N140894APC7
P2X7/P2RX7 Antibody (Hano43), Allophycocyanin/Cy7, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | N140894APC7-Each-of-1 | In Stock | ₹ 58,351.92 |
N140894APC7 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 58,351.92
GST (18%): ₹ 10,503.346
Total Price: ₹ 68,855.266
Antigen
P2X7/P2RX7
Classification
Monoclonal
Conjugate
APC-Cyanine7
Formulation
PBS with 0.05% Sodium Azide
Gene Symbols
P2RX7
Immunogen
A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Quantity
0.1 mL
Gene ID (Entrez)
5027.0
Target Species
Mouse
Isotype
IgG2b
Applications
Flow Cytometry
Clone
Hano43
Dilution
Flow Cytometry
Gene Alias
ATP receptor, MGC20089, P2X purinoceptor 7, P2X7P2X7 receptor, P2X7R, P2Z receptor, Purinergic receptor, purinergic receptor P2X, ligand-gated ion channel, 7, purinergic receptor P2X7 variant A
Host Species
Rat
Purification Method
Protein G purified
Primary or Secondary
Primary
Test Specificity
This antibody recognises the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturation and release of IL-1 and other IL-1 family members during inflammation. As such, P2X7 blockers might be useful as anti-inflammatory agents.
Content And Storage
Store at 4°C in the dark. Do not freeze.
Related Products
Description
- Description P2X7/P2RX7 Monoclonal specifically detects P2X7/P2RX7 in Mouse samples
- It is validated for Flow Cytometry.
Compare Similar Items
Show Difference
Antigen: P2X7/P2RX7
Classification: Monoclonal
Conjugate: APC-Cyanine7
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: P2RX7
Immunogen: A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Quantity: 0.1 mL
Gene ID (Entrez): 5027.0
Target Species: Mouse
Isotype: IgG2b
Applications: Flow Cytometry
Clone: Hano43
Dilution: Flow Cytometry
Gene Alias: ATP receptor, MGC20089, P2X purinoceptor 7, P2X7P2X7 receptor, P2X7R, P2Z receptor, Purinergic receptor, purinergic receptor P2X, ligand-gated ion channel, 7, purinergic receptor P2X7 variant A
Host Species: Rat
Purification Method: Protein G purified
Primary or Secondary: Primary
Test Specificity: This antibody recognises the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturation and release of IL-1 and other IL-1 family members during inflammation. As such, P2X7 blockers might be useful as anti-inflammatory agents.
Content And Storage: Store at 4°C in the dark. Do not freeze.
Antigen:
P2X7/P2RX7
Classification:
Monoclonal
Conjugate:
APC-Cyanine7
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
P2RX7
Immunogen:
A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Quantity:
0.1 mL
Gene ID (Entrez):
5027.0
Target Species:
Mouse
Isotype:
IgG2b
Applications:
Flow Cytometry
Clone:
Hano43
Dilution:
Flow Cytometry
Gene Alias:
ATP receptor, MGC20089, P2X purinoceptor 7, P2X7P2X7 receptor, P2X7R, P2Z receptor, Purinergic receptor, purinergic receptor P2X, ligand-gated ion channel, 7, purinergic receptor P2X7 variant A
Host Species:
Rat
Purification Method:
Protein G purified
Primary or Secondary:
Primary
Test Specificity:
This antibody recognises the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturation and release of IL-1 and other IL-1 family members during inflammation. As such, P2X7 blockers might be useful as anti-inflammatory agents.
Content And Storage:
Store at 4°C in the dark. Do not freeze.
Antigen: P2X7/P2RX7
Classification: Monoclonal
Conjugate: PE-Cyanine5.5
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: P2RX7
Immunogen: A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Quantity: 0.1 mL
Gene ID (Entrez): 5027.0
Target Species: Mouse
Isotype: IgG2b
Applications: Flow Cytometry
Clone: Hano43
Dilution: Flow Cytometry
Gene Alias: ATP receptor, MGC20089, P2X purinoceptor 7, P2X7P2X7 receptor, P2X7R, P2Z receptor, Purinergic receptor, purinergic receptor P2X, ligand-gated ion channel, 7, purinergic receptor P2X7 variant A
Host Species: Rat
Purification Method: Protein G purified
Primary or Secondary: Primary
Test Specificity: This antibody recognises the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturation and release of IL-1 and other IL-1 family members during inflammation. As such, P2X7 blockers might be useful as anti-inflammatory agents.
