Collagen I Monoclonal Antibody (COL-1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA126771-Each-of-1 | In Stock | ₹ 49,068.66 |
MA126771 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,068.66
GST (18%): ₹ 8,832.359
Total Price: ₹ 57,901.019
Antigen
Collagen I
Classification
Monoclonal
Concentration
7.4 mg/mL
Formulation
ascites with 15mM sodium azide
Gene Accession No.
P02452, P02453, P02454, P02456, P02465, P02466, P08123, P11087, Q01149, Q28668
Gene Symbols
COL1A1, COL1A2
Immunogen
Bovine skin collagen type I
Regulatory Status
RUO
Gene ID (Entrez)
100008997, 100347598, 100626716, 100738123, 1277, 1278, 12842, 12843, 282187, 282188, 29393, 84352
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Dot Blot, ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
COL-1
Conjugate
Unconjugated
Gene
COL1A2
Gene Alias
AA960264; AI325291; alpha 1 type I collagen; alpha 2 type I collagen; alpha 2 type I procollagen; alpha 2(I) collagen; alpha 2(I) procollagen; alpha 2(I)-collagen; alpha1 chain of type I collagen; alpha-1 collagen (I); alpha-1 type 1 collagen; alpha-1 type I collagen; alpha-1 type-1 collagen; alpha1(I) procollagen; alpha2 chain of type I collagen; alpha-2 type I collagen; alpha-2(1) collagen; alpha2(I) collagen; COL1; Col1a1; Col1a-1; COL1A1; matrix protein; Col1a2; Col1a-2; COLA; Cola1; Cola-1; Cola2; Cola-2; COLIA1; collagen; collagen 1 alpha 2 chain; collagen a2; collagen alpha 1 chain type I; collagen alpha 2(I) chain precursor; collagen alpha-1 chain; collagen alpha-1 chain precursor; collagen alpha-1(I) chain; collagen alpha-1(I) chain preproprotein; collagen alpha-2; collagen alpha-2 chain precursor; collagen alpha-2(I) chain; collagen COL1A2; collagen I alpha-2 polypeptide; collagen I, alpha-2 polypeptide; collagen of skin, tendon and bone, alpha-1 chain; collagen of skin, tendon and bone, alpha-2 chain; collagen type I alpha 1; collagen type I alpha 1 chain; collagen type I alpha 2 chain; collagen, type 1, alpha 1; collagen, type I, alpha 1; collagen, type I, alpha 2; EDSC; Mov13; Mov-13; OI1; OI2; OI3; OI4; oim; osteogenesis imperfecta; precollagen alpha-2; prepro-alpha-1 collagen type I; pro-alpha-1 collagen type 1; procollagen type I, alpha 1; procollagen, type 1, alpha 1; procollagen, type I, alpha 1; procollagen, type I, alpha 2; similar to pro alpha 1(I) collagen; Type I Collagen; type I collagen alpha 1 chain; type I collagen alpha1; type I collagen alpha-2 chain; type I collagen pre-pro-alpha1(I) chain; type I proalpha 1; type I procollagen; type I procollagen alpha 1 chain; type I-alpha 1 collagen
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Bovine, Deer, Human, Mouse, Porcine, Rabbit, Rat
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- The antibody is reactive with the native (helical) form of collagen type I in ELISA and dot blot
- The product is not reactive when tested on thermally denatured molecules
- In immunohistochemical staining of acetone-fixed and unfixed frozen sections, a strong staining of connective tissue fibers is seen
- Using the dot blot and ELISA techniques, the antibody shows no cross-reactivity with collagen types, II, III, IV, V, VI, VII, IX, X and XI
- The epitope recognized by the antibody is sensitive to routine formalin fixation and paraffin embedding.∣Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Collagen I is a Type I collagen with a triple helix structure comprised of two alpha-1 chains and one alpha-2 chain
- Collagen I is a member of group I collagen (fibril-forming collagen) found in most connective tissues, and is abundant in bone, cornea, dermis and tendon
- Mutations in the COL1A2 gene encoding the alpha-2 chain are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome
- Symptoms associated with mutations in the COL1A2 gene which codes for the alpha-2 chain, however, tend to be less severe than mutations in the COL1A1 gene, reflecting the different role of alpha-2 chains in matrix integrity
- Reciprocal translocations between chromosomes 17 and 22, where Collagen Type 1 genes and the gene for platelet derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor
- Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified.
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Antigen: Collagen I
Classification: Monoclonal
Concentration: 7.4 mg/mL
Formulation: ascites with 15mM sodium azide
Gene Accession No.: P02452, P02453, P02454, P02456, P02465, P02466, P08123, P11087, Q01149, Q28668
Gene Symbols: COL1A1, COL1A2
Immunogen: Bovine skin collagen type I
Regulatory Status: RUO
Gene ID (Entrez): 100008997, 100347598, 100626716, 100738123, 1277, 1278, 12842, 12843, 282187, 282188, 29393, 84352
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Dot Blot, ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: COL-1
Conjugate: Unconjugated
Gene: COL1A2
Gene Alias: AA960264; AI325291; alpha 1 type I collagen; alpha 2 type I collagen; alpha 2 type I procollagen; alpha 2(I) collagen; alpha 2(I) procollagen; alpha 2(I)-collagen; alpha1 chain of type I collagen; alpha-1 collagen (I); alpha-1 type 1 collagen; alpha-1 type I collagen; alpha-1 type-1 collagen; alpha1(I) procollagen; alpha2 chain of type I collagen; alpha-2 type I collagen; alpha-2(1) collagen; alpha2(I) collagen; COL1; Col1a1; Col1a-1; COL1A1; matrix protein; Col1a2; Col1a-2; COLA; Cola1; Cola-1; Cola2; Cola-2; COLIA1; collagen; collagen 1 alpha 2 chain; collagen a2; collagen alpha 1 chain type I; collagen alpha 2(I) chain precursor; collagen alpha-1 chain; collagen alpha-1 chain precursor; collagen alpha-1(I) chain; collagen alpha-1(I) chain preproprotein; collagen alpha-2; collagen alpha-2 chain precursor; collagen alpha-2(I) chain; collagen COL1A2; collagen I alpha-2 polypeptide; collagen I, alpha-2 polypeptide; collagen of skin, tendon and bone, alpha-1 chain; collagen of skin, tendon and bone, alpha-2 chain; collagen type I alpha 1; collagen type I alpha 1 chain; collagen type I alpha 2 chain; collagen, type 1, alpha 1; collagen, type I, alpha 1; collagen, type I, alpha 2; EDSC; Mov13; Mov-13; OI1; OI2; OI3; OI4; oim; osteogenesis imperfecta; precollagen alpha-2; prepro-alpha-1 collagen type I; pro-alpha-1 collagen type 1; procollagen type I, alpha 1; procollagen, type 1, alpha 1; procollagen, type I, alpha 1; procollagen, type I, alpha 2; similar to pro alpha 1(I) collagen; Type I Collagen; type I collagen alpha 1 chain; type I collagen alpha1; type I collagen alpha-2 chain; type I collagen pre-pro-alpha1(I) chain; type I proalpha 1; type I procollagen; type I procollagen alpha 1 chain; type I-alpha 1 collagen
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Bovine, Deer, Human, Mouse, Porcine, Rabbit, Rat
Product Type: Antibody
Isotype: IgG1
Antigen: Cathepsin D
Classification: Monoclonal
Concentration: 5.1 mg/mL
Formulation: Ascites with 15mM sodium azide
Gene Accession No.: P07339
Gene Symbols: Ctsd
Immunogen: Purified, full length, native protein from human liver.
Regulatory Status: RUO
Gene ID (Entrez): 1509
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
Clone: CTD-19
Conjugate: Unconjugated
Gene: Ctsd
Gene Alias: CatD; Cathepsin D; Cathepsin D heavy chain; Cathepsin D light chain; CathepsinD; CD; Ceroid lipofuscinosis neuronal 10; ceroid-lipofuscinosis, neuronal 10; CLN10; CPSD; CTSD; epididymis secretory sperm binding protein Li 130P; HEL-S-130P; lysosomal aspartyl peptidase; lysosomal aspartyl protease; MGC2311; OTTHUMP00000196039; OTTHUMP00000198692
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Antigen: Cathepsin L
Classification: Monoclonal
Concentration: 4.3 mg/mL
Formulation: Ascites with 15mM sodium azide
Gene Accession No.: P06797, P07154, P07711
Gene Symbols: CTSL
Immunogen: Purified, full length, native protein from human lung cancer line EPLC 32 M1.
Regulatory Status: RUO
Gene ID (Entrez): 13039, 1514, 25697
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunohistochemistry (Frozen), Western Blot
Clone: 33/2
Conjugate: Unconjugated
Gene: CTSL
Gene Alias: 1190035F06Rik; Cat L; cathepsin L; Cathepsin L1; Cathepsin L1 heavy chain; Cathepsin L1 light chain; CATHL; CatL; CP-2; Ctsl; CTSL1; cyclic protein 2; fs; furless; major excreted protein; MEP; nackt; nkt; p39 cysteine proteinase; Procathepsin L
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mink, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
