MA180446

Calprotectin Monoclonal Antibody (MAC387), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA180446-Each-of-1 In Stock ₹ 71,784.84

MA180446 - Each of 1

₹ 71,784.84

In Stock

Quantity

1

Base Price: ₹ 71,784.84

GST (18%): ₹ 12,921.271

Total Price: ₹ 84,706.111

Antigen

Calprotectin

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P05109, P06702, P28782, P28783, P50115, P50116, P50117

Gene Symbols

S100A8, S100A9

Immunogen

Human monocytes.

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Bovine, Canine, Deer, Equine, Feline, Goat, Guinea Pig, Human, Non-human Primate, Porcine, Rabbit, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone

MAC387

Conjugate

Unconjugated

Gene

S100A8

Gene Alias

60B8Ag; AI323541; AW546964; B8Ag; BEE11; BEE22; CAGA; CAGB; calcium binding protein; S100 protein; calgranulin A; calgranulin B; calgranulin-A; Calgranulin-B; calprotectin; calprotectin L1H subunit; Calprotectin L1L subunit; CFAG; CGLA; CGLB; chemotactic cytokine CP-10; chemotactic S100 protein; CP-10; Cystic fibrosis antigen; EGK_01322; EGK_21438; GAGB; intracellular calcium-binding protein (MRP14); L1AG; Leukocyte L1 complex heavy chain; leukocyte L1 complex light chain; LIAG; LOC100735514; LOC532569 protein; MA387; MAC387; macrophage migration inhibitory factor-related protein-14; macrophage migration inhibitory factor-related protein-8; MIF; migration inhibitory factor-related protein 14; Migration inhibitory factor-related protein 8; Mrp14; MRP-14; MRP8; MRP-8; myeloid-related protein 14; Neutrophil cytosolic 23 kDa protein; neutrophil cytosolic 7 kDa protein; NIF; p14; p23; P7; p8; Pro-inflammatory S100 cytokine; protein S100-A8; Protein S100-A9; S100 calcium binding protein A8; S100 calcium binding protein A8 (calgranulin A); S100 calcium binding protein A9; S100 calcium binding protein A9 (calgranulin B); S100 calcium binding protein A9; protein S100-A9; S100 calcium-binding protein A8; S100 calcium-binding protein A8 (calgranulin A); S100 calcium-binding protein A9; S100 calcium-binding protein A9 (calgranulin B); S100a8; S100A8/S100A9; S100a9; similar to Calgranulin A (Migration inhibitory factor-related protein 8) (MRP-8) (Cystic fibrosis antigen) (CFAG) (P8) (Leukocyte L1 complex light chain) (S100 calcium-binding protein A8) (Calprotectin L1L subunit) (Urinary stone protein band A)...; urinary stone protein band A

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

100008704, 100008985, 100061730, 100061766, 100127488, 100127489, 100735238, 100735514, 101084164, 101084419, 102168876, 102182273, 116547, 490461, 490463, 532569, 616818, 6279, 6280, 94195

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This clone recognizes the L1 or Calprotectin molecule, an intracytoplasmic antigen comprised of a 12 kDa alpha chain and a 14 kDa beta chain
  • Although originally described as binding to epitopes common to both the alpha and beta chains (Flavell et al
  • 1987) subsequent studies indicate that the antibody detects an epitope exclusively expressed on the beta chain (Goebeler et al
  • 1994) demonstrated by immunofluorescent and western blotting on both naturally expressing and transfected targets
  • In addition Mouse anti Human macrophages, clone MAC387 detects the beta chain in complex with the alpha
  • The antigen recognized by Mouse anti Human macrophages, clone MAC387 is expressed by granulocytes, monocytes and by tissue macrophages
  • Variable results have been reported for staining brain macrophages and microglia
  • The epitope recognized appears to be well conserved and the antibody is routinely used for the detection of myeloid cellds in a wide range of species
  • This product requires protein digestion pre-treatment of paraffin sections using trypsin or pronase prior to IHC staining
  • A suggested positive control is human spleen
  • For flow cytometry, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
  • The S100A8/A9 heterocomplex, also called MRP-8/MRP-14 complex or calprotectin, comprises 60% of the cytoplasmic protein fraction of circulating polymorphonuclear granulocytes and is also found in monocytes, macrophages and ileal tissue eosinophils
  • Peripheral blood monocytes carry the antigen extra- and intracellularly, neutrophils only intracellularly
  • The S100A8/A9 complex has antibacterial, antifungal, immunomodulating and antiproliferative effects
  • Besides this it is a potent chemotactic factor for neutrophils
  • Plasma concentrations are elevated in diseases associated with increased neutrophil activity, like inflammatory bowel disease
  • Granulocytes terminate their existence after transmigration through the intestinal wall
  • Therefore calprotectin is also detectable in feces
  • Elevated levels of calprotectin have been observed in body fluids such as plasma, saliva, gingival crevicular fluid, stools, and synovial fluid during infection and inflammatory conditions.

Compare Similar Items

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Thermo Scientific

MA180446

--


Antigen:
Calprotectin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P05109, P06702, P28782, P28783, P50115, P50116, P50117

Gene Symbols:
S100A8, S100A9

Immunogen:
Human monocytes.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Deer, Equine, Feline, Goat, Guinea Pig, Human, Non-human Primate, Porcine, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
MAC387

Conjugate:
Unconjugated

Gene:
S100A8

Gene Alias:
60B8Ag; AI323541; AW546964; B8Ag; BEE11; BEE22; CAGA; CAGB; calcium binding protein; S100 protein; calgranulin A; calgranulin B; calgranulin-A; Calgranulin-B; calprotectin; calprotectin L1H subunit; Calprotectin L1L subunit; CFAG; CGLA; CGLB; chemotactic cytokine CP-10; chemotactic S100 protein; CP-10; Cystic fibrosis antigen; EGK_01322; EGK_21438; GAGB; intracellular calcium-binding protein (MRP14); L1AG; Leukocyte L1 complex heavy chain; leukocyte L1 complex light chain; LIAG; LOC100735514; LOC532569 protein; MA387; MAC387; macrophage migration inhibitory factor-related protein-14; macrophage migration inhibitory factor-related protein-8; MIF; migration inhibitory factor-related protein 14; Migration inhibitory factor-related protein 8; Mrp14; MRP-14; MRP8; MRP-8; myeloid-related protein 14; Neutrophil cytosolic 23 kDa protein; neutrophil cytosolic 7 kDa protein; NIF; p14; p23; P7; p8; Pro-inflammatory S100 cytokine; protein S100-A8; Protein S100-A9; S100 calcium binding protein A8; S100 calcium binding protein A8 (calgranulin A); S100 calcium binding protein A9; S100 calcium binding protein A9 (calgranulin B); S100 calcium binding protein A9; protein S100-A9; S100 calcium-binding protein A8; S100 calcium-binding protein A8 (calgranulin A); S100 calcium-binding protein A9; S100 calcium-binding protein A9 (calgranulin B); S100a8; S100A8/S100A9; S100a9; similar to Calgranulin A (Migration inhibitory factor-related protein 8) (MRP-8) (Cystic fibrosis antigen) (CFAG) (P8) (Leukocyte L1 complex light chain) (S100 calcium-binding protein A8) (Calprotectin L1L subunit) (Urinary stone protein band A)...; urinary stone protein band A

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
100008704, 100008985, 100061730, 100061766, 100127488, 100127489, 100735238, 100735514, 101084164, 101084419, 102168876, 102182273, 116547, 490461, 490463, 532569, 616818, 6279, 6280, 94195

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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MA180453

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Antigen:
HLA-ABC

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P01889, P04439, P10321

Gene Symbols:
HLA-A, HLA-B, HLA-C

Immunogen:
Purified human tonsil lymphocyte membranes.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Non-human Primate, Shrew

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry

Clone:
W6/32

Conjugate:
Biotin

Gene:
HLA-C

Gene Alias:
A29 protein; alpha chain of MHC class II; antigen presenting molecule; AS; Aw-33; Aw-74; B-4901; B-5001; Bw-47; Bw-50; class I MHC, HLA-B antigen; D6S204; epididymis secretory protein Li 83; H-2K; H2-K; H-2K(d); HEL-S-83; histocompatibility antigen; HLA A; HLA -B; HLA B-40011; HLA B44; HLA C; HLA class I antigen; HLA class I antigen HLA-B; HLA class I histocompatibility antigen C alpha chain; HLA class I histocompatibility antigen Cw-1 alpha chain; HLA class I histocompatibility antigen, A alpha chain; HLA class I histocompatibility antigen, A-1 alpha chain; HLA class I histocompatibility antigen, A-11 alpha chain-like; HLA class I histocompatibility antigen, A-30 alpha chain; HLA class I histocompatibility antigen, A-33 alpha chain; HLA class I histocompatibility antigen, A-74 alpha chain; HLA class I histocompatibility antigen, B alpha chain; HLA class I histocompatibility antigen, B-47 alpha chain; HLA class I histocompatibility antigen, B-50 alpha chain; HLA class I histocompatibility antigen, B-82 alpha chain; HLA class I histocompatibility antigen, C alpha chain; HLA class I histocompatibility antigen, Cw-1 alpha chain; HLA class I histocompatibility antigen, Cw-15 alpha chain; HLA class I histocompatibility antigen, Cw-18 alpha chain; HLA locus; HLA molecule; HLAA; HLA-A; HLA-A locus alpha 2 domain; HLA-A null; HLA-A11; HLA-A33; HLA-Aw33.1; HLAB; HLA-B; HLA-B 1502; HLA-B alpha chain; HLA-B alpha chain (B*2706); HLA-B alpha chain (B*5002); HLA-B alpha-chain; HLA-B*45ZJ; HLA-B15; HLA-B35; HLA-B35 antigen; HLA-B-3506; HLA-B39; HLA-B-3905; HLA-B49; HLA-B50; HLA-B55; HLA-B-5502; HLA-B-5602; HLA-B59; HLA-B61; HLA-Bw50 antigen; HLAC; HLA-C; HLA-C alpha chain; HLA-C alpha chain (HLA-Cw*15v); HLA-C alpha chain for Cw*18GB; HLA-C alpha-chain; HLA-C antigen; HLA-Cw; HLA-Cw*04GB; HLA-Cw*1702; HLA-Cw*18GB; HLA-Cw-1503; HLA-DQB1; HLA-DRB1; HLA-JY3; HLC-C; Human leukocyte antigen A; Human leukocyte antigen C; human leukocyte antigen-C alpha chain; hypothetical protein; lecocyte antigen B; leucocyte antigen A; Leukocyte Antigen; leukocyte antigen C; leukocyte antigen class I-A; leukocyte antigen class I-B; Leukoocyte Antigen; LOC100515902; LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, A-11 alpha chain-like; lymphocyte antigen; major histocompatability complex B antigen; major histocompatibility antigen HLA-C; major histocompatibility complex, class I, A; major histocompatibility complex, class I, B; major histocompatibility complex, class I, C; MCH class I antigen; MGC184092; MGC7052; MHC; MHC 1; MHC antigen; MHC clas I antigen; MHC Class 1; MHC class 1 antigen; MHC class I; MHC class I alpha chain; MHC class I anitgen; MHC class I anti; MHC Class I antigen; MHC class I antigen A*30; MHC class I antigen A*33; MHC class I antigen A*74; MHC class I antigen B*47; MHC class I antigen B*50; MHC class I antigen B*82; MHC class I antigen Cw*15; MHC class I antigen Cw*18; MHC class I antigen GN00104; MHC class I antigen heavy chain; MHC class I antigen heavy chain HLA-C; MHC class I antigen HLA-A heavy chain; MHC class I antigen HLA-A33; MHC class I antigen HLA-B alpha chain; MHC class I antigen HLA-B heavy chain; MHC class I antigen null protein; MHC class I antigen SHCHA; MHC class I antigene; MHC class I histocompatibility antigen; MHC class I human leukocyte antigen; MHC class I molecule; MHC class I protein; MHC class II antigen; MHC class l antigen; MHC classI antigen; MHC HLA-ABC; MHC HLA-B cell surface glycoprotein; MHC HLA-B transmembrane glycoprotein; MHC HLA-B27d; MHC HLA-B27-HS; MHC HLA-B39N; MHC I HLA; MHC1; PSORS1; SPDA1; surface antigen; truncated class I antigen; truncated MHC class I antigen

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3105, 3106, 3107

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

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MA180456

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Antigen:
IL-6 Receptor

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with <0.1% sodium azide

Gene Accession No.:
P08887

Gene Symbols:
IL6R

Immunogen:
CHO cells transfected with cDNA of the IL-6 receptor.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation

Clone:
B-R6

Conjugate:
Unconjugated

Gene:
IL6R

Gene Alias:
CD126; CD126 antigen; gp80; IL-6 Receptor; il-6 receptor alpha; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; IL6Q; IL6R; IL-6R; IL-6R 1; IL-6R subunit alpha; IL6R1; IL-6R-1; Il6ra; IL-6RA; IL-6R-alpha; IL6RQ; ILN; Interleukin; interleukin 6 receptor; interleukin 6 receptor, alpha; interleukin-6 receptor subunit alpha; Membrane glycoprotein 80; MGC104991

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3570

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

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MA180461

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Antigen:
CD4

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 1% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P46630

Gene Symbols:
CD4

Immunogen:
Rabbit thymocytes.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Rabbit

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry

Clone:
KEN-4

Conjugate:
FITC

Gene:
CD4

Gene Alias:
Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
100009152

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Form:
Liquid