Epredia™ Lab Vision™ Factor XIII A Ab-1 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Description

• Detect factor XIII in both reduced and non-reduced forms
• This abtibody does not react with human Factor XIII B-chain or human Factor XII
• Factor XIII is a Β-globulin found in plasma and is composed of two subunits
• Factor XIII-A is the catalytic subunit and is a dimer of M.W
• 160 kDa
• Factor XIII is present in plasma as an alpha2Β2 heterodimer (M.W
• 320 kDa); whereas in platelets, only the α2 unit exists
• Factor XIIIa is a dermal dendrocyte marker and shows variable reaction with these types of tumors
• It can be used for histiocytic phenotyping and has been reported to mark capillary hemangiomas and tumors of the central nervous system
• Factor XIII has also been used with CD34 to differentiate between dermatofibroma and dermatofibrosarcoma protuberans
• Host Species: Mouse Clone: AC-1A1 Isotype: IgG1/κ Species Reactivity: Human
• Others not known
• Epitope: Not determined Immunogen: Recombinant protein corresponding to A-subunit of coagulation Factor XIII Molecular Weight: 160 kDa (unreduced dimmer); 80 kDa (reduced monomer) Positive Control: Recombinant human Factor XIII A-subunit; Capillary hemangioma, dermatofibroma and placenta Cellular Localization: Cytoplasmic and nuclear Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting