MA123304

CtIP Monoclonal Antibody (19E8), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA123304-Each-of-1 In Stock ₹ 47,956.38

MA123304 - Each of 1

₹ 47,956.38

In Stock

Quantity

1

Base Price: ₹ 47,956.38

GST (18%): ₹ 8,632.148

Total Price: ₹ 56,588.528

Antigen

CtIP

Classification

Monoclonal

Concentration

1.0 mg/mL

Formulation

PBS with 20% glycerol and no preservative; pH 7

Gene Accession No.

Q80YR6, Q99708

Gene Symbols

Rbbp8

Immunogen

Human CtIP

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

Applications

ChIP Assay, Immunocytochemistry, Immunoprecipitation, Proximity Ligation Assay, Western Blot

Clone

19E8

Conjugate

Unconjugated

Gene

Rbbp8

Gene Alias

9930104E21Rik; COM1; CtBP-interacting protein; CtIP; DNA endonuclease RBBP8; JWDS; RB binding protein 8, endonuclease; RBBP8; RBBP-8; retinoblastoma binding protein 8; retinoblastoma-binding protein 8; Retinoblastoma-interacting protein and myosin-like; RGD1308872; RIM; SAE2; SCKL2; Sporulation in the absence of SPO11 protein 2 homolog

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

225182, 5932

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • CtIP, a 125 kD protein, was originally found interacting with a transcription repressor, CtBP, through the PLDLS motif (CtBP-Interacting Protein) thus suggested a role in transcription
  • Studies have shown that CtIP also interacts with BRCA1 protein through the c-terminus BRCT domains also suggested that CtIP is a potential tumor suppressor
  • This CtIP-BRCA1 interaction can be disrupted by DNA damaging agents including UV or gamma-irradiation
  • Li et al (Nature 406, 210 - 215 (2000)) have shown that ATM phosphorylates CtIP at serine residues 664 and 745, and mutation of these sites abrogates the dissociation of BRCA1 from CtIP, resulting in persistent repression of BRCA1-dependent induction of GADD45 upon ionizing radiation.

Compare Similar Items

Show Difference

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Thermo Scientific

MA123304

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Antigen:
CtIP

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 20% glycerol and no preservative; pH 7

Gene Accession No.:
Q80YR6, Q99708

Gene Symbols:
Rbbp8

Immunogen:
Human CtIP

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
ChIP Assay, Immunocytochemistry, Immunoprecipitation, Proximity Ligation Assay, Western Blot

Clone:
19E8

Conjugate:
Unconjugated

Gene:
Rbbp8

Gene Alias:
9930104E21Rik; COM1; CtBP-interacting protein; CtIP; DNA endonuclease RBBP8; JWDS; RB binding protein 8, endonuclease; RBBP8; RBBP-8; retinoblastoma binding protein 8; retinoblastoma-binding protein 8; Retinoblastoma-interacting protein and myosin-like; RGD1308872; RIM; SAE2; SCKL2; Sporulation in the absence of SPO11 protein 2 homolog

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
225182, 5932

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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Thermo Scientific

MA123333

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Antigen:
FANCD2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q9BXW9

Gene Symbols:
FANCD2

Immunogen:
Human FANCD2 fusion protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
103

Conjugate:
Unconjugated

Gene:
FANCD2

Gene Alias:
2410150O07Rik; AU015151; BB137857; DKFZp762A223; FA4; FACD; FACD2; FAD; FAD2; FA-D2; FANCD; FANCD2; Fanconi anemia complementation group D2; Fanconi anemia D2 protein; Fanconi anemia group D2 protein; Fanconi anemia group D2 protein homolog; Fanconi anemia, complementation group D2; FLJ23826; Protein FACD2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
2177

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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MA123350

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Antigen:
RAD1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and no preservative; pH 7

Gene Accession No.:
O60671

Gene Symbols:
RAD1

Immunogen:
Amino terminal fragment of human Rad1 purified from E. coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
4126

Conjugate:
Unconjugated

Gene:
RAD1

Gene Alias:
cell cycle checkpoint protein Hrad1; cell cycle checkpoint protein RAD1; checkpoint control protein HRAD1; DNA repair exonuclease rad1 homolog; DNA repair exonuclease REC1; exonuclease homolog RAD1; hRAD1; mRAD1; RAD1; RAD1 checkpoint clamp component; RAD1 checkpoint DNA exonuclease; RAD1 homolog; RAD1 homolog (S. pombe); rad1-like DNA damage checkpoint protein; REC1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5810

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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MA124603

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Antigen:
CA125

Classification:
Monoclonal

Concentration:
8.4 mg/mL

Formulation:
PBS with 0.09% sodium azide, pH 7.5

Gene Accession No.:
Q8WXI7

Gene Symbols:
MUC16

Immunogen:
Purified, full length, native human protein from ovarian carcinoma.

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Clone:
X325

Conjugate:
Unconjugated

Gene:
MUC16

Gene Alias:
1110008I14Rik; Ca125; CA-125; CA125 ovarian cancer antigen; ca-ovarian; FLJ14303; Gm1480; MUC16; MUC-16; mucin 16; mucin 16, cell surface associated; mucin-16; Ovarian cancer-related tumor marker CA125; ovarian carcinoma antigen CA125; RGD1308422

Host Species:
Mouse

Purification Method:
Ion-exchange chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
94025

Content And Storage:
4° C, do not freeze

Form:
Liquid