MS1248PABX

Epredia™ Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-3 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Manufacturer: Fischer Scientific

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Antigen

Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-3

Classification

Monoclonal

Concentration

1mg/mL

Host Species

Mouse

Quantity

200 μL

Primary or Secondary

Primary

Form

Concentrated

Applications

Immunofluorescence, Immunoprecipitation

Clone

L12B4

Conjugate

Unconjugated

Immunogen

Recombinant protein encoding NBF1 domain of human CFTR

Regulatory Status

RUO

Target Species

Human, Mouse, Rat

Isotype

IgG1

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Description

  • CFTR (cystic fibrosis transmembrane conductance regulator) is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain
  • It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates
  • The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts
  • CFTR is a valuable marker of human pancreatic duct cell development and differentiation
  • Host Species: Mouse Clone: L12B4 Isotype: IgG1 Species Reactivity: Human, Mouse and Rat
  • Others not known
  • Epitope: aa 386-412 Immunogen: Recombinant protein encoding NBF1 domain of human CFTR Molecular Weight: 165-170 kDa Positive Control: Pancreas Cellular Localization: Membrane Recommended for: Western Blotting (Not verified) Immunofluorescence Immunoprecipitation Note: USA: RUO; Int'l: RUO

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Fischer Scientific

MS1248PABX

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Antigen:
Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-3

Classification:
Monoclonal

Concentration:
1mg/mL

Host Species:
Mouse

Quantity:
200 μL

Primary or Secondary:
Primary

Form:
Concentrated

Applications:
Immunofluorescence, Immunoprecipitation

Clone:
L12B4

Conjugate:
Unconjugated

Immunogen:
Recombinant protein encoding NBF1 domain of human CFTR

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat

Isotype:
IgG1

Img

Fischer Scientific

MS126B

--


Antigen:
Involucrin Ab-1

Classification:
Monoclonal

Concentration:
200μg/mL

Host Species:
Mouse

Quantity:
1 mL

Primary or Secondary:
Primary

Form:
Concentrated

Applications:
ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
SY5

Conjugate:
Biotin

Immunogen:
Human keratinocytes involucrin

Regulatory Status:
RUO

Target Species:
Canine, Human, Non-human Primate, Porcine, Rat

Isotype:
IgG1

Img

Fischer Scientific

MS126B0

--


Antigen:
Involucrin Ab-1

Classification:
Monoclonal

Concentration:
200μg/mL

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Form:
Concentrated

Applications:
ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
SY5

Conjugate:
Biotin

Immunogen:
Human keratinocytes involucrin

Regulatory Status:
RUO

Target Species:
Canine, Human, Non-human Primate, Porcine, Rat

Isotype:
IgG1

Img

Fischer Scientific

MS126B1

--


Antigen:
Involucrin Ab-1

Classification:
Monoclonal

Concentration:
200μg/mL

Host Species:
Mouse

Quantity:
500 μL

Primary or Secondary:
Primary

Form:
Concentrated

Applications:
ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
SY5

Conjugate:
Biotin

Immunogen:
Human keratinocytes involucrin

Regulatory Status:
RUO

Target Species:
Canine, Human, Non-human Primate, Porcine, Rat

Isotype:
IgG1