MA523519

Cas9 Monoclonal Antibody (7A9), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA523519-Each-of-1 In Stock ₹ 57,581.88

MA523519 - Each of 1

₹ 57,581.88

In Stock

Quantity

1

Base Price: ₹ 57,581.88

GST (18%): ₹ 10,364.738

Total Price: ₹ 67,946.618

Antigen

Cas9

Classification

Monoclonal

Concentration

2 mg/mL

Formulation

PBS with 0.05% sodium azide; pH 7.4

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Target Species

Bacteria

Product Type

Antibody

Isotype

IgG1 κ

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Clone

7A9

Conjugate

Unconjugated

Gene Alias

cas9; CASP 9; Caspase9; Caspase-9 precursor; CASPASE-9c; CRISPR9; CRISPR-Cas9; CTD; OTTHUMP00000002324; RNCASP9; RP11-265F14.3; s aureus

Immunogen

Cas9 nuclease (CRISPR-associated protein 9).

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

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Description

  • MA5-23519 is derived from Streptococcus pyogenes
  • Cas9 is an RNA-guided DNA endonuclease enzyme associated with the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) adaptive immunity system in bacteria and genetic engineering
  • The system is unique and flexible due to its dependence on RNA as the element that targets the nuclease to a desired DNA sequence
  • It can be used to induce indel mutations, specific sequence replacements/insertions, and large deletions or genomic rearrangements at any desired location in the genome
  • In addition, Cas9 can also be used to mediate upregulation of specific endogenous genes or to alter histone modifications or DNA methylation
  • Cas9 may be derived from Streptococcus pyogenes (SpCas9) or Staphylococcus aureus (SaCas9)
  • SaCas9 has a number of properties that make it advantageous for genome editing, including its small size, high efficiency, nickase activity, and apparent specificity
  • SaCas9 principally recognizes an NNGRRT protospacer adjacent motif (PAM) and cleaves target DNA at rates comparable to SpCas9 with an ideal spacer lengths of 24 to 20 nucleotides
  • In comparison to SpCas9, SaCas9 is smaller (1368 AA versus 1053 AA) and generates indels at a comparable rate when directed against target DNA with the mutually permissive NGGRRT PAM
  • This makes it the preferred enzyme for all-in-one delivery of Cas9 and multiple gRNA expression cassettes with Adeno-associated vectors.

Compare Similar Items

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Thermo Scientific

MA523519

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Antigen:
Cas9

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.05% sodium azide; pH 7.4

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Target Species:
Bacteria

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
7A9

Conjugate:
Unconjugated

Gene Alias:
cas9; CASP 9; Caspase9; Caspase-9 precursor; CASPASE-9c; CRISPR9; CRISPR-Cas9; CTD; OTTHUMP00000002324; RNCASP9; RP11-265F14.3; s aureus

Immunogen:
Cas9 nuclease (CRISPR-associated protein 9).

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Img

Thermo Scientific

MA523522

--


Antigen:
BICD2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
3I3

Conjugate:
Unconjugated

Gene Alias:
bA526D8.1; bicaudal D homolog 2; bicaudal D homolog 2 (Drosophila); bicaudal D protein; Bic-D 2; BICD cargo adaptor 2; BICD2; coiled-coil protein BICD2; cytoskeleton-like bicaudal D protein homolog 2; homolog of Drosophila bicaudal D; KIAA0699; Protein bicaudal D homolog 2; RP11-476B13.3; SMALED2

Immunogen:
Recombinant protein encompassing a sequence within the N-terminus region of human BICD2.

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

MA523523

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Antigen:
RNaseH2B

Classification:
Monoclonal

Concentration:
1.94 mg/mL

Formulation:
PBS with no preservative

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
3I4

Conjugate:
Unconjugated

Gene Alias:
1110019N06Rik; 2610207P08Rik; AGS2; Aicardi-Goutieres syndrome 2 protein; Deleted in lymphocytic leukemia 8; deleted in lymphocytic leukemia 8 homolog; DLEU8; ribonuclease H2; ribonuclease H2 subunit B; ribonuclease H2, subunit B; ribonuclease HI subunit B; RNase H2 subunit B; Rnaseh2b

Immunogen:
Recombinant protein encompassing a sequence within the center region of human RNaseH2B.

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

MA523524

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Antigen:
ME1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
3I6

Conjugate:
Unconjugated

Gene Alias:
cytosolic malic enzyme 1; D9Ertd267e; HUMNDME; malate dehydrogenase; malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+); malate dehydrogenase decarboxylase (NADP+); malic enzyme; malic enzyme 1; malic enzyme 1, NADP(+)-dependent, cytoplasmic (cytosolic, soluble); malic enzyme 1, NADP(+)-dependent, cytosolic; malic enzyme 1, soluble; Malic enzyme, cytoplasmic; malic enzyme, supernatant; Mdh-1; ME1; MES; Mod1; Mod-1; NADP-dependent malic enzyme; NADP-dependent malic enzyme-like protein; NADP-ME; pyruvic-malic carboxylase

Immunogen:
Recombinant protein encompassing a sequence within the center region of human ME1.

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid