MABS807MI

MilliporeSigma™ Mouse anti-IKBKB, Clone: 10A2,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABS807MI-Each-of-1 In Stock ₹ 41,307.51

MABS807MI - Each of 1

₹ 41,307.51

In Stock

Quantity

1

Base Price: ₹ 41,307.51

GST (18%): ₹ 7,435.352

Total Price: ₹ 48,742.862

Antigen

IKBKB

Classification

Monoclonal

Formulation

Mouse monoclonal IgG1 ascitic fluid containing 0.03% sodium azide.

Gene Symbols

IKBKB; IKKB

Immunogen

Purified recombinant fragment of IKBKB expressed inE. coli.

Quantity

100 μL

Research Discipline

Signaling

Target Species

Human

Form

Ascites

Applications

Western Blot

Clone

10A2

Gene Accession No.

O14920

Host Species

Mouse

Purification Method

Unpurified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.

Isotype

IgG1

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Description

  • Specifically detects IKBKB clone: 10A2 in Human samples, and it is validated for Western Blotting Inhibitor of kappa light polypeptide gene enhancer in B-cells (IKBKB), also known as kinase beta or IKK2/IKKB, is a member of the IKK complex which is composed of IKK-alpha, IKK-beta, IKK-gamma and IKAP
  • Phosphorylation of I-Kappa-B on a serine residue by the IKK complex frees NF-kB from I-Kappa-B and marks it for degradation via ubiquination
  • IKK-beta has been shown to activate NF-kB and phosphorylate IKB-alpha and beta
  • Phosphorylation of 2 sites at the activation loop of IKK-beta is essential for activation of IKK by TNF and IL1
  • Once activated, IKK-beta autophosphorylates which in turn decreases IKK activity and prevents prolonged activation of the inflammatory response
  • Additionally, IKK-beta activity can also be regulated by MEKK-1.

Compare Similar Items

Show Difference

Img

MilliporeSigma™

MABS807MI

--


Antigen:
IKBKB

Classification:
Monoclonal

Formulation:
Mouse monoclonal IgG1 ascitic fluid containing 0.03% sodium azide.

Gene Symbols:
IKBKB; IKKB

Immunogen:
Purified recombinant fragment of IKBKB expressed inE. coli.

Quantity:
100 μL

Research Discipline:
Signaling

Target Species:
Human

Form:
Ascites

Applications:
Western Blot

Clone:
10A2

Gene Accession No.:
O14920

Host Species:
Mouse

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.

Isotype:
IgG1

Img

MilliporeSigma™

MABS808MI

--


Antigen:
GSK3 alpha

Classification:
Monoclonal

Formulation:
Mouse monoclonal IgG1 ascitic fluid containing 0.03% sodium azide.

Gene Symbols:
GSK3B

Immunogen:
Purified recombinant fragment of GSK3 alpha expressed inE. coli.

Quantity:
100 μL

Research Discipline:
Signaling

Target Species:
Human

Form:
Ascites

Applications:
Immunocytochemistry, Western Blot

Clone:
9D5G1

Gene Accession No.:
P49840

Host Species:
Mouse

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.

Isotype:
IgG1

Img

MilliporeSigma™

MABS809MI

--


Antigen:
JAK2

Classification:
Monoclonal

Formulation:
Mouse monoclonal IgG1 ascitic fluid containing 0.03% sodium azide.

Gene Symbols:
JAK2

Immunogen:
Purified recombinant fragment of JAK2 expressed inE. coli

Quantity:
100 μL

Research Discipline:
Signaling

Target Species:
Human

Form:
Ascites

Applications:
Western Blot

Clone:
1C1

Gene Accession No.:
O60674

Host Species:
Mouse

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.

Isotype:
IgG1

Img

MilliporeSigma™

MABS813MI

--


Antigen:
MAP2K2

Classification:
Monoclonal

Formulation:
Mouse monoclonal IgG1 ascitic fluid containing 0.03% sodium azide.

Gene Symbols:
MAP2K2; MEK2; MKK2; PRKMK2

Immunogen:
Purified recombinant fragment of human MAP2K2 expressed inE. coli.

Quantity:
100 μL

Research Discipline:
Signaling

Target Species:
Human, Mouse, Rat

Form:
Ascites

Applications:
Flow Cytometry

Clone:
7F5

Gene Accession No.:
P36507

Host Species:
Mouse

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.

Isotype:
IgG1