CA19-9/Sialyl Lewisa (GI Tumor Marker) Ab-1 Mouse Monoclonal Antibody, Epredia™

Description

• Mucin glycoprotein is a sialyl Lewis a structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewis a and/or Lewis b blood group antigens
• In normal tissues, sialyl Lewis a antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands
• Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas
• Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery
• When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings
• Host Species: Mouse Clone: 121SLE Isotype: IgM Species Reactivity: Human
• Does not react with rat
• Others not tested
• Immunogen: Mucins from ovarian cyst Molecular Weight: >400kDa Positive Control: Colon CA Cellular Localization: Cytoplasmic Recommended for: Immunohistochemistry (Formalin/paraffin)