Content And Storage: Store at 4°C in the dark. Do not freeze.
Antigen:
P2X7/P2RX7
Classification:
Monoclonal
Conjugate:
PE-Cyanine5.5
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
P2RX7
Immunogen:
A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Quantity:
0.1 mL
Gene ID (Entrez):
5027.0
Target Species:
Mouse
Isotype:
IgG2b
Applications:
Flow Cytometry
Clone:
Hano43
Dilution:
Flow Cytometry
Gene Alias:
ATP receptor, MGC20089, P2X purinoceptor 7, P2X7P2X7 receptor, P2X7R, P2Z receptor, Purinergic receptor, purinergic receptor P2X, ligand-gated ion channel, 7, purinergic receptor P2X7 variant A
Host Species:
Rat
Purification Method:
Protein G purified
Primary or Secondary:
Primary
Test Specificity:
This antibody recognises the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturation and release of IL-1 and other IL-1 family members during inflammation. As such, P2X7 blockers might be useful as anti-inflammatory agents.
Content And Storage:
Store at 4°C in the dark. Do not freeze.
Antigen: Cytochrome b245 alpha
Classification: Monoclonal
Conjugate: APC-Cyanine7
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: CYBA
Immunogen: Cytochrome B245 solubilised in octyl-beta-gluycopyranoside
Quantity: 0.1 mL
Gene ID (Entrez): 1535.0
Target Species: Human
Isotype: IgG1
Applications: Flow Cytometry
Clone: CS9
Dilution: Flow Cytometry
Gene Alias: cytochrome b light chain, Cytochrome b(558) alpha chain, cytochrome b(558) alpha-subunit, cytochrome b, alpha polypeptide, cytochrome b-245 light chain, cytochrome b-245, alpha polypeptide, Cytochrome b558 subunit alpha, flavocytochrome b-558 alpha polypeptide, Neutrophil cytochrome b 22 kDa polypeptide, p22 phagocyte B-cytochrome, p22phox, p22-phox, Superoxide-generating NADPH oxidase light chain subunit
Host Species: Mouse
Purification Method: Protein G purified
Primary or Secondary: Primary
Test Specificity: This antibody recognizes the light chain of cytochrome B245, also known as p22phox, a subunit of the nicotinamide adenine dinucleotide phosphate-oxidase (NADPH oxidase). NADPH oxidase is a membrane-bound enzyme complex in neutrophils that produces the superoxide anion (O2-) by transferring single electrons from NADPH inside the cell across the membrane and coupling them to molecular oxygen. Superoxide is used for the destruction of pathogens. Individuals with defects in NADPH oxidase suffer from chronic granulomatous disease, characterized by severe recurrent infections.
Content And Storage: Store at 4°C in the dark. Do not freeze.
Antigen:
Cytochrome b245 alpha
Classification:
Monoclonal
Conjugate:
APC-Cyanine7
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
CYBA
Immunogen:
Cytochrome B245 solubilised in octyl-beta-gluycopyranoside
Quantity:
0.1 mL
Gene ID (Entrez):
1535.0
Target Species:
Human
Isotype:
IgG1
Applications:
Flow Cytometry
Clone:
CS9
Dilution:
Flow Cytometry
Gene Alias:
cytochrome b light chain, Cytochrome b(558) alpha chain, cytochrome b(558) alpha-subunit, cytochrome b, alpha polypeptide, cytochrome b-245 light chain, cytochrome b-245, alpha polypeptide, Cytochrome b558 subunit alpha, flavocytochrome b-558 alpha polypeptide, Neutrophil cytochrome b 22 kDa polypeptide, p22 phagocyte B-cytochrome, p22phox, p22-phox, Superoxide-generating NADPH oxidase light chain subunit
Host Species:
Mouse
Purification Method:
Protein G purified
Primary or Secondary:
Primary
Test Specificity:
This antibody recognizes the light chain of cytochrome B245, also known as p22phox, a subunit of the nicotinamide adenine dinucleotide phosphate-oxidase (NADPH oxidase). NADPH oxidase is a membrane-bound enzyme complex in neutrophils that produces the superoxide anion (O2-) by transferring single electrons from NADPH inside the cell across the membrane and coupling them to molecular oxygen. Superoxide is used for the destruction of pathogens. Individuals with defects in NADPH oxidase suffer from chronic granulomatous disease, characterized by severe recurrent infections.
