MS891P1ABX

p21 WAF1 Ab-11 Mouse Monoclonal Antibody, Epredia™

Manufacturer: Fischer Scientific

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Antigen

p21superscriptWAF1superscript Ab-11

Classification

Monoclonal

Concentration

1mg/mL

Host Species

Mouse

Quantity

100 μL

Research Discipline

Cell Cycle

Target Species

Human, Rat

Isotype

IgG2b

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

CP74

Conjugate

Unconjugated

Immunogen

Full length human recombinant p21 protein

Regulatory Status

RUO

Primary or Secondary

Primary

Form

Concentrated

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Description

  • Description p21 WAF1 /Cip1/Sdi1/Pic1 is a tumor suppressor protein
  • Expression of p21 WAF1 is induced by wild type, but not mutant, p53 suppressor protein
  • The p21 WAF1 protein binds to cyclin/CDK complexes and inhibits their kinase activity thereby stopping cell cycle progression
  • It also binds to PCNA (proliferating cell nuclear antigen) and blocks DNA replication but not the DNA repair process
  • Host Species: Mouse Clone: CP74 Isotype: IgG2b Species Reactivity: Human and Rat
  • Others not known
  • Epitope: aa 1-80 Immunogen: Full-length human recombinant p21 protein Molecular Weight: 21kDa Positive Control: Raji, PC12 cells Cellular Localization: Nuclear Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Immunoprecipitation (Native verified) Flow Cytometry Note: USA: RUO; Int'l: RUO

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Fischer Scientific

MS891P1ABX

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Antigen:
p21superscriptWAF1superscript Ab-11

Classification:
Monoclonal

Concentration:
1mg/mL

Host Species:
Mouse

Quantity:
100 μL

Research Discipline:
Cell Cycle

Target Species:
Human, Rat

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
CP74

Conjugate:
Unconjugated

Immunogen:
Full length human recombinant p21 protein

Regulatory Status:
RUO

Primary or Secondary:
Primary

Form:
Concentrated

Img

Fischer Scientific

MS891PABX

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Antigen:
p21superscriptWAF1superscript Ab-11

Classification:
Monoclonal

Concentration:
1mg/mL

Host Species:
Mouse

Quantity:
200 μL

Research Discipline:
Cell Cycle

Target Species:
Human, Rat

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
CP74

Conjugate:
Unconjugated

Immunogen:
Full length human recombinant p21 protein

Regulatory Status:
RUO

Primary or Secondary:
Primary

Form:
Concentrated

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Antigen:
Melanoma Marker, Pan Ab-1

Classification:
Monoclonal

Concentration:
__

Host Species:
Mouse

Quantity:
1 mL

Research Discipline:
Cancer and Tumor Biology

Target Species:
Equine

Isotype:
IgG2a κ

Applications:
Immunohistochemistry (Paraffin)

Clone:
HMB45 (gp100, M2-7C10) MART-1 and M2-9E3 (MART-1)

Conjugate:
Unconjugated

Immunogen:
Extract of pigmented melanoma metastases from lymph nodes (HMB45); Recombinant hMART-1 protein (M2-7C10 and M2-9E3)

Regulatory Status:
RUO

Primary or Secondary:
Primary

Form:
Prediluted

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MS939R7

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Antigen:
Melanoma Marker, Pan Ab-1

Classification:
Monoclonal

Concentration:
__

Host Species:
Mouse

Quantity:
7 mL

Research Discipline:
Cancer and Tumor Biology

Target Species:
Equine

Isotype:
IgG2a κ

Applications:
Immunohistochemistry (Paraffin)

Clone:
HMB45 (gp100, M2-7C10) MART-1 and M2-9E3 (MART-1)

Conjugate:
Unconjugated

Immunogen:
Extract of pigmented melanoma metastases from lymph nodes (HMB45); Recombinant hMART-1 protein (M2-7C10 and M2-9E3)

Regulatory Status:
RUO

Primary or Secondary:
Primary

Form:
Prediluted