MABN254725

VMAT1, Mouse anti-Mouse, Rat, Clone: N440/21, Millipore Sigma™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 MABN254725-Each-of-1 In Stock ₹ 16,456.61

MABN254725 - Each of 1

₹ 16,456.61

In Stock

Quantity

1

Base Price: ₹ 16,456.61

GST (18%): ₹ 2,962.19

Total Price: ₹ 19,418.80

Antigen

VMAT1

Classification

Monoclonal

Conjugate

Unconjugated

Gene Alias

Chromaffin granule amine transporter;Solute carrier family 18 member 1;Vesicular amine transporter 1;VAT1

Host Species

Mouse

Purification Method

Protein G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Clone N440/21 specifically detects Vesicular monoamine transporter 1 (VMAT1) and does not show reactivity with VMAT2. It targets an epitope with in 93 amino acids from the N-terminal first lumenal region.

Content And Storage

Stable for 1 year at 2-8°C from date of receipt.

Isotype

IgG1 κ

Applications

Western Blot

Clone

N440/21

Formulation

Purified mouse monoclonal antibody IgG1 in buffer containing 0.1M Tris-Glycine, 0.15M NaCl, 0.05% sodium azide, pH7.4 with 0.05% sodium azide.

Gene Symbols

Scl18a1;Vmat1

Immunogen

Recombinant fragment corresponding to 93 amino acids from the N-terminal first lumenal region of murine Vesicular amine transporter 1 (VMAT1).

Quantity

25 μL

Research Discipline

Neuroscience

Gene ID (Entrez)

NP_694694.1

Target Species

Rat, Mouse

Form

Purified

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Description

  • Anti-VMAT1, clone N440 21, Cat
  • No
  • MABN2547, is a highly specific mouse monoclonal antibody that targets Vesicular Monoamine Transporter 1 and has been tested for use in Western Blotting
  • Chromaffin granule amine transporter (UniProt: Q8R090; also known as Solute carrier family 18 member 1, Vesicular amine transporter 1, VMAT1, VAT1) is encoded by the Scl19a1 (also known as Vmat1) gene (Gene ID: 110877) in murine species
  • Vesicular monoamine transporters (VMATs) are involved in presynaptic storage and release of neurotransmitters
  • They are located in the presynaptic region and are involved in the transport of monoamines into storage vesicle, which are released upon arrival of an action potential
  • Two structurally related, but pharmacologically distinct, VMATs have been described (VMAT1 and VMAT2) that are encoded by separate genes
  • VMAT1 is a multi-pass membrane acidic glycoprotein that is found in both large dense-core vesicles and in small synaptic vesicles
  • It s both C- and N-terminal regions are located in the cytosolic side of the vesicle
  • VMAT1 is detected in adrenal medulla, and brain (at protein level)
  • In brain, specifically found in the medulla oblongata, pons, prefrontal cortex, striatum, dentate gyrus and hippocampus
  • VMAT1 is shown to play a key role in survival of hippocampal neurons and may contribute to neurocognitive deficits observed in neuropsychiatric disorders
  • (Ref.: Multani, PK., et al
  • (2013)
  • Neurosci
  • 232; 32-44).

Compare Similar Items

Show Difference

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Fischer Scientific

MABN254725

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Antigen:
VMAT1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Alias:
Chromaffin granule amine transporter;Solute carrier family 18 member 1;Vesicular amine transporter 1;VAT1

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone N440/21 specifically detects Vesicular monoamine transporter 1 (VMAT1) and does not show reactivity with VMAT2. It targets an epitope with in 93 amino acids from the N-terminal first lumenal region.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
N440/21

Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1M Tris-Glycine, 0.15M NaCl, 0.05% sodium azide, pH7.4 with 0.05% sodium azide.

Gene Symbols:
Scl18a1;Vmat1

Immunogen:
Recombinant fragment corresponding to 93 amino acids from the N-terminal first lumenal region of murine Vesicular amine transporter 1 (VMAT1).

Quantity:
25 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_694694.1

Target Species:
Rat, Mouse

Form:
Purified

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MABN25501MI

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Antigen:
GM2 ganglioside

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Alias:
Ganglioside GM2;GM2

Host Species:
Mouse

Purification Method:
Ligatrap

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
Clone GMB28 is a mouse monoclonal antibody that specifically detects GM2 ganglioside.

Content And Storage:
Stable for 1 year at 2 to 8°C from date of receipt.

Isotype:
IgM κ

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
GMB28

Formulation:
__

Gene Symbols:
__

Immunogen:
Purified GM2 ganglioside attached to Salmonella minnesota.

Quantity:
100 μL

Research Discipline:
Signaling

Gene ID (Entrez):
__

Target Species:
Human, Bovine

Form:
Purified

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MABN25502MI

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Antigen:
GM2 ganglioside

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Alias:
Ganglioside GM2;GM2

Host Species:
Mouse

Purification Method:
Ligatrap

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
Clone GMB28 is a mouse monoclonal antibody that specifically detects GM2 ganglioside.

Content And Storage:
Stable for 1 year at 2 to 8°C from date of receipt.

Isotype:
IgM κ

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
GMB28

Formulation:
__

Gene Symbols:
__

Immunogen:
Purified GM2 ganglioside attached to Salmonella minnesota.

Quantity:
25 μL

Research Discipline:
Signaling

Gene ID (Entrez):
__

Target Species:
Human, Bovine

Form:
Purified

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MABN25521MI

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Antigen:
alpha B-crystallin

Classification:
Monoclonal

Conjugate:
KLH

Gene Alias:
Alpha-crystallin B chain;Alpha(B)-crystallin;Heat shock protein beta-5;HspB5;Renal carcinoma antigen NY-REN-27;Rosenthal fiber component

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
Clone aB1788G7G6 is a mouse monoclonal antibody that detects Alpha(B)-crystallin. It targets an epitope within 21 amino acids within the N-terminal half.

Content And Storage:
Stable for 1 year at -20°C from date of receipt.

Isotype:
IgG1 κ

Applications:
ELISA, Immunofluorescence, Immunohistochemistry, Inhibition Assays, Western Blot

Clone:
aB1788G7G6

Formulation:
__

Gene Symbols:
CRYAB, CRYA2, HSOB5

Immunogen:
KLH-conjugated linear peptide corresponding to 21 amino acids from the N-terminal half of human Alpha(B)-crystallin.

Quantity:
100 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
__

Target Species:
Human, Mouse, Bovine, Monkey, Rat

Form:
Purified