Content And Storage:
Store at 4°C in the dark. Do not freeze.
Antigen: Cytochrome b245 alpha
Classification: Monoclonal
Conjugate: PE-Cyanine5.5
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: CYBA
Immunogen: Cytochrome B245 solubilised in octyl-beta-gluycopyranoside
Quantity: 0.1 mL
Gene ID (Entrez): 1535.0
Target Species: Human
Isotype: IgG1
Applications: Flow Cytometry
Clone: CS9
Dilution: Flow Cytometry
Gene Alias: cytochrome b light chain, Cytochrome b(558) alpha chain, cytochrome b(558) alpha-subunit, cytochrome b, alpha polypeptide, cytochrome b-245 light chain, cytochrome b-245, alpha polypeptide, Cytochrome b558 subunit alpha, flavocytochrome b-558 alpha polypeptide, Neutrophil cytochrome b 22 kDa polypeptide, p22 phagocyte B-cytochrome, p22phox, p22-phox, Superoxide-generating NADPH oxidase light chain subunit
Host Species: Mouse
Purification Method: Protein G purified
Primary or Secondary: Primary
Test Specificity: This antibody recognizes the light chain of cytochrome B245, also known as p22phox, a subunit of the nicotinamide adenine dinucleotide phosphate-oxidase (NADPH oxidase). NADPH oxidase is a membrane-bound enzyme complex in neutrophils that produces the superoxide anion (O2-) by transferring single electrons from NADPH inside the cell across the membrane and coupling them to molecular oxygen. Superoxide is used for the destruction of pathogens. Individuals with defects in NADPH oxidase suffer from chronic granulomatous disease, characterized by severe recurrent infections.
Content And Storage: Store at 4°C in the dark. Do not freeze.
Antigen:
Cytochrome b245 alpha
Classification:
Monoclonal
Conjugate:
PE-Cyanine5.5
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
CYBA
Immunogen:
Cytochrome B245 solubilised in octyl-beta-gluycopyranoside
Quantity:
0.1 mL
Gene ID (Entrez):
1535.0
Target Species:
Human
Isotype:
IgG1
Applications:
Flow Cytometry
Clone:
CS9
Dilution:
Flow Cytometry
Gene Alias:
cytochrome b light chain, Cytochrome b(558) alpha chain, cytochrome b(558) alpha-subunit, cytochrome b, alpha polypeptide, cytochrome b-245 light chain, cytochrome b-245, alpha polypeptide, Cytochrome b558 subunit alpha, flavocytochrome b-558 alpha polypeptide, Neutrophil cytochrome b 22 kDa polypeptide, p22 phagocyte B-cytochrome, p22phox, p22-phox, Superoxide-generating NADPH oxidase light chain subunit
Host Species:
Mouse
Purification Method:
Protein G purified
Primary or Secondary:
Primary
Test Specificity:
This antibody recognizes the light chain of cytochrome B245, also known as p22phox, a subunit of the nicotinamide adenine dinucleotide phosphate-oxidase (NADPH oxidase). NADPH oxidase is a membrane-bound enzyme complex in neutrophils that produces the superoxide anion (O2-) by transferring single electrons from NADPH inside the cell across the membrane and coupling them to molecular oxygen. Superoxide is used for the destruction of pathogens. Individuals with defects in NADPH oxidase suffer from chronic granulomatous disease, characterized by severe recurrent infections.
Content And Storage:
Store at 4°C in the dark. Do not freeze.