MS1834R1

Epredia™ Lab Vision™ Perforin Ab-2, Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Perforin Ab-2

Classification

Monoclonal

Conjugate

Unconjugated

Immunogen

Recombinant protein corresponding to C-terminal region of human perforin

Regulatory Status

IVD

Primary or Secondary

Primary

Form

Prediluted

Applications

Immunohistochemistry (Paraffin)

Clone

5B10

Host Species

Mouse

Quantity

1 mL

Research Discipline

T-Cell

Target Species

Human

Isotype

IgG1

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Description

  • Perforin is a potent cytolytic pore-forming protein
  • It is a specific marker of functionally active cytotoxic T-lymphocytes (CTLs) and natural killer (NK) cells
  • Perforin is a key effector mechanisms in T cell-mediated cytotoxicity
  • It mediates cytolysis of target cells by membrane damage and apoptosis
  • Host Species: Mouse Clone: 5B10 Isotype: IgG1 Species Reactivity: Human
  • Others not known
  • Epitope: C-terminal Immunogen: Recombinant protein corresponding to C-terminal region of human perforin Molecular Weight: 70kDa Positive Control: Lymphoma Cellular Localization: Granular and cytoplasmic Recommended for: Immunohistochemistry (Formalin/paraffin) General References: 1
  • Lichtenheld M G, et al
  • (1988) Nature, 335:448-451
  • 2
  • Hameed A, et
  • al
  • American Journal of Pathology, 1992, 140(5):1025-30.

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Fischer Scientific

MS1834R1

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Antigen:
Perforin Ab-2

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
Recombinant protein corresponding to C-terminal region of human perforin

Regulatory Status:
IVD

Primary or Secondary:
Primary

Form:
Prediluted

Applications:
Immunohistochemistry (Paraffin)

Clone:
5B10

Host Species:
Mouse

Quantity:
1 mL

Research Discipline:
T-Cell

Target Species:
Human

Isotype:
IgG1

Img

Fischer Scientific

MS1834R7

--


Antigen:
Perforin Ab-2

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
Recombinant protein corresponding to C-terminal region of human perforin

Regulatory Status:
IVD

Primary or Secondary:
Primary

Form:
Prediluted

Applications:
Immunohistochemistry (Paraffin)

Clone:
5B10

Host Species:
Mouse

Quantity:
7 mL

Research Discipline:
T-Cell

Target Species:
Human

Isotype:
IgG1

Img

Fischer Scientific

MS1834S

--


Antigen:
Perforin Ab-2

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
Recombinant protein corresponding to C-terminal region of human perforin

Regulatory Status:
IVD

Primary or Secondary:
Primary

Form:
Concentrated

Applications:
Immunohistochemistry (Paraffin)

Clone:
5B10

Host Species:
Mouse

Quantity:
1 mL

Research Discipline:
T-Cell

Target Species:
Human

Isotype:
IgG1

Img

Fischer Scientific

MS1834S0

--


Antigen:
Perforin Ab-2

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
Recombinant protein corresponding to C-terminal region of human perforin

Regulatory Status:
IVD

Primary or Secondary:
Primary

Form:
Concentrated

Applications:
Immunohistochemistry (Paraffin)

Clone:
5B10

Host Species:
Mouse

Quantity:
100 μL

Research Discipline:
T-Cell

Target Species:
Human

Isotype:
IgG1