N10696A94

ROCK1 Antibody (154C1465), Alexa Fluor™ 594 - (active/cleaved), Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 N10696A94-Each-of-1 In Stock ₹ 53,218.32

N10696A94 - Each of 1

₹ 53,218.32

In Stock

Quantity

1

Base Price: ₹ 53,218.32

GST (18%): ₹ 9,579.298

Total Price: ₹ 62,797.618

Antigen

ROCK1

Classification

Monoclonal

Conjugate

Alexa Fluor 594

Formulation

50 mM sodium borate with 0.05% sodium azide

Gene Symbols

ROCK1

Immunogen

This antibody was generated by immunizing mice with a synthetic peptide sequence corresponding to amino acids 1114-1126 GNLPESRIEGWLS of human ROCK-1. This sequence is 100% conserved between human, chimpanzee, mouse, rat, dog, and rabbit. This immunogen peptide sequence is adjacent to the caspase-3 cleavage site of ROCK-1.

Primary or Secondary

Primary

Test Specificity

This mAb recognizes the cleaved C-terminus of ROCK-1. It does not recognize the full-length protein. Since ROCK-1 is cleaved by caspase-3 during apoptosis, this may be used for detection of apoptosis.

Content And Storage

Store at 4°C in the dark.

Applications

Western Blot, Immunocytochemistry, Immunofluorescence

Clone

154C1465

Dilution

Western Blot, Immunocytochemistry/Immunofluorescence

Gene Alias

EC 2.7.11, EC 2.7.11.1, MGC131603, MGC43611, p160 ROCK-1, p160ROCK, p160-ROCK, PRO0435, Renal carcinoma antigen NY-REN-35, Rho kinase, rho-associated protein kinase 1, Rho-associated, coiled-coil containing protein kinase 1, Rho-associated, coiled-coil-containing protein kinase 1

Host Species

Mouse

Quantity

0.1 mL

Gene ID (Entrez)

6093

Target Species

Human, Mouse, Rat, Canine, Primate, Rabbit

Isotype

IgG

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Description

  • ROCK1 Monoclonal specifically detects ROCK1 in Human, Mouse, Rat, Canine, Primate, Rabbit samples
  • It is validated for Western Blot, Immunocytochemistry/Immunofluorescence.

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Img

Novus Biologicals

N10696A94

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Antigen:
ROCK1

Classification:
Monoclonal

Conjugate:
Alexa Fluor 594

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
ROCK1

Immunogen:
This antibody was generated by immunizing mice with a synthetic peptide sequence corresponding to amino acids 1114-1126 GNLPESRIEGWLS of human ROCK-1. This sequence is 100% conserved between human, chimpanzee, mouse, rat, dog, and rabbit. This immunogen peptide sequence is adjacent to the caspase-3 cleavage site of ROCK-1.

Primary or Secondary:
Primary

Test Specificity:
This mAb recognizes the cleaved C-terminus of ROCK-1. It does not recognize the full-length protein. Since ROCK-1 is cleaved by caspase-3 during apoptosis, this may be used for detection of apoptosis.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Immunocytochemistry, Immunofluorescence

Clone:
154C1465

Dilution:
Western Blot, Immunocytochemistry/Immunofluorescence

Gene Alias:
EC 2.7.11, EC 2.7.11.1, MGC131603, MGC43611, p160 ROCK-1, p160ROCK, p160-ROCK, PRO0435, Renal carcinoma antigen NY-REN-35, Rho kinase, rho-associated protein kinase 1, Rho-associated, coiled-coil containing protein kinase 1, Rho-associated, coiled-coil-containing protein kinase 1

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
6093

Target Species:
Human, Mouse, Rat, Canine, Primate, Rabbit

Isotype:
IgG

Img

Novus Biologicals

N10698A94

--


Antigen:
RB1

Classification:
Monoclonal

Conjugate:
Alexa Fluor 594

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
RB1

Immunogen:
A synthetic peptide corresponding to a region of the caspase-3-induced cleavage site of human Rb was used as immunogen.

Primary or Secondary:
Primary

Test Specificity:
The antibody recognizes cleaved Rb (DRb-p70). The antibody does not recognize full-length Rb. In camptothecin treated HL60, an ∼68 kDa band is observed. DRb-p70 exists in vivo as an N-terminally truncated form of Rb (Liu et al.). DRb-p70 is thought to be the product of alternative translation and is expressed in primary myeloid cells in fetal liver, bone marrow and spleen. DRb-p70 is also specifically expressed in tumor-associated macrophages (TAMs). TAMs are an important targets of cancer therapy. DRb-p70 is a marker of TAMs, and maybe useful for identifying tumors with macrophage infiltration (Liu et al, 2005).

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen), KnockDown

Clone:
172C1094

Dilution:
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Knockdown Validated

Gene Alias:
OSRC, osteosarcoma, p105-Rb, pp110, pRb, Rb, retinoblastoma 1, retinoblastoma suspectibility protein, retinoblastoma-associated protein

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
5925

Target Species:
Human, Mouse

Isotype:
IgG1

Img

Novus Biologicals

N10699A30

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Antigen:
Integrin beta 4/CD104

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
ITGB4

Immunogen:
Purified alpha6 beta4 integrin from A431 cells

Primary or Secondary:
Primary

Test Specificity:
NB100-65599 recognizes the human beta4 integrin (also known as CD104), a 205kD glycoprotein which associates with the alpha6 integrin to form the alpha6/beta4 complex. CD104 is expressed on epithelial cells, Schwann cells and various tumour cell lines. NB100-65599 recognizes an extracellular epitope on the CD104 molecule.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

Clone:
450-9D

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

Gene Alias:
CD104, CD104 antigen, GP150, integrin beta-4, integrin beta-4 subunit, integrin, beta 4

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
3691

Target Species:
Human, Ferret, Mustelid

Isotype:
IgG1

Img

Novus Biologicals

N10699A32

--


Antigen:
Integrin beta 4/CD104

Classification:
Monoclonal

Conjugate:
Alexa Fluor 532

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
ITGB4

Immunogen:
Purified alpha6 beta4 integrin from A431 cells

Primary or Secondary:
Primary

Test Specificity:
NB100-65599 recognizes the human beta4 integrin (also known as CD104), a 205kD glycoprotein which associates with the alpha6 integrin to form the alpha6/beta4 complex. CD104 is expressed on epithelial cells, Schwann cells and various tumour cell lines. NB100-65599 recognizes an extracellular epitope on the CD104 molecule.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

Clone:
450-9D

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

Gene Alias:
CD104, CD104 antigen, GP150, integrin beta-4, integrin beta-4 subunit, integrin, beta 4

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
3691.0

Target Species:
Human, Ferret, Mustelid

Isotype:
IgG1