MABS204725

MT-ND2, Mouse anti-Human, Clone: 9E12-1B3, Millipore Sigma™

Manufacturer: MilliporeSigma

Select a Size

Pack Size SKU Availability Price
Each of 1 MABS204725-Each-of-1 In Stock ₹ 16,456.61

MABS204725 - Each of 1

₹ 16,456.61

In Stock

Quantity

1

Base Price: ₹ 16,456.61

GST (18%): ₹ 2,962.19

Total Price: ₹ 19,418.80

Antigen

MT-ND2

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

Purified mouse monoclonal antibody IgG2a in buffer containing HEPES-Buffered Saline (150 mM NaCl, 15 mM HEPES, pH 7.2) with 0.02% sodium azide.

Gene Symbols

MT-ND2;MTND2;NADH2;ND2

Immunogen

Synthetic peptide corresponding to the N-terminus of human MT-ND2.

Quantity

25 μg

Research Discipline

Signaling

Test Specificity

Clone 9E12-1B3 detects NADH-ubiquinone oxidoreductase chain 2 (MT-ND2) in mitochondria from human cells. It targets an epitope within the N-terminal region.

Content And Storage

Stable for 1 year at 2-8°C from date of receipt.

Isotype

IgG2a κ

Applications

Western Blot

Clone

9E12-1B3

Dilution

Western Blotting Analysis: 2μg/mL from a representative lot detected MT-ND2 in mitochondria from human neonatal dermal fibroblasts and mitochondria from human neonatal dermal fibroblasts depleted of mtDNA (Courtesy of Michael F. Marusich, Ph.D., mAbDx, Inc., Eugene, OR USA).

Gene Alias

NADH-ubiquinone oxidoreductase chain 2;EC: 1.6.5.3;NADH dehydrogenase subunit 2;MT-ND2

Host Species

Mouse

Purification Method

Protein L

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Form

Purified

Description

  • Anti-MT-ND2, clone 9E12-1B3, Cat
  • No
  • MABS2047, is a mouse monoclonal antibody that detects NADH-ubiquinone oxidoreductase chain 2 and has been tested for use in Western Blotting
  • NADH-ubiquinone oxidoreductase chain 2 (UniProt: P03891; also known as EC: 1.6.5.3, NADH dehydrogenase subunit 2, MT-ND2) is encoded by the MT-ND2 (also known as MTND2, NADH2, ND2) gene (Gene ID: 4536) in human
  • MT-ND2 is a mitochondrial inner membrane protein that forms the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I)
  • It is believed to belong to the minimal assembly required for catalysis
  • Complex I functions in the transfer of electrons from NADH to the respiratory chain
  • The immediate electron acceptor for the enzyme is believed to be ubiquinone (Coenzyme Q10) that participates in the generation of a proton gradient, which is then used for ATP synthesis
  • Defects in MT-ND2 gene are known to cause of Leber hereditary optic neuropathy (LHON) that is a maternally inherited disease resulting in acute or subacute loss of central vision, due to optic nerve dysfunction
  • LHON results from primary mitochondrial DNA mutations affecting the respiratory chain complexes.

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MilliporeSigma

MABS204725

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Antigen:
MT-ND2

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
Purified mouse monoclonal antibody IgG2a in buffer containing HEPES-Buffered Saline (150 mM NaCl, 15 mM HEPES, pH 7.2) with 0.02% sodium azide.

Gene Symbols:
MT-ND2;MTND2;NADH2;ND2

Immunogen:
Synthetic peptide corresponding to the N-terminus of human MT-ND2.

Quantity:
25 μg

Research Discipline:
Signaling

Test Specificity:
Clone 9E12-1B3 detects NADH-ubiquinone oxidoreductase chain 2 (MT-ND2) in mitochondria from human cells. It targets an epitope within the N-terminal region.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG2a κ

Applications:
Western Blot

Clone:
9E12-1B3

Dilution:
Western Blotting Analysis: 2μg/mL from a representative lot detected MT-ND2 in mitochondria from human neonatal dermal fibroblasts and mitochondria from human neonatal dermal fibroblasts depleted of mtDNA (Courtesy of Michael F. Marusich, Ph.D., mAbDx, Inc., Eugene, OR USA).

Gene Alias:
NADH-ubiquinone oxidoreductase chain 2;EC: 1.6.5.3;NADH dehydrogenase subunit 2;MT-ND2

Host Species:
Mouse

Purification Method:
Protein L

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

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MABS2049-25

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Antigen:
Adenylate Cyclase 5

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
__

Gene Symbols:
Adcy5

Immunogen:
KLH-conjugated linear peptide corresponding to 20 amino acids from the cytoplasmic domain of murine adenylate cyclase V.

Quantity:
25 μg

Research Discipline:
Signaling

Test Specificity:
Clone 19D5.C1 detects Adnylate Cyclase 5 in murine, rat, and procine cells. It targets an epitope within 20 amino acids from the cytoplasmic domain.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
ELISA, Western Blot

Clone:
19D5.C1

Dilution:
__

Gene Alias:
__

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Mouse, Porcine, Rat

Form:
Purified

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MABS20531MI

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Antigen:
TFF3

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
__

Gene Symbols:
TFF3, ITF, TFI

Immunogen:
Recombinant human dimeric TFF3.

Quantity:
100 μg

Research Discipline:
Signaling

Test Specificity:
Clone TFF-286 is a mouse monoclonal antibody that detects human Trefoil factor 3 (TFF3).

Content And Storage:
Stable for 1 year at 2 to 8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
ELISA, Western Blot

Clone:
TFF-286

Dilution:
__

Gene Alias:
Trefoil factor 3;Intestinal trefoil factor;hITF;Polypeptide P1.B;hP1.B

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

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Antigen:
TFF3

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
__

Gene Symbols:
TFF3, ITF, TFI

Immunogen:
Recombinant human dimeric TFF3.

Quantity:
25 μg

Research Discipline:
Signaling

Test Specificity:
Clone TFF-286 is a mouse monoclonal antibody that detects human Trefoil factor 3 (TFF3).

Content And Storage:
Stable for 1 year at 2 to 8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
ELISA, Western Blot

Clone:
TFF-286

Dilution:
__

Gene Alias:
Trefoil factor 3;Intestinal trefoil factor;hITF;Polypeptide P1.B;hP1.B

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified