Epredia™ Lab Vision™ CD10/CALLA (Neutral Endopeptidase) Ab-2, Mouse Monoclonal Antibody

Description

• CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA), is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides
• CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML)
• It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue
• CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells
• Host Species: Mouse Clone: 56C6 Isotype: IgG1 Species Reactivity: Human and Rat
• Others not tested
• Epitope: Extracellular Immunogen: Recombinant external domain of CD10 protein Molecular Weight: 100kDa Positive Control: Small intestine Cellular Localization: Membrane Recommended for: Immunohistochemistry (Formalin/paraffin)