, Mouse, Rat
Form
Purified
Applications
Immunoblot, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone
42-5D11
Formulation
In 100mM sodium phosphate buffer, 0.1% BSA, pH 7.0
Immunogen
a synthetic peptide (VTPRDKPMGPLLVATF) corresponding to amino acids 468-483 of human MMP-2
Regulatory Status
RUO
Test Specificity
Recognizes the ∽72kDa latent and the ∽66kDa active forms of the MMP-2.
Content And Storage
−20°C
Isotype
IgG1
Related Products
Description
- Specifically detects MMP-2 Clone: 42-5D11 in Bovine, Human, Mouse, Rat samples, and it is validated for Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immuno Blotting Matrix metalloproteinases (MMPs) are a family of enzymes that are responsible for the degradation of extracellular matrix components such as collagen, laminin, and proteoglycans
- In addition to sequence homology, all MMPs share the following characteristics: the catalytic mechanism is dependent upon a zinc ion at the active center, they cleave one or more extracellular matrix components, they are secreted as zymogens which are activated by removal of an approximately 10kDa segment from the N-terminus, and they are inhibited by tissue inhibitor of metalloproteinases (TIMP)
- These enzymes are involved in normal physiological processes such as embryogenesis and tissue remodeling and may play an important role in arthritis, periodontitis, and metastasis
- MMP-2 (Gelatinase A, 72kDa gelatinase/type IV collagenase, TBE-1) is secreted as a 72kDa zymogen which is proteolytically processed to the 66kDa active form
- MMP-2, along with its most closely related member of the MMP family, MMP-9, show substrate specificity toward type IV and V collagens, gelatin, and elastin
- Numerous studies have shown a correlation between collagenase expression and metastatic potential, and suggest that it may be a useful marker for the diagnosis or prognosis of cancer.
Compare Similar Items
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Antigen: MMP-2
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Bovine, Human, Mouse, Rat
Form: Purified
Applications: Immunoblot, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone: 42-5D11
Formulation: In 100mM sodium phosphate buffer, 0.1% BSA, pH 7.0
Immunogen: a synthetic peptide (VTPRDKPMGPLLVATF) corresponding to amino acids 468-483 of human MMP-2
Regulatory Status: RUO
Test Specificity: Recognizes the ∽72kDa latent and the ∽66kDa active forms of the MMP-2.
Content And Storage: −20°C
Isotype: IgG1
Antigen:
MMP-2
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Bovine, Human, Mouse, Rat
Form:
Purified
Applications:
Immunoblot, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone:
42-5D11
Formulation:
In 100mM sodium phosphate buffer, 0.1% BSA, pH 7.0
Immunogen:
a synthetic peptide (VTPRDKPMGPLLVATF) corresponding to amino acids 468-483 of human MMP-2
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽72kDa latent and the ∽66kDa active forms of the MMP-2.
Content And Storage:
−20°C
Isotype:
IgG1
Antigen: MMP-1
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Clone: 41-1E5
Formulation: In 100mM sodium phosphate buffer, 0.1% BSA, pH 7.0, ≤0.1% Sodium Azide.
Immunogen: a synthetic peptide (VQGQNVLHGYPKDIYSSFG) corresponding to amino acids 332-350 of human MMP-1
Regulatory Status: RUO
Test Specificity: __
Content And Storage: -20°C
Isotype: IgG
Antigen:
MMP-1
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Clone:
41-1E5
Formulation:
In 100mM sodium phosphate buffer, 0.1% BSA, pH 7.0, ≤0.1% Sodium Azide.
Immunogen:
a synthetic peptide (VQGQNVLHGYPKDIYSSFG) corresponding to amino acids 332-350 of human MMP-1
Regulatory Status:
RUO
Test Specificity:
__
Content And Storage:
-20°C
Isotype:
IgG
Antigen: MT1-MMP
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin)
Clone: 114-6G6
Formulation: In 100mM sodium phosphate buffer, 0.1% BSA, pH 7.0.
Immunogen: a synthetic peptide (REVPYAYIREGHEK) corresponding to amino acids 160-173 in the catalytic domain of human MT1-MMP
Regulatory Status: RUO
Test Specificity: Recognizes the ∽60-66kDa MTI-MMP protein in HT-1080 cells and ConA-treated MD-MB-231 cells.
Content And Storage: −20°C
Isotype: IgG1
Antigen:
MT1-MMP
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)
Clone:
114-6G6
Formulation:
In 100mM sodium phosphate buffer, 0.1% BSA, pH 7.0.
Immunogen:
a synthetic peptide (REVPYAYIREGHEK) corresponding to amino acids 160-173 in the catalytic domain of human MT1-MMP
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽60-66kDa MTI-MMP protein in HT-1080 cells and ConA-treated MD-MB-231 cells.
Content And Storage:
−20°C
Isotype:
IgG1
Antigen: MT1-MMP
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rabbit, Rat
Form: Purified
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Clone: 113-5B7
Formulation: In 100mM sodium phosphate buffer, 0.1% BSA, pH 7.0.
Immunogen: a synthetic peptide (CDGNFDTVAMLRGEM) corresponding to amino acids 319-333 in the hemopexin-like domain of human MT1-MMP
Regulatory Status: RUO
Test Specificity: Recognizes the ∽60kDa MTI-MMP protein in HT-1080 cells and in ConA-treated MD-MB-231 cells.
Content And Storage: −20°C
Isotype: IgG3
Antigen:
MT1-MMP
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rabbit, Rat
Form:
Purified
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Clone:
113-5B7
Formulation:
In 100mM sodium phosphate buffer, 0.1% BSA, pH 7.0.
Immunogen:
a synthetic peptide (CDGNFDTVAMLRGEM) corresponding to amino acids 319-333 in the hemopexin-like domain of human MT1-MMP
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽60kDa MTI-MMP protein in HT-1080 cells and in ConA-treated MD-MB-231 cells.
Content And Storage:
−20°C
Isotype:
IgG3