MS457S
Epredia™ Lab Vision™ CD8 Ab-1, Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD8 Ab-1
Classification
Monoclonal
Conjugate
Unconjugated
Immunogen
A 13 amino acid synthetic peptide from the C-terminal cytoplasmic domain of alpha chain of human CD8 molecule
Regulatory Status
IVD
Primary or Secondary
Primary
Form
Concentrated
Applications
Immunohistochemistry (Paraffin)
Clone
C8/144B
Host Species
Mouse
Quantity
1 mL
Research Discipline
T-Cell
Target Species
Human
Isotype
IgG2a κ
Related Products
Description
- CD8 molecule consists of two chains, termed α and Β chain, which are expressed as a disulphide-α β heterdimer or as an alpha α homodimer on T cell subset (cytotoxic/suppressor T cells), thymocytes and NK cells
- The majority of CD8+ Tcells expresses CD8 as αβheterodimer
- CD8 functions as a coreceptor in concert with TCR for binding the MHC class I/peptide complex
- The HIV-2 envelope glycoprotein binds CD8 α chain (but not Β chain)
- Host Species: Mouse Clone: C8/144B Isotype: IgG1/κ Species Reactivity: Human
- Does not react with rat
- Others not known
- Epitope: C-terminal Immunogen: A 13 amino acid synthetic peptide from the C-terminal cytoplasmic domain of α-chain of human CD8 molecule Molecular Weight: 32 kDa Positive Control: Lymph node or tonsil Cellular Localization: Membrane Recommended for: Immunohistochemistry (Formalin/paraffin) General References: 1
- Mason DY, et
- al
- Journal of Clinical Pathology, 1992, 45(12):1084-8.
Compare Similar Items
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Antigen: CD8 Ab-1
Classification: Monoclonal
Conjugate: Unconjugated
Immunogen: A 13 amino acid synthetic peptide from the C-terminal cytoplasmic domain of alpha chain of human CD8 molecule
Regulatory Status: IVD
Primary or Secondary: Primary
Form: Concentrated
Applications: Immunohistochemistry (Paraffin)
Clone: C8/144B
Host Species: Mouse
Quantity: 1 mL
Research Discipline: T-Cell
Target Species: Human
Isotype: IgG2a κ
Antigen:
CD8 Ab-1
Classification:
Monoclonal
Conjugate:
Unconjugated
Immunogen:
A 13 amino acid synthetic peptide from the C-terminal cytoplasmic domain of alpha chain of human CD8 molecule
Regulatory Status:
IVD
Primary or Secondary:
Primary
Form:
Concentrated
Applications:
Immunohistochemistry (Paraffin)
Clone:
C8/144B
Host Species:
Mouse
Quantity:
1 mL
Research Discipline:
T-Cell
Target Species:
Human
Isotype:
IgG2a κ
Antigen: CD8 Ab-1
Classification: Monoclonal
Conjugate: Unconjugated
Immunogen: A 13 amino acid synthetic peptide from the C-terminal cytoplasmic domain of alpha chain of human CD8 molecule
Regulatory Status: IVD
Primary or Secondary: Primary
Form: Concentrated
Applications: Immunohistochemistry (Formalin/Paraffin)
Clone: C8/144B
Host Species: Mouse
Quantity: 100 μL
Research Discipline: T-Cell
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD8 Ab-1
Classification:
Monoclonal
Conjugate:
Unconjugated
Immunogen:
A 13 amino acid synthetic peptide from the C-terminal cytoplasmic domain of alpha chain of human CD8 molecule
Regulatory Status:
IVD
Primary or Secondary:
Primary
Form:
Concentrated
Applications:
Immunohistochemistry (Formalin/Paraffin)
Clone:
C8/144B
Host Species:
Mouse
Quantity:
100 μL
Research Discipline:
T-Cell
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD8 Ab-1
Classification: Monoclonal
Conjugate: Unconjugated
Immunogen: A 13 amino acid synthetic peptide from the C-terminal cytoplasmic domain of alpha chain of human CD8 molecule
Regulatory Status: IVD
Primary or Secondary: Primary
Form: Concentrated
Applications: Immunohistochemistry (Paraffin)
Clone: C8/144B
Host Species: Mouse
Quantity: 500 μL
Research Discipline: T-Cell
Target Species: Human
Isotype: IgG2a κ
Antigen:
CD8 Ab-1
Classification:
Monoclonal
Conjugate:
Unconjugated
Immunogen:
A 13 amino acid synthetic peptide from the C-terminal cytoplasmic domain of alpha chain of human CD8 molecule
Regulatory Status:
IVD
Primary or Secondary:
Primary
Form:
Concentrated
Applications:
Immunohistochemistry (Paraffin)
Clone:
C8/144B
Host Species:
Mouse
Quantity:
500 μL
Research Discipline:
T-Cell
Target Species:
Human
Isotype:
IgG2a κ
Antigen: CD155 Ab-1
Classification: Monoclonal
Conjugate: Biotin
Immunogen: HeLa cells
Regulatory Status: RUO
Primary or Secondary: Primary
Form: Concentrated
Applications: Immunofluorescence
Clone: D171
Host Species: Mouse
Quantity: 1 mL
Research Discipline: Cell Adhesion
Target Species: Human, Non-human Primate
Isotype: IgG1
Antigen:
CD155 Ab-1
Classification:
Monoclonal
Conjugate:
Biotin
Immunogen:
HeLa cells
Regulatory Status:
RUO
Primary or Secondary:
Primary
Form:
Concentrated
Applications:
Immunofluorescence
Clone:
D171
Host Species:
Mouse
Quantity:
1 mL
Research Discipline:
Cell Adhesion
Target Species:
Human, Non-human Primate
Isotype:
IgG1