MS800R1
Tyrosinase Ab-1 Mouse Monoclonal Antibody, Epredia™
Manufacturer: Fischer Scientific
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Antigen
Tyrosinase Ab-1
Classification
Monoclonal
Conjugate
Unconjugated
Host Species
Mouse
Quantity
1 mL
Research Discipline
Cancer and Tumor Biology
Target Species
Canine, Feline, Human
Isotype
IgG2a
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone
T311
Formulation
Ready-to-use format
Immunogen
Recombinant tyrosinase protein
Regulatory Status
IVD
Primary or Secondary
Primary
Form
Prediluted
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Description
- Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone
- Mutations of the tyrosinase gene occur in various forms of albinism
- Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients
- Host Species: Mouse Clone: T311 Isotype: IgG2a Species Reactivity: Human, Dog and Cat
- Weakly cross-reacts with Mouse
- Others not known
- Epitope: aa 1-433 Immunogen: Recombinant tyrosinase protein Molecular Weight: 70-80kDa Positive Control: Melanoma cell lines and Melanoma Cellular Localization: Cytoplasmic Ab-1 shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75
- Staining of melanomas with Ab-1 showed tyrosinase in melanotic as well as amelanotic variants
- Ab-1 is a useful marker for melanocytes and melanomas
- Occasionally a minor band at 55kDa is also detected in Western Blotting Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Immunofluorescence Immunocytology
Compare Similar Items
Show Difference
Antigen: Tyrosinase Ab-1
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 1 mL
Research Discipline: Cancer and Tumor Biology
Target Species: Canine, Feline, Human
Isotype: IgG2a
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: T311
Formulation: Ready-to-use format
Immunogen: Recombinant tyrosinase protein
Regulatory Status: IVD
Primary or Secondary: Primary
Form: Prediluted
Antigen:
Tyrosinase Ab-1
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
1 mL
Research Discipline:
Cancer and Tumor Biology
Target Species:
Canine, Feline, Human
Isotype:
IgG2a
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
T311
Formulation:
Ready-to-use format
Immunogen:
Recombinant tyrosinase protein
Regulatory Status:
IVD
Primary or Secondary:
Primary
Form:
Prediluted
Antigen: Tyrosinase Ab-1
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 12 mL
Research Discipline: Cancer and Tumor Biology
Target Species: __
Isotype: __
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: T311
Formulation: __
Immunogen: Recombinant tyrosinase protein
Regulatory Status: IVD
Primary or Secondary: Primary
Form: Ready-to-Use
Antigen:
Tyrosinase Ab-1
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
12 mL
Research Discipline:
Cancer and Tumor Biology
Target Species:
__
Isotype:
__
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
T311
Formulation:
__
Immunogen:
Recombinant tyrosinase protein
Regulatory Status:
IVD
Primary or Secondary:
Primary
Form:
Ready-to-Use
Antigen: MMP-2 (72kDa Collagenase IV) Ab-2
Classification: Monoclonal
Conjugate: Biotin
Host Species: Mouse
Quantity: 1 mL
Research Discipline: Proteases And Inhibitors
Target Species: Human
Isotype: IgG2a κ
Applications: Immunofluorescence, Immunoprecipitation, Western Blot
Clone: VB3
Formulation: __
Immunogen: Human native 72kDa MMP-2
Regulatory Status: RUO
Primary or Secondary: Primary
Form: Concentrated
Antigen:
MMP-2 (72kDa Collagenase IV) Ab-2
Classification:
Monoclonal
Conjugate:
Biotin
Host Species:
Mouse
Quantity:
1 mL
Research Discipline:
Proteases And Inhibitors
Target Species:
Human
Isotype:
IgG2a κ
Applications:
Immunofluorescence, Immunoprecipitation, Western Blot
Clone:
VB3
Formulation:
__
Immunogen:
Human native 72kDa MMP-2
Regulatory Status:
RUO
Primary or Secondary:
Primary
Form:
Concentrated
Antigen: MMP-2 (72kDa Collagenase IV) Ab-2
Classification: Monoclonal
Conjugate: Biotin
Host Species: Mouse
Quantity: 100 μL
Research Discipline: Proteases And Inhibitors
Target Species: Human
Isotype: IgG2a κ
Applications: Immunofluorescence, Immunoprecipitation, Western Blot
Clone: VB3
Formulation: __
Immunogen: Human native 72kDa MMP-2
Regulatory Status: RUO
Primary or Secondary: Primary
Form: Concentrated
Antigen:
MMP-2 (72kDa Collagenase IV) Ab-2
Classification:
Monoclonal
Conjugate:
Biotin
Host Species:
Mouse
Quantity:
100 μL
Research Discipline:
Proteases And Inhibitors
Target Species:
Human
Isotype:
IgG2a κ
Applications:
Immunofluorescence, Immunoprecipitation, Western Blot
Clone:
VB3
Formulation:
__
Immunogen:
Human native 72kDa MMP-2
Regulatory Status:
RUO
Primary or Secondary:
Primary
Form:
Concentrated