MS489S

Epredia™ Lab Vision™ Cytokeratin 17 Ab-1, Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Cytokeratin 17 Ab-1

Classification

Monoclonal

Conjugate

Unconjugated

Immunogen

Keratin preparation from rat enterocytes

Quantity

1 mL

Research Discipline

Cytoskeletal Protein

Target Species

Human, Rat

Isotype

IgG2b κ

Applications

Immunofluorescence, Immunohistochemistry (Paraffin)

Clone

E3

Host Species

Mouse

Purification Method

Squamous cell CA, skin

Regulatory Status

IVD

Primary or Secondary

Primary

Form

Concentrated

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Description

  • The type I keratin 17 (K17) shows a peculiar localization in human epithelial appendages including hair follicles, which undergo a growth cycle throughout adult life
  • Additionally K17 is induced, along with K6 and K16, early after acute injury to human skin
  • Predominant expression of K17 and the frequent expression of K8 and K19, with little K6/K16 and K1/K10 expression are the characteristic features of basal cell carcinomas (BCC), suggesting that BCC is differentiated towards undifferentiated follicular epithelia, most probably hair bulge cells
  • Host Species: Mouse Clone: E3 Isotype: IgG2b/κ Species Reactivity: Human and Rat
  • Others not known
  • Epitope: Not determined Immunogen: Cytokeratin preparation from rat enterocytes Molecular Weight: 46 kDa Positive Control: Squamous cell CA, Skin Cellular Localization: Cytoplasmic Recommended for: Immunohistochemistry (Formalin/paraffin) Immunofluorescence

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Fischer Scientific

MS489S

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Antigen:
Cytokeratin 17 Ab-1

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
Keratin preparation from rat enterocytes

Quantity:
1 mL

Research Discipline:
Cytoskeletal Protein

Target Species:
Human, Rat

Isotype:
IgG2b κ

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
E3

Host Species:
Mouse

Purification Method:
Squamous cell CA, skin

Regulatory Status:
IVD

Primary or Secondary:
Primary

Form:
Concentrated

Img

Fischer Scientific

MS489S0

--


Antigen:
Cytokeratin 17 Ab-1

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
Keratin preparation from rat enterocytes

Quantity:
100 μL

Research Discipline:
Cytoskeletal Protein

Target Species:
Human, Rat

Isotype:
IgG2b κ

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
E3

Host Species:
Mouse

Purification Method:
Squamous cell CA, skin

Regulatory Status:
IVD

Primary or Secondary:
Primary

Form:
Concentrated

Img

Fischer Scientific

MS489S1

--


Antigen:
Cytokeratin 17 Ab-1

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
Keratin preparation from rat enterocytes

Quantity:
500 μL

Research Discipline:
Cytoskeletal Protein

Target Species:
Human, Rat

Isotype:
IgG2b κ

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
E3

Host Species:
Mouse

Purification Method:
Squamous cell CA, skin

Regulatory Status:
IVD

Primary or Secondary:
Primary

Form:
Concentrated

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Fischer Scientific

MS567B

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Antigen:
MMP-2 (72kDa Collagenase IV) Ab-1

Classification:
Monoclonal

Conjugate:
Biotin

Immunogen:
N-terminal peptide APSPIIKFPGD-VAPKTDK of procollagenase IV

Quantity:
1 mL

Research Discipline:
Proteases And Inhibitors

Target Species:
Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
CA-4001 or CA719E3C

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Primary or Secondary:
Primary

Form:
Concentrated