MA180122
TLR4 Monoclonal Antibody (HTA125), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA180122-Each-of-1 | In Stock | ₹ 73,239.36 |
MA180122 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 73,239.36
GST (18%): ₹ 13,183.085
Total Price: ₹ 86,422.445
Antigen
TLR4
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
O00206, Q68Y56
Gene Symbols
TLR4
Immunogen
Ba/F3 cell line expressing TLR4 (CD284).
Quantity
500 μg
Primary or Secondary
Primary
Target Species
Canine, Guinea Pig, Human, Porcine, Rhesus Monkey
Product Type
Antibody
Isotype
IgG2a
Applications
Flow Cytometry, Functional Assay, Immunoprecipitation
Clone
HTA125
Conjugate
Unconjugated
Gene
TLR4
Gene Alias
ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
100724803, 399541, 403417, 574360, 7099
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- This product is a low-endotoxin, preservative-free formulation
- Endotoxin level is <0.01 EU/ug
- For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
- Mouse anti Human CD284 antibody, clone HTA125 recognizes the human Toll like receptor 4 (TLR4) cell surface antigen
- TLR4 is member of the Toll like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity
- TLRs are highly conserved from Drosophila to humans and share structural and functional similarities
- This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes
- Mammalian cells respond to LPS by activating TLR4
- TLR4 belongs to the multi-protein complex of lipopolysaccharide (LPS) receptor, containing CD14, LY96 and TLR4, and is involved in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria
- TLR4 aids in the recognition of pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity
- The various TLRs exhibit different patterns of expression
- Mutations in the TLR4 gene have been associated with differences in LPS responsiveness
- Also, several transcript variants of the TLR4 gene have been found, but the protein coding potential of most of them is uncertain
- TLR4 is expressed by peripheral blood monocytes and a small population of B-cells and is also expressed in human placenta
- Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide
- Consequently, these mice also showed increased susceptibility to Gram-negative sepsis.
Compare Similar Items
Show Difference
Antigen: TLR4
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: O00206, Q68Y56
Gene Symbols: TLR4
Immunogen: Ba/F3 cell line expressing TLR4 (CD284).
Quantity: 500 μg
Primary or Secondary: Primary
Target Species: Canine, Guinea Pig, Human, Porcine, Rhesus Monkey
Product Type: Antibody
Isotype: IgG2a
Applications: Flow Cytometry, Functional Assay, Immunoprecipitation
Clone: HTA125
Conjugate: Unconjugated
Gene: TLR4
Gene Alias: ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 100724803, 399541, 403417, 574360, 7099
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
TLR4
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
O00206, Q68Y56
Gene Symbols:
TLR4
Immunogen:
Ba/F3 cell line expressing TLR4 (CD284).
Quantity:
500 μg
Primary or Secondary:
Primary
Target Species:
Canine, Guinea Pig, Human, Porcine, Rhesus Monkey
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Flow Cytometry, Functional Assay, Immunoprecipitation
Clone:
HTA125
Conjugate:
Unconjugated
Gene:
TLR4
Gene Alias:
ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
100724803, 399541, 403417, 574360, 7099
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: CD68
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: tissue culture supernatant with <0.1% sodium azide
Gene Accession No.: P34810
Gene Symbols: Cd68
Immunogen: Fusion protein of external domain of human CD68.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone: 514H12
Conjugate: Unconjugated
Gene: Cd68
Gene Alias: CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): 968
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
CD68
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
tissue culture supernatant with <0.1% sodium azide
Gene Accession No.:
P34810
Gene Symbols:
Cd68
Immunogen:
Fusion protein of external domain of human CD68.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone:
514H12
Conjugate:
Unconjugated
Gene:
Cd68
Gene Alias:
CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
968
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Calprotectin
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P05109, P06702, P28782, P28783, P50115, P50116, P50117
Gene Symbols: S100A8, S100A9
Immunogen: Human monocytes.
Quantity: 20 μg
Primary or Secondary: Primary
Target Species: Bovine, Canine, Deer, Equine, Feline, Goat, Guinea Pig, Human, Non-human Primate, Porcine, Rabbit, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone: MAC387
Conjugate: Unconjugated
Gene: S100A8
Gene Alias: 60B8Ag; AI323541; AW546964; B8Ag; BEE11; BEE22; CAGA; CAGB; calcium binding protein; S100 protein; calgranulin A; calgranulin B; calgranulin-A; Calgranulin-B; calprotectin; calprotectin L1H subunit; Calprotectin L1L subunit; CFAG; CGLA; CGLB; chemotactic cytokine CP-10; chemotactic S100 protein; CP-10; Cystic fibrosis antigen; EGK_01322; EGK_21438; GAGB; intracellular calcium-binding protein (MRP14); L1AG; Leukocyte L1 complex heavy chain; leukocyte L1 complex light chain; LIAG; LOC100735514; LOC532569 protein; MA387; MAC387; macrophage migration inhibitory factor-related protein-14; macrophage migration inhibitory factor-related protein-8; MIF; migration inhibitory factor-related protein 14; Migration inhibitory factor-related protein 8; Mrp14; MRP-14; MRP8; MRP-8; myeloid-related protein 14; Neutrophil cytosolic 23 kDa protein; neutrophil cytosolic 7 kDa protein; NIF; p14; p23; P7; p8; Pro-inflammatory S100 cytokine; protein S100-A8; Protein S100-A9; S100 calcium binding protein A8; S100 calcium binding protein A8 (calgranulin A); S100 calcium binding protein A9; S100 calcium binding protein A9 (calgranulin B); S100 calcium binding protein A9; protein S100-A9; S100 calcium-binding protein A8; S100 calcium-binding protein A8 (calgranulin A); S100 calcium-binding protein A9; S100 calcium-binding protein A9 (calgranulin B); S100a8; S100A8/S100A9; S100a9; similar to Calgranulin A (Migration inhibitory factor-related protein 8) (MRP-8) (Cystic fibrosis antigen) (CFAG) (P8) (Leukocyte L1 complex light chain) (S100 calcium-binding protein A8) (Calprotectin L1L subunit) (Urinary stone protein band A)...; urinary stone protein band A
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 100008704, 100008985, 100061730, 100061766, 100127488, 100127489, 100735238, 100735514, 101084164, 101084419, 102168876, 102182273, 116547, 490461, 490463, 532569, 616818, 6279, 6280, 94195
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Calprotectin
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P05109, P06702, P28782, P28783, P50115, P50116, P50117
Gene Symbols:
S100A8, S100A9
Immunogen:
Human monocytes.
