MS391S0

Epredia™ Lab Vision™ Estrogen Receptor Ab-12, Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Estrogen Receptor Ab-12

Classification

Monoclonal

Conjugate

Unconjugated

Immunogen

Recombinant full length estrogen receptor protein

Quantity

100 μL

Research Discipline

Steroids Hormones and Growth Factors

Target Species

Human, Rat

Isotype

IgG1

Applications

Immunoprecipitation

Clone

6F11

Host Species

Mouse

Purification Method

MCF-7 cells, breast CA

Regulatory Status

RUO

Primary or Secondary

Primary

Form

Concentrated

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Description

  • Description The ER gene consists of more than 140kb of genomic DNA divided into 8 exons and is translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition
  • The ER is an important regulator of growth and differentiation in the mammary gland
  • Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g
  • tamoxifen) therapy
  • Host Species: Mouse Clone: 6F11 Isotype: IgG1 Species Reactivity: Human and Rat
  • Others not known
  • Immunogen: Recombinant full-length estrogen receptor protein Molecular Weight: 67 kDa Positive Control: MCF-7 cells, Breast CA Cellular Localization: Nuclear Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Immunoprecipitation (Denatured verified) Note: USA: RUO; Int'l: RUO

Compare Similar Items

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Fischer Scientific

MS391S0

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Antigen:
Estrogen Receptor Ab-12

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
Recombinant full length estrogen receptor protein

Quantity:
100 μL

Research Discipline:
Steroids Hormones and Growth Factors

Target Species:
Human, Rat

Isotype:
IgG1

Applications:
Immunoprecipitation

Clone:
6F11

Host Species:
Mouse

Purification Method:
MCF-7 cells, breast CA

Regulatory Status:
RUO

Primary or Secondary:
Primary

Form:
Concentrated

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MS391S1

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Antigen:
Estrogen Receptor Ab-12

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
Recombinant full length estrogen receptor protein

Quantity:
500 μL

Research Discipline:
Steroids Hormones and Growth Factors

Target Species:
Human, Rat

Isotype:
IgG1

Applications:
Immunoprecipitation

Clone:
6F11

Host Species:
Mouse

Purification Method:
MCF-7 cells, breast CA

Regulatory Status:
RUO

Primary or Secondary:
Primary

Form:
Concentrated

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Antigen:
Neurotrophin Receptor/NGF-Receptor (p75superscriptNGFRsuperscript) Ab-1

Classification:
Monoclonal

Conjugate:
Biotin

Immunogen:
NGFR from A875 melanoma cells

Quantity:
1 mL

Research Discipline:
Neuroscience

Target Species:
Feline, Ferret, Human, Non-human Primate, Rabbit

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
NGFR5

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Primary or Secondary:
Primary

Form:
Concentrated

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Antigen:
Neurotrophin Receptor/NGF-Receptor (p75superscriptNGFRsuperscript) Ab-1

Classification:
Monoclonal

Conjugate:
Biotin

Immunogen:
NGFR from A875 melanoma cells

Quantity:
100 μL

Research Discipline:
Neuroscience

Target Species:
Feline, Ferret, Human, Non-human Primate, Rabbit

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
NGFR5

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Primary or Secondary:
Primary

Form:
Concentrated