MABE633MI

MilliporeSigma™ Mouse anti-ELK1, Clone: 3H6D12,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABE633MI-Each-of-1 In Stock ₹ 42,677.33

MABE633MI - Each of 1

₹ 42,677.33

In Stock

Quantity

1

Base Price: ₹ 42,677.33

GST (18%): ₹ 7,681.919

Total Price: ₹ 50,359.249

Antigen

ELK1

Classification

Monoclonal

Formulation

Mouse monoclonal IgG1 ascitic fluid containing 0.03% sodium azide.

Gene Symbols

ELK1

Immunogen

Purified recombinant fragment of ELK1 expressed inE. coli.

Quantity

100 μL

Research Discipline

Epigenetics and Nuclear Function

Target Species

Human

Form

Ascites

Applications

Immunohistochemistry, Western Blot

Clone

3H6D12

Gene Accession No.

P19419

Host Species

Mouse

Purification Method

Unpurified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.

Isotype

IgG1

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Description

  • Specifically detects ELK1 clone: 3H6D12 in Human samples, and it is validated for Immunohistochemistry, Western Blotting ETS domain-containing protein Elk-1 (ELK1) is a family of member of ETS oncogene family and of the ternary complex factor (TCF) subfamily,which is located on chromosome Xp11.2 and stimulates transcription
  • binds to purine-rich DNA sequences
  • Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene
  • The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade
  • Elk1 is phosphorylated by MAP kinase pathways at a cluster of S/T motifs at its C terminus,It appears to be a direct target of activated MAP kinase
  • Biochemical studies indicate that Elk1 is a good substrate for MAP kinase, the kinetics of Elk1phosphorylation and activation correlate with MAP kinase activity, and interfering mutants of MAP kinase block Elk1 activation in vivo
  • More recent studies have shown that Elk1 is also a target of the Stress Activated Kinase SAPK/JNK
  • Phosphorylation of Elk1 has also been implicated in synaptic plasticity in the adult hippocampus.

Compare Similar Items

Show Difference

Img

MilliporeSigma™

MABE633MI

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Antigen:
ELK1

Classification:
Monoclonal

Formulation:
Mouse monoclonal IgG1 ascitic fluid containing 0.03% sodium azide.

Gene Symbols:
ELK1

Immunogen:
Purified recombinant fragment of ELK1 expressed inE. coli.

Quantity:
100 μL

Research Discipline:
Epigenetics and Nuclear Function

Target Species:
Human

Form:
Ascites

Applications:
Immunohistochemistry, Western Blot

Clone:
3H6D12

Gene Accession No.:
P19419

Host Species:
Mouse

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.

Isotype:
IgG1

Img

MilliporeSigma™

MABE636MI

--


Antigen:
monomethyl Histone H3 (Lys4)

Classification:
Monoclonal

Formulation:
Rabbit monoclonal in PBS with 1% BSA and 0.09% sodium azide.

Gene Symbols:
H3F3A; H3.3A; H3F3; PP781; H3F3B; H3.3B

Immunogen:
A linear peptide corresponding to human Histone H3 monomethylated at Lys4.

Quantity:
100 μg

Research Discipline:
Epigenetics and Nuclear Function

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
RM140

Gene Accession No.:
P84243

Host Species:
Rabbit

Purification Method:
Protein A Purfied

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

Isotype:
IgG

Img

MilliporeSigma™

MABE639MI

--


Antigen:
dimethyl Histone H3 (Lys36)

Classification:
Monoclonal

Formulation:
Rabbit monoclonal in PBS with 1% BSA and 0.09% sodium azide.

Gene Symbols:
H3F3A; H3.3A; H3F3; PP781; H3F3B; H3.3B

Immunogen:
A linear peptide corresponding to human Histone H3 dimethylated at Lys36.

Quantity:
100 μg

Research Discipline:
Epigenetics and Nuclear Function

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
RM141

Gene Accession No.:
P84243

Host Species:
Rabbit

Purification Method:
Protein A Purfied

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

Isotype:
IgG

Img

MilliporeSigma™

MABE640MI

--


Antigen:
trimethyl Histone H3 (Lys36)

Classification:
Monoclonal

Formulation:
Rabbit monoclonal in PBS with 1% BSA and 0.09% sodium azide.

Gene Symbols:
H3F3A; H3.3A; H3F3; PP781; H3F3B; H3.3B

Immunogen:
A linear peptide corresponding to human Histone H3 trimethylated at Lys36.

Quantity:
100 μg

Research Discipline:
Epigenetics and Nuclear Function

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
RM155

Gene Accession No.:
P84243

Host Species:
Rabbit

Purification Method:
Protein A Purfied

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

Isotype:
IgG