MABF1499MI
MilliporeSigma™ CD117 (c-Kit), Rat, PE-Cy7, Clone: ACK2,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABF1499MI-Each-of-1 | In Stock | ₹ 27,509.25 |
MABF1499MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 27,509.25
GST (18%): ₹ 4,951.665
Total Price: ₹ 32,460.915
Antigen
CD117 (c-Kit)
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.
Gene Accession No.
P05532
Immunogen
Immunogen information for this antibody is proprietary information.
Quantity
100 μg
Research Discipline
Inflammation & Immunology
Target Species
Mouse
Form
Purified
Applications
Flow Cytometry
Clone
ACK2
Conjugate
PE-Cyanine7
Gene
Kit, SI
Host Species
Rat
Purification Method
Purified by size-exclusion chromatography
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt. Note: It is recommended to store the product undiluted at 2°-8°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The ACK2 antibody is specific for CD117, also called c-Kit, a 145kDa cytokine receptor important in the development of hematopoietic stem cells, in oogenesis, and for functional activity of immune cells such as NK and mast cells
- c-Kit binds to a ligand known as stem cell factor (SCF), or alternatively as mast cell growth factor
- Ligand binding promotes the activation (dimerization) and subsequent tyrosine kinase activity of the c-Kit receptor and triggers key survival, expansion and maturation signals during hematopoietic progenitor cell development
- Conversely, shedding of extracellular domain of c-Kit receptor is reported to induce inactivation or apoptosis within these cells
- The survival signaling activity of c-Kit confers a proto-oncogenic attribute to the receptor, as overexpression or mutations in this protein are associated with tumor development.The ACK2 antibody is widely utilized as a marker to identify hematopoietic progenitors, and to neutralize receptor-ligand binding in vitro and in vivo
- Please choose the appropriate format for each application
- In addition, the antibody is reported to be cross-reactive with rat c-Kit and is extensively published for use in this species.
Compare Similar Items
Show Difference
Antigen: CD117 (c-Kit)
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.
Gene Accession No.: P05532
Immunogen: Immunogen information for this antibody is proprietary information.
Quantity: 100 μg
Research Discipline: Inflammation & Immunology
Target Species: Mouse
Form: Purified
Applications: Flow Cytometry
Clone: ACK2
Conjugate: PE-Cyanine7
Gene: Kit, SI
Host Species: Rat
Purification Method: Purified by size-exclusion chromatography
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt. Note: It is recommended to store the product undiluted at 2°-8°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD117 (c-Kit)
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.
Gene Accession No.:
P05532
Immunogen:
Immunogen information for this antibody is proprietary information.
Quantity:
100 μg
Research Discipline:
Inflammation & Immunology
Target Species:
Mouse
Form:
Purified
Applications:
Flow Cytometry
Clone:
ACK2
Conjugate:
PE-Cyanine7
Gene:
Kit, SI
Host Species:
Rat
Purification Method:
Purified by size-exclusion chromatography
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt. Note: It is recommended to store the product undiluted at 2°-8°C and protected from prolonged exposure to light. Do not freeze.
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Immunogen: __
Quantity: __
Research Discipline: __
Target Species: __
Form: __
Applications: __
Clone: __
Conjugate: __
Gene: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Content And Storage: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Target Species:
__
Form:
__
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Content And Storage:
__
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Immunogen: __
Quantity: __
Research Discipline: __
Target Species: __
Form: __
Applications: __
Clone: __
Conjugate: __
Gene: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Content And Storage: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Target Species:
__
Form:
__
Applications:
__
Clone:
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Conjugate:
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Gene:
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Host Species:
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Purification Method:
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Regulatory Status:
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Primary or Secondary:
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Content And Storage:
__
Antigen: CD11c
Classification: Monoclonal
Concentration: __
Formulation: Purified Armenian Hamster monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Accession No.: Q9QXH4
Immunogen: Proprietary immunogen
Quantity: 25 μg
Research Discipline: Inflammation, Immunology
Target Species: Mouse
Form: Purified
Applications: Flow Cytometry
Clone: N418
Conjugate: Red Fluor 710
Gene: __
Host Species: Armenian Hamster
Purification Method: Purified by size-exclusion chromatography
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: 2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Antigen:
CD11c
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified Armenian Hamster monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Accession No.:
Q9QXH4
Immunogen:
Proprietary immunogen
Quantity:
25 μg
Research Discipline:
Inflammation, Immunology
Target Species:
Mouse
Form:
Purified
Applications:
Flow Cytometry
Clone:
N418
Conjugate:
Red Fluor 710
Gene:
__
Host Species:
Armenian Hamster
Purification Method:
Purified by size-exclusion chromatography
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze