MABF1416MI
MilliporeSigma™ anti-TIGIT, APC, Clone: 1G9,
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABF1416MI-Each-of-1 | In Stock | ₹ 16,194.80 |
MABF1416MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,194.80
GST (18%): ₹ 2,915.064
Total Price: ₹ 19,109.864
Antigen
TIGIT
Classification
Monoclonal
Conjugate
APC
Gene Accession No.
P86176
Host Species
Mouse
Purification Method
Purified by size-exclusion chromatography
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
2°C to 8°C for one year from date of shipment protected from light; Do not freeze
Applications
Flow Cytometry
Clone
1G9
Formulation
Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols
Tigit
Immunogen
Proprietary immunogen
Quantity
25 μg
Research Discipline
Inflammation, Immunology
Target Species
Mouse
Form
Purified
Related Products
Description
- Specifically detects TIGIT Clone: 1G9 in Mouse samples, and it is validated for Flow Cytometry The 1G9 antibody reacts with mouse TIGIT (T cell Ig and ITIM domain), a 26kDa member of the CD28 receptor family which is reported to regulate T cell receptor (TCR) activation
- Within the CD28 family of receptors there are those which have co-stimulatory activity, such as CD28 and CTLA-4, as well as more recently identified receptors like TIGIT which are proposed to provide co-inhibitory signals
- TIGIT is expressed and upregulated on activated T cells, and is also expressed on memory and regulatory T cells
- Upon engagement by its ligands, CD112 and CD155, TIGIT signaling inhibits T cell proliferation and suppresses T cell responses, without triggering cell deletion
- A second inhibitory effect of TIGIT signaling is the generation of immunoregulatory dendritic cells, which secrete IL-10 and TGF-beta to further inhibit T cell function.The 1G9 antibody may be used for flow cytometric analysis of TIGIT, which is expressed at very high levels on T regulatory cells (Tregs) and activated conventional T cells, as well as memory T cells and NK cells.
Compare Similar Items
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Antigen: TIGIT
Classification: Monoclonal
Conjugate: APC
Gene Accession No.: P86176
Host Species: Mouse
Purification Method: Purified by size-exclusion chromatography
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: 2°C to 8°C for one year from date of shipment protected from light; Do not freeze
Applications: Flow Cytometry
Clone: 1G9
Formulation: Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols: Tigit
Immunogen: Proprietary immunogen
Quantity: 25 μg
Research Discipline: Inflammation, Immunology
Target Species: Mouse
Form: Purified
Antigen:
TIGIT
Classification:
Monoclonal
Conjugate:
APC
Gene Accession No.:
P86176
Host Species:
Mouse
Purification Method:
Purified by size-exclusion chromatography
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
2°C to 8°C for one year from date of shipment protected from light; Do not freeze
Applications:
Flow Cytometry
Clone:
1G9
Formulation:
Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols:
Tigit
Immunogen:
Proprietary immunogen
Quantity:
25 μg
Research Discipline:
Inflammation, Immunology
Target Species:
Mouse
Form:
Purified
Antigen: TIGIT
Classification: Monoclonal
Conjugate: APC
Gene Accession No.: P86176
Host Species: Mouse
Purification Method: Purified by size-exclusion chromatography
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: 2°C to 8°C for one year from date of shipment protected from light; Do not freeze
Applications: Flow Cytometry
Clone: 1G9
Formulation: Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols: Tigit
Immunogen: Proprietary immunogen
Quantity: 100 μg
Research Discipline: Inflammation, Immunology
Target Species: Mouse
Form: Purified
Antigen:
TIGIT
Classification:
Monoclonal
Conjugate:
APC
Gene Accession No.:
P86176
Host Species:
Mouse
Purification Method:
Purified by size-exclusion chromatography
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
2°C to 8°C for one year from date of shipment protected from light; Do not freeze
Applications:
Flow Cytometry
Clone:
1G9
Formulation:
Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols:
Tigit
Immunogen:
Proprietary immunogen
Quantity:
100 μg
Research Discipline:
Inflammation, Immunology
Target Species:
Mouse
Form:
Purified
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