MS269P
Epidermal Growth Factor Receptor/EGFR Ab-2 Mouse Monoclonal Antibody, Epredia™
Manufacturer: Fischer Scientific
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Antigen
Epidermal Growth Factor Receptor/EGFR Ab-2
Classification
Monoclonal
Concentration
200μg/mL
Host Species
Mouse
Quantity
1 mL
Research Discipline
EGFR Family
Target Species
Human, Non-human Primate
Isotype
IgG1
Applications
Immunoprecipitation
Clone
225
Conjugate
Unconjugated
Immunogen
Purified EGFR from A431 cells
Regulatory Status
RUO
Primary or Secondary
Primary
Form
Concentrated
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Description
- EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4
- It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin
- EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium
- It is predominantly present in squamous cell carcinomas
- Host Species: Mouse Clone: 225 Isotype: IgG1 Species Reactivity: Human, Chimpanzee and Monkey
- Does not react with mouse and rat
- Others not known
- Epitope: Extracellular domain Immunogen: Purified EGFR from A431 cells Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant) Positive Control: A431 cells Cellular Localization: Membrane Recommended for: Immunoprecipitation (Native only) Blocks EGF/TGFα-Induced Activation of EGFR Arrests Tumor Growth in vivo Inhibits Binding of Ab-1 (clone 528) to EGFR Note: USA: RUO; Int'l: RUO
Compare Similar Items
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Antigen: Epidermal Growth Factor Receptor/EGFR Ab-2
Classification: Monoclonal
Concentration: 200μg/mL
Host Species: Mouse
Quantity: 1 mL
Research Discipline: EGFR Family
Target Species: Human, Non-human Primate
Isotype: IgG1
Applications: Immunoprecipitation
Clone: 225
Conjugate: Unconjugated
Immunogen: Purified EGFR from A431 cells
Regulatory Status: RUO
Primary or Secondary: Primary
Form: Concentrated
Antigen:
Epidermal Growth Factor Receptor/EGFR Ab-2
Classification:
Monoclonal
Concentration:
200μg/mL
Host Species:
Mouse
Quantity:
1 mL
Research Discipline:
EGFR Family
Target Species:
Human, Non-human Primate
Isotype:
IgG1
Applications:
Immunoprecipitation
Clone:
225
Conjugate:
Unconjugated
Immunogen:
Purified EGFR from A431 cells
Regulatory Status:
RUO
Primary or Secondary:
Primary
Form:
Concentrated
Antigen: Epidermal Growth Factor Receptor/EGFR Ab-2
Classification: Monoclonal
Concentration: 200μg/mL
Host Species: Mouse
Quantity: 100 μL
Research Discipline: EGFR Family
Target Species: Human, Non-human Primate
Isotype: IgG1
Applications: Immunoprecipitation
Clone: 225
Conjugate: Unconjugated
Immunogen: Purified EGFR from A431 cells
Regulatory Status: RUO
Primary or Secondary: Primary
Form: Concentrated
Antigen:
Epidermal Growth Factor Receptor/EGFR Ab-2
Classification:
Monoclonal
Concentration:
200μg/mL
Host Species:
Mouse
Quantity:
100 μL
Research Discipline:
EGFR Family
Target Species:
Human, Non-human Primate
Isotype:
IgG1
Applications:
Immunoprecipitation
Clone:
225
Conjugate:
Unconjugated
Immunogen:
Purified EGFR from A431 cells
Regulatory Status:
RUO
Primary or Secondary:
Primary
Form:
Concentrated
Antigen: Epidermal Growth Factor Receptor/EGFR Ab-2
Classification: Monoclonal
Concentration: 200μg/mL
Host Species: Mouse
Quantity: 500 μL
Research Discipline: EGFR Family
Target Species: Human, Non-human Primate
Isotype: IgG1
Applications: Immunoprecipitation
Clone: 225
Conjugate: Unconjugated
Immunogen: Purified EGFR from A431 cells
Regulatory Status: RUO
Primary or Secondary: Primary
Form: Concentrated
Antigen:
Epidermal Growth Factor Receptor/EGFR Ab-2
Classification:
Monoclonal
Concentration:
200μg/mL
Host Species:
Mouse
Quantity:
500 μL
Research Discipline:
EGFR Family
Target Species:
Human, Non-human Primate
Isotype:
IgG1
Applications:
Immunoprecipitation
Clone:
225
Conjugate:
Unconjugated
Immunogen:
Purified EGFR from A431 cells
Regulatory Status:
RUO
Primary or Secondary:
Primary
Form:
Concentrated
Antigen: Epidermal Growth Factor Receptor/EGFR Ab-2
Classification: Monoclonal
Concentration: 1mg/mL
Host Species: Mouse
Quantity: 100 μL
Research Discipline: EGFR Family
Target Species: Human, Non-human Primate
Isotype: IgG1
Applications: Immunoprecipitation
Clone: 225
Conjugate: Unconjugated
Immunogen: Purified EGFR from A431 cells
Regulatory Status: RUO
Primary or Secondary: Primary
Form: Concentrated
Antigen:
Epidermal Growth Factor Receptor/EGFR Ab-2
Classification:
Monoclonal
Concentration:
1mg/mL
Host Species:
Mouse
Quantity:
100 μL
Research Discipline:
EGFR Family
Target Species:
Human, Non-human Primate
Isotype:
IgG1
Applications:
Immunoprecipitation
Clone:
225
Conjugate:
Unconjugated
Immunogen:
Purified EGFR from A431 cells
Regulatory Status:
RUO
Primary or Secondary:
Primary
Form:
Concentrated