Quantity:
20 μg
Primary or Secondary:
Primary
Target Species:
Bovine, Canine, Deer, Equine, Feline, Goat, Guinea Pig, Human, Non-human Primate, Porcine, Rabbit, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone:
MAC387
Conjugate:
Unconjugated
Gene:
S100A8
Gene Alias:
60B8Ag; AI323541; AW546964; B8Ag; BEE11; BEE22; CAGA; CAGB; calcium binding protein; S100 protein; calgranulin A; calgranulin B; calgranulin-A; Calgranulin-B; calprotectin; calprotectin L1H subunit; Calprotectin L1L subunit; CFAG; CGLA; CGLB; chemotactic cytokine CP-10; chemotactic S100 protein; CP-10; Cystic fibrosis antigen; EGK_01322; EGK_21438; GAGB; intracellular calcium-binding protein (MRP14); L1AG; Leukocyte L1 complex heavy chain; leukocyte L1 complex light chain; LIAG; LOC100735514; LOC532569 protein; MA387; MAC387; macrophage migration inhibitory factor-related protein-14; macrophage migration inhibitory factor-related protein-8; MIF; migration inhibitory factor-related protein 14; Migration inhibitory factor-related protein 8; Mrp14; MRP-14; MRP8; MRP-8; myeloid-related protein 14; Neutrophil cytosolic 23 kDa protein; neutrophil cytosolic 7 kDa protein; NIF; p14; p23; P7; p8; Pro-inflammatory S100 cytokine; protein S100-A8; Protein S100-A9; S100 calcium binding protein A8; S100 calcium binding protein A8 (calgranulin A); S100 calcium binding protein A9; S100 calcium binding protein A9 (calgranulin B); S100 calcium binding protein A9; protein S100-A9; S100 calcium-binding protein A8; S100 calcium-binding protein A8 (calgranulin A); S100 calcium-binding protein A9; S100 calcium-binding protein A9 (calgranulin B); S100a8; S100A8/S100A9; S100a9; similar to Calgranulin A (Migration inhibitory factor-related protein 8) (MRP-8) (Cystic fibrosis antigen) (CFAG) (P8) (Leukocyte L1 complex light chain) (S100 calcium-binding protein A8) (Calprotectin L1L subunit) (Urinary stone protein band A)...; urinary stone protein band A
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
100008704, 100008985, 100061730, 100061766, 100127488, 100127489, 100735238, 100735514, 101084164, 101084419, 102168876, 102182273, 116547, 490461, 490463, 532569, 616818, 6279, 6280, 94195
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: CD169
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: 0
Gene Symbols: SIGLEC1
Immunogen: Rat Spleen cell homogenate.
Quantity: 250 μg
Primary or Secondary: Primary
Target Species: Rat
Product Type: Antibody
Isotype: IgG2a
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation
Clone: ED3
Conjugate: Unconjugated
Gene: SIGLEC1
Gene Alias: Cd169; dJ1009E24.1; macrophage receptor; p210; pSn; SA; SER; sheep erythrocyte receptor; sialic acid binding Ig like lectin 1; sialic acid binding Ig-like lectin 1, sialoadhesin; Sialic acid-binding Ig-like lectin 1; sialic acid-binding immunoglobulin-like lectin 1; sialoadhesin; SIGLEC1; Siglec-1; SN
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 311426
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
CD169
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
0
Gene Symbols:
SIGLEC1
Immunogen:
Rat Spleen cell homogenate.
Quantity:
250 μg
Primary or Secondary:
Primary
Target Species:
Rat
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation
Clone:
ED3
Conjugate:
Unconjugated
Gene:
SIGLEC1
Gene Alias:
Cd169; dJ1009E24.1; macrophage receptor; p210; pSn; SA; SER; sheep erythrocyte receptor; sialic acid binding Ig like lectin 1; sialic acid binding Ig-like lectin 1, sialoadhesin; Sialic acid-binding Ig-like lectin 1; sialic acid-binding immunoglobulin-like lectin 1; sialoadhesin; SIGLEC1; Siglec-1; SN
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
311426
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid