At least five CD1 genes (CD1a, b, c, d, and e) have been identified
CD1 is expressed on cortical thymocytes, Langerhans cells, and dendritic cells
It is absent on mature peripheral blood T cells but intracytoplasmic expression is detected on activated T lymphocytes
CD1 proteins have been demonstrated to restrict T-cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation
Host Species: Mouse Clone: O10 Isotype: IgG1/κ Species Reactivity: Human