MABE1126MI

DNA G-quadruplex (G4) Mouse anti-All, Clone: 1H6, MilliporeSigma™

Manufacturer: MilliporeSigma

Select a Size

Pack Size SKU Availability Price
Each of 1 MABE1126MI-Each-of-1 In Stock ₹ 45,381.02

MABE1126MI - Each of 1

₹ 45,381.02

In Stock

Quantity

1

Base Price: ₹ 45,381.02

GST (18%): ₹ 8,168.584

Total Price: ₹ 53,549.604

Antigen

DNA G-quadruplex (G4)

Classification

Monoclonal

Concentration

Please refer to lot specific datasheet.

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

All species

Form

Purified

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), ELISA, Flow Cytometry

Clone

1H6

Conjugate

Unconjugated

Immunogen

KLH-conjugated G-quadruplex DNA derived from oligonucleotides with telomeric repeats.

Quantity

100 μg

Research Discipline

Epigenetics and Nuclear Function

Test Specificity

Clone 1H6 binds both tetramolecular and unimolecular (intramolecular) DNA G-quadruplex (G4) structures without sequence specificity, while exhibiting significantly lower affinity toward tetramolecular RNA structure or a triplex DNA structure, and little to no affinity toward either non-G4 ssDNA or ddDNA. However, clone 1H6 does not seem to bind the [AGGG(TTAGGG)3] unimolecular G4 structure, indicating a broad selectivity toward many, but not all, DNA G4 structures (Henderson, A., et al. (2014). Nucleic Acids Res. 42(2):860-869).

Content And Storage

Stable for 1 year at 2-8°C from date of receipt.

Isotype

IgG2b κ

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Description

  • This Anti-DNA G-quadruplex (G4) Antibody, clone 1H6 is validated for use in Immunocytochemistry, Immunohistochemistry (Paraffin), ELISA and Flow Cytometry for the detection of DNA G-quadruplex .

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MilliporeSigma

MABE1126MI

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Antigen:
DNA G-quadruplex (G4)

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
All species

Form:
Purified

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), ELISA, Flow Cytometry

Clone:
1H6

Conjugate:
Unconjugated

Immunogen:
KLH-conjugated G-quadruplex DNA derived from oligonucleotides with telomeric repeats.

Quantity:
100 μg

Research Discipline:
Epigenetics and Nuclear Function

Test Specificity:
Clone 1H6 binds both tetramolecular and unimolecular (intramolecular) DNA G-quadruplex (G4) structures without sequence specificity, while exhibiting significantly lower affinity toward tetramolecular RNA structure or a triplex DNA structure, and little to no affinity toward either non-G4 ssDNA or ddDNA. However, clone 1H6 does not seem to bind the [AGGG(TTAGGG)3] unimolecular G4 structure, indicating a broad selectivity toward many, but not all, DNA G4 structures (Henderson, A., et al. (2014). Nucleic Acids Res. 42(2):860-869).

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG2b κ

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MilliporeSigma™

MABE1130

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Antigen:
Hsp70/Hsp72

Classification:
Monoclonal

Concentration:
__

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Bovine, Human

Form:
Purified

Applications:
Western Blot

Clone:
2H9

Conjugate:
__

Immunogen:
Bovine skeletal muscle Hsp70/Hsp72.

Quantity:
100 μg

Research Discipline:
Epigenetics and Nuclear Function

Test Specificity:
__

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG1 κ

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MilliporeSigma™

MABE1132MI

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Antigen:
TET2

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Host Species:
Rat

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Purified

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
9F7

Conjugate:
Unconjugated

Immunogen:
His-tagged recombinant fragment from the region between DNA-binding and 2-oxoglutarate-binding domains of mouse TET2.

Quantity:
100 μg

Research Discipline:
Epigenetics & Nuclear Function

Test Specificity:
Clone 9F7 detected exogenously expressed TET2, but not TET1 or TET3, GST fusion (Bauer, C., et al. (2015). J. Biol. Chem. 290(8):4801-4812). Epitope region is present in all three murine TET2 spliced isoforms reported by UniProt (Q4JK59).

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG2a κ

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Fischer Scientific

MABE1138100

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Antigen:
BAF180

Classification:
Monoclonal

Concentration:
__

Host Species:
Rat

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
370.1.8C3

Conjugate:
Unconjugated

Immunogen:
GST-tagged recombinant fragment corresponding to 241 amino acids from the C-terminal half of human Protein polybromo-1 (BAF180).

Quantity:
100 μL

Research Discipline:
Epigenetics & Nuclear Function

Test Specificity:
Clone 370.1.8C3 is a rat monoclonal antibody that specifically detects human Protein Polybromo-1 (BAF180). It targets an epitope within 241 amino acids from the C-terminal half.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG2a κ