MA180485
CD11b Monoclonal Antibody (M1/70.15), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA180485-Each-of-1 | In Stock | ₹ 59,892.00 |
MA180485 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 59,892.00
GST (18%): ₹ 10,780.56
Total Price: ₹ 70,672.56
Antigen
CD11b
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P05555, P11215
Gene Symbols
ITGAM, LOC100351865
Immunogen
T cell enriched splenocytes from B10 mice.
Quantity
250 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rabbit
Product Type
Antibody
Isotype
IgG2b
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
Clone
M1/70.15
Conjugate
Unconjugated
Gene
ITGAM
Gene Alias
antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; LOC100351865; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product
Host Species
Rat
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
100351865, 16409, 3684
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This clone has been reported to block iC3b binding to its receptor
- PLP fixation is recommended for optimal tissue staining results
- Rat anti Mouse CD11b antibody, clone M1/70.15 recognizes the murine CD11b cell surface antigen also known as the alpha M integrin chain or MAC-1, a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages
- Rat anti Mouse CD11b antibody, clone M1/70.15 recognizes the murine CD11b cell surface antigen also known as the alpha M integrin chain or MAC-1, a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages
- CD11b (integrin alpha-M, ITGAM, integrin alpha-X, ITGAX) is a 165 kDa adhesion molecule that associates non-covalently with integrin beta-2 (CD18)
- The CD11b/CD18 heterodimeric complex is also known as integrin alpha-M beta-2, Mac-1, and CR3 (complement receptor 3)
- CD11b is expressed on the surface of monocytes/macrophages, granulocytes, activated lymphocytes, a subset of NK cells, a subset of dendritic cells, and microglia in the brain
- CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X -these adhesions are critical for cell-cell and cell-matrix interactions
- CD11b is expressed on 8% of spleen cells, 44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue
- The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages
- Further, peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages
- Diseases associated with CD11b dysfunction include systemic lupus erythematosus 6 and ITGAM-related susceptibility to systemic lupus erythematosus.
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Antigen: CD11b
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P05555, P11215
Gene Symbols: ITGAM, LOC100351865
Immunogen: T cell enriched splenocytes from B10 mice.
Quantity: 250 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rabbit
Product Type: Antibody
Isotype: IgG2b
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
Clone: M1/70.15
Conjugate: Unconjugated
Gene: ITGAM
Gene Alias: antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; LOC100351865; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product
Host Species: Rat
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 100351865, 16409, 3684
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
CD11b
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P05555, P11215
Gene Symbols:
ITGAM, LOC100351865
Immunogen:
T cell enriched splenocytes from B10 mice.
Quantity:
250 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rabbit
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
Clone:
M1/70.15
Conjugate:
Unconjugated
Gene:
ITGAM
Gene Alias:
antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; LOC100351865; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product
Host Species:
Rat
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
100351865, 16409, 3684
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: CD11b
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: PBS with 1% BSA, 5% sucrose and 0.09% sodium azide; pH 7.4
Gene Accession No.: P05555, P11215
Gene Symbols: ITGAM, LOC100351865
Immunogen: T cells enriched splenocytes from B10 mice.
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human, Mouse, Rabbit
Product Type: Antibody
Isotype: IgG2b
Applications: Flow Cytometry
Clone: M1/70.15
Conjugate: PE
Gene: ITGAM
Gene Alias: antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; LOC100351865; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product
Host Species: Rat
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 100351865, 16409, 3684
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Lyophilized
Antigen:
CD11b
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
PBS with 1% BSA, 5% sucrose and 0.09% sodium azide; pH 7.4
Gene Accession No.:
P05555, P11215
Gene Symbols:
ITGAM, LOC100351865
Immunogen:
T cells enriched splenocytes from B10 mice.
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rabbit
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Flow Cytometry
Clone:
M1/70.15
Conjugate:
PE
Gene:
ITGAM
Gene Alias:
antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; LOC100351865; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product
Host Species:
Rat
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
100351865, 16409, 3684
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Lyophilized
Antigen: ITGA4
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.1% sodium azide
Gene Accession No.: P13612, Q00651
Gene Symbols: ITGA4
Immunogen: JM leukemia line.
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human, Multi-species, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation
Clone: HP2/1
Conjugate: Unconjugated
Gene: ITGA4
Gene Alias: 269C wild type; alpha 4 subunit of VLA-4 receptor; antigen CD49D, alpha-4 subunit of VLA-4 receptor; CD49 antigen-like family member D; CD49d; IA4; integrin alpha 4; integrin alpha-4; integrin alpha4B; Integrin alpha-IV; integrin subunit alpha 4; integrin, alpha 4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor); Itga4; Itga4B; ITGA-IV; LPAM subunit alpha; lymphocyte Peyer patch adhesion molecules subunit alpha; very late activation protein 4 receptor, alpha 4 subunit; VLA-4 receptor, alpha 4 subunit; VLA-4 subunit alpha
Host Species: Mouse
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 16401, 311144, 3676
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
ITGA4
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% sodium azide
Gene Accession No.:
P13612, Q00651
Gene Symbols:
ITGA4
Immunogen:
JM leukemia line.
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human, Multi-species, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation
Clone:
HP2/1
Conjugate:
Unconjugated
Gene:
ITGA4
Gene Alias:
269C wild type; alpha 4 subunit of VLA-4 receptor; antigen CD49D, alpha-4 subunit of VLA-4 receptor; CD49 antigen-like family member D; CD49d; IA4; integrin alpha 4; integrin alpha-4; integrin alpha4B; Integrin alpha-IV; integrin subunit alpha 4; integrin, alpha 4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor); Itga4; Itga4B; ITGA-IV; LPAM subunit alpha; lymphocyte Peyer patch adhesion molecules subunit alpha; very late activation protein 4 receptor, alpha 4 subunit; VLA-4 receptor, alpha 4 subunit; VLA-4 subunit alpha
Host Species:
Mouse
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
16401, 311144, 3676
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: CD11b
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: 0
Gene Symbols: ITGAM
Immunogen: Rat spleen cell homogenate.
Quantity: 250 μg
Primary or Secondary: Primary
Target Species: Rat
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen)
Clone: ED7
Conjugate: Unconjugated
Gene: ITGAM
Gene Alias: antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; LOC100351865; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 25021
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
CD11b
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
0
Gene Symbols:
ITGAM
Immunogen:
Rat spleen cell homogenate.
Quantity:
250 μg
Primary or Secondary:
Primary
Target Species:
Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen)
Clone:
ED7
Conjugate:
Unconjugated
Gene:
ITGAM
Gene Alias:
antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; LOC100351865; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
25021
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid