L-Selectin/CD62L Antibody (FMC46), Alexa Fluor™ 750, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | N106388A70-Each-of-1 | In Stock | ₹ 52,191.60 |
N106388A70 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,191.60
GST (18%): ₹ 9,394.488
Total Price: ₹ 61,586.088
Antigen
L-Selectin/CD62L
Classification
Monoclonal
Conjugate
Alexa Fluor 750
Formulation
50 mM sodium borate with 0.05% sodium azide
Gene Symbols
SELL
Immunogen
PHA stimulated lymphoblasts.
Quantity
0.1 mL
Primary or Secondary
Primary
Test Specificity
NB100-65388 recognizes human CD62L, also known a L-selectin, a 74-95kDa member of the selectin family of adhesion receptors, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin). Human CD62L is constitutively expressed on most leucocytes including monocytes, granulocytes, lymphocytes, NK cells, bone marrow myeloid progenitor cells and on a subset of thymocytes. CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naive lymphocytes to lymph nodes and Peyers patches via HEV. Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, where CD62L is rapidly shed as soluble L-selectin, but surface expression still remains. The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation.
Content And Storage
Store at 4°C in the dark.
Applications
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)
Clone
FMC46
Dilution
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen
Gene Alias
CD62L, CD62L antigen, gp90-MEL, hLHRc, LAM-1, LAM1LECAM1, Leu-8, LEU8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LNHRTQ1, LSEL, L-selectin, Lyam-1, LYAM1CD62 antigen-like family member L, Lymph node homing receptor, lymphocyte adhesion molecule 1, pln homing receptor, PLNHR, selectin L
Host Species
Mouse
Purification Method
Protein G purified
Research Discipline
Adaptive Immunity, B Cell Development and Differentiation Markers, Cardiovascular Biology, Glycobiology, Immunology, Lipid and Metabolism, Myeloid derived Suppressor Cell, Signal Transduction, Stem Cells
Gene ID (Entrez)
6402.0
Target Species
Human, Bovine, Canine, Primate
Isotype
IgG2b
Related Products
Description
- Description L-Selectin/CD62L Monoclonal specifically detects L-Selectin/CD62L in Human, Bovine, Canine, Primate samples
- It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen.
Compare Similar Items
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Antigen: L-Selectin/CD62L
Classification: Monoclonal
Conjugate: Alexa Fluor 750
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: SELL
Immunogen: PHA stimulated lymphoblasts.
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: NB100-65388 recognizes human CD62L, also known a L-selectin, a 74-95kDa member of the selectin family of adhesion receptors, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin). Human CD62L is constitutively expressed on most leucocytes including monocytes, granulocytes, lymphocytes, NK cells, bone marrow myeloid progenitor cells and on a subset of thymocytes. CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naive lymphocytes to lymph nodes and Peyers patches via HEV. Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, where CD62L is rapidly shed as soluble L-selectin, but surface expression still remains. The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation.
Content And Storage: Store at 4°C in the dark.
Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)
Clone: FMC46
Dilution: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen
Gene Alias: CD62L, CD62L antigen, gp90-MEL, hLHRc, LAM-1, LAM1LECAM1, Leu-8, LEU8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LNHRTQ1, LSEL, L-selectin, Lyam-1, LYAM1CD62 antigen-like family member L, Lymph node homing receptor, lymphocyte adhesion molecule 1, pln homing receptor, PLNHR, selectin L
Host Species: Mouse
Purification Method: Protein G purified
Research Discipline: Adaptive Immunity, B Cell Development and Differentiation Markers, Cardiovascular Biology, Glycobiology, Immunology, Lipid and Metabolism, Myeloid derived Suppressor Cell, Signal Transduction, Stem Cells
Gene ID (Entrez): 6402.0
Target Species: Human, Bovine, Canine, Primate
Isotype: IgG2b
Antigen: L-Selectin/CD62L
Classification: Monoclonal
Conjugate: Alexa Fluor 594
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: SELL
Immunogen: PHA stimulated lymphoblasts.
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: NB100-65388 recognizes human CD62L, also known a L-selectin, a 74-95kDa member of the selectin family of adhesion receptors, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin). Human CD62L is constitutively expressed on most leucocytes including monocytes, granulocytes, lymphocytes, NK cells, bone marrow myeloid progenitor cells and on a subset of thymocytes. CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naive lymphocytes to lymph nodes and Peyers patches via HEV. Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, where CD62L is rapidly shed as soluble L-selectin, but surface expression still remains. The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation.
Content And Storage: Store at 4°C in the dark.
Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)
Clone: FMC46
Dilution: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen
Gene Alias: CD62L, CD62L antigen, gp90-MEL, hLHRc, LAM-1, LAM1LECAM1, Leu-8, LEU8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LNHRTQ1, LSEL, L-selectin, Lyam-1, LYAM1CD62 antigen-like family member L, Lymph node homing receptor, lymphocyte adhesion molecule 1, pln homing receptor, PLNHR, selectin L
Host Species: Mouse
Purification Method: Protein G purified
Research Discipline: Adaptive Immunity, B Cell Development and Differentiation Markers, Cardiovascular Biology, Glycobiology, Immunology, Lipid and Metabolism, Myeloid derived Suppressor Cell, Signal Transduction, Stem Cells
Gene ID (Entrez): 6402.0
Target Species: Human, Bovine, Canine, Primate
Isotype: IgG2b
Antigen: P-Selectin/CD62P
Classification: Monoclonal
Conjugate: Alexa Fluor 532
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: SELP
Immunogen: P-Selectin transfected 300.19 cells.
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: NB100-65391 recognizes the P-Selectin cell surface antigen, a 140kD glycoprotein. P-Selectin is expressed by activated platelets and endothelial cells, and plays an important role in adhesive processes between leucocytes and endothelial cells. Clone Psel.KO.2.12 is reported to inhibit P-selectin-dependent adhesion between HL60 cells and P-selectin transfected COS cells.
Content And Storage: Store at 4°C in the dark.
Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)
Clone: Psel.KO.2.12
Dilution: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen
Gene Alias: CD62P antigen, FLJ45155, PADGEMantigen CD62), selectin P (granule membrane protein 140kDa, antigen CD62)
Host Species: Mouse
Purification Method: Protein G purified
Research Discipline: __
Gene ID (Entrez): 6403.0
Target Species: Human, Rat, Goat, Sheep
Isotype: IgG1