MS660P
p170/p-Glycoprotein/MDR Ab-2 Mouse Monoclonal Antibody, Epredia™
Manufacturer: Fischer Scientific
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Antigen
p170/p-Glycoprotein/MDR Ab-2
Classification
Monoclonal
Concentration
200μg/mL
Host Species
Mouse
Quantity
1 mL
Research Discipline
Cancer and Tumor Biology
Target Species
Hamster, Human
Isotype
IgG1
Applications
Immunofluorescence, Western Blot
Clone
F4
Conjugate
Unconjugated
Immunogen
Human and hamster drug-resistant viable cells followed by crude plasma membranes
Regulatory Status
RUO
Primary or Secondary
Primary
Form
Concentrated
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Description
- Multi-drug resistance(MDR) associated p-glycoprotein (p170) causes resistance to various drugs in a number of cancer patients
- It exists in a soluble and membrane associated form
- Soluble P-glycoprotein is detected in extracellular fluids of cancer patients, such as malignant ascites and serum
- The Mr of soluble P-glycoprotein is the same as that of membrane bound P-glycoprotein
- Host Species: Mouse Clone: F4 Isotype: IgG1 Species Reactivity: Human, Chinese Hamster
- Does not react with mouse
- Others not known
- Epitope: Extracellular amino terminal half
- This epitope is resistant to formalin fixation and periodate oxidation and is different from those of other commonly known MAbs to p-glycoprotein, such as C219, JSB-1, and MRK16, which recognize an intracellular and extracellular epitope of p-glycoprotein, respectively
- Immunogen: Human and hamster drug-resistant viable cells followed by crude plasma membranes Molecular Weight: 170kDa Positive Control: Drug-resistant cells, Kidney or breast CA Cellular Localization: Membrane Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Immunofluorescence Flow Cytometry (Fixed cells only) Note: USA: RUO; Int'l: RUO
Compare Similar Items
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Antigen: p170/p-Glycoprotein/MDR Ab-2
Classification: Monoclonal
Concentration: 200μg/mL
Host Species: Mouse
Quantity: 1 mL
Research Discipline: Cancer and Tumor Biology
Target Species: Hamster, Human
Isotype: IgG1
Applications: Immunofluorescence, Western Blot
Clone: F4
Conjugate: Unconjugated
Immunogen: Human and hamster drug-resistant viable cells followed by crude plasma membranes
Regulatory Status: RUO
Primary or Secondary: Primary
Form: Concentrated
Antigen:
p170/p-Glycoprotein/MDR Ab-2
Classification:
Monoclonal
Concentration:
200μg/mL
Host Species:
Mouse
Quantity:
1 mL
Research Discipline:
Cancer and Tumor Biology
Target Species:
Hamster, Human
Isotype:
IgG1
Applications:
Immunofluorescence, Western Blot
Clone:
F4
Conjugate:
Unconjugated
Immunogen:
Human and hamster drug-resistant viable cells followed by crude plasma membranes
Regulatory Status:
RUO
Primary or Secondary:
Primary
Form:
Concentrated
Antigen: p170/p-Glycoprotein/MDR Ab-2
Classification: Monoclonal
Concentration: 200μg/mL
Host Species: Mouse
Quantity: 500 μL
Research Discipline: Cancer and Tumor Biology
Target Species: Hamster, Human
Isotype: IgG1
Applications: Immunofluorescence, Western Blot
Clone: F4
Conjugate: Unconjugated
Immunogen: Human and hamster drug-resistant viable cells followed by crude plasma membranes
Regulatory Status: RUO
Primary or Secondary: Primary
Form: Concentrated
Antigen:
p170/p-Glycoprotein/MDR Ab-2
Classification:
Monoclonal
Concentration:
200μg/mL
Host Species:
Mouse
Quantity:
500 μL
Research Discipline:
Cancer and Tumor Biology
Target Species:
Hamster, Human
Isotype:
IgG1
Applications:
Immunofluorescence, Western Blot
Clone:
F4
Conjugate:
Unconjugated
Immunogen:
Human and hamster drug-resistant viable cells followed by crude plasma membranes
Regulatory Status:
RUO
Primary or Secondary:
Primary
Form:
Concentrated
Antigen: p170/p-Glycoprotein/MDR Ab-2
Classification: Monoclonal
Concentration: 1mg/mL
Host Species: Mouse
Quantity: 100 μL
Research Discipline: Cancer and Tumor Biology
Target Species: Hamster, Human
Isotype: IgG1
Applications: Immunofluorescence, Western Blot
Clone: F4
Conjugate: Unconjugated
Immunogen: Human and hamster drug-resistant viable cells followed by crude plasma membranes
Regulatory Status: RUO
Primary or Secondary: Primary
Form: Concentrated
Antigen:
p170/p-Glycoprotein/MDR Ab-2
Classification:
Monoclonal
Concentration:
1mg/mL
Host Species:
Mouse
Quantity:
100 μL
Research Discipline:
Cancer and Tumor Biology
Target Species:
Hamster, Human
Isotype:
IgG1
Applications:
Immunofluorescence, Western Blot
Clone:
F4
Conjugate:
Unconjugated
Immunogen:
Human and hamster drug-resistant viable cells followed by crude plasma membranes
Regulatory Status:
RUO
Primary or Secondary:
Primary
Form:
Concentrated
Antigen: p170/p-Glycoprotein/MDR Ab-2
Classification: Monoclonal
Concentration: 1mg/mL
Host Species: Mouse
Quantity: 200 μL
Research Discipline: Cancer and Tumor Biology
Target Species: Hamster, Human
Isotype: IgG1
Applications: Immunofluorescence, Western Blot
Clone: F4
Conjugate: Unconjugated
Immunogen: Human and hamster drug-resistant viable cells followed by crude plasma membranes
Regulatory Status: RUO
Primary or Secondary: Primary
Form: Concentrated
Antigen:
p170/p-Glycoprotein/MDR Ab-2
Classification:
Monoclonal
Concentration:
1mg/mL
Host Species:
Mouse
Quantity:
200 μL
Research Discipline:
Cancer and Tumor Biology
Target Species:
Hamster, Human
Isotype:
IgG1
Applications:
Immunofluorescence, Western Blot
Clone:
F4
Conjugate:
Unconjugated
Immunogen:
Human and hamster drug-resistant viable cells followed by crude plasma membranes
Regulatory Status:
RUO
Primary or Secondary:
Primary
Form:
Concentrated