N233076PEC7

CD34 Antibody (ICO-115), PE/Cy7, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 N233076PEC7-Each-of-1 In Stock ₹ 61,517.64

N233076PEC7 - Each of 1

₹ 61,517.64

In Stock

Quantity

1

Base Price: ₹ 61,517.64

GST (18%): ₹ 11,073.175

Total Price: ₹ 72,590.815

Antigen

CD34

Classification

Monoclonal

Conjugate

PE-Cyanine7

Formulation

PBS with 0.05% Sodium Azide

Gene Symbols

CD34

Immunogen

Blast cells from a chronic myeloid leukemia patient were used as the immunogen for the CD34 antibody.

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

This antibody recognizes a carbohydrate epitope on a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34 (VI international workshop on human differentiation antigens). Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but shows low specificity.

Content And Storage

Store at 4°C in the dark. Do not freeze.

Applications

Flow Cytometry

Clone

ICO-115

Dilution

Flow Cytometry

Gene Alias

CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule

Host Species

Mouse

Purification Method

Protein G purified

Research Discipline

Adaptive Immunity, Angiogenesis, B Cell Development and Differentiation Markers, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Hypoxia, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Tumor Suppressors

Gene ID (Entrez)

947.0

Target Species

Human, Rat

Isotype

IgG1 κ

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Description

  • CD34 Monoclonal specifically detects CD34 in Human, Rat samples
  • It is validated for Flow Cytometry.

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Img

Novus Biologicals

N233076PEC7

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Antigen:
CD34

Classification:
Monoclonal

Conjugate:
PE-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
CD34

Immunogen:
Blast cells from a chronic myeloid leukemia patient were used as the immunogen for the CD34 antibody.

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes a carbohydrate epitope on a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34 (VI international workshop on human differentiation antigens). Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but shows low specificity.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
ICO-115

Dilution:
Flow Cytometry

Gene Alias:
CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule

Host Species:
Mouse

Purification Method:
Protein G purified

Research Discipline:
Adaptive Immunity, Angiogenesis, B Cell Development and Differentiation Markers, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Hypoxia, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Tumor Suppressors

Gene ID (Entrez):
947.0

Target Species:
Human, Rat

Isotype:
IgG1 κ

Img

Novus Biologicals

N233078APC7

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Antigen:
EpCAM/TROP1

Classification:
Monoclonal

Conjugate:
APC-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
EPCAM

Immunogen:
Small cell lung carcinoma cells

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
VU-1D9

Dilution:
Flow Cytometry

Gene Alias:
17-1A, 323/A3, ACSTD1, antigen identified by monoclonal AUA1, CD326 antigen, Cell surface glycoprotein Trop-1, chromosome 4, surface marker (35kD glycoprotein), DIAR5, EGP, EGP-2, EGP314, EGP40, EpCAM, epithelial cell adhesion molecule, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, ESA, GA733-2EGP34, hEGP314, HNPCC8, KS 1/4 antigen, KS1/4, KSAHEA125, M1S2, M4S1Ly74, Major gastrointestinal tumor-associated protein GA733-2, MIC18MH99, MOC31, TACST-1, TACSTD1, TROP1CD326, Tumor-associated calcium signal transducer 1CO-17A

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Cancer, Cancer Stem Cells, Tumor Biomarkers

Gene ID (Entrez):
4072.0

Target Species:
Human, Ferret (Negative), Rat (Negative)

Isotype:
IgG1 κ

Img

Novus Biologicals

N233078PEC7

--


Antigen:
EpCAM/TROP1

Classification:
Monoclonal

Conjugate:
PE-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
EPCAM

Immunogen:
Small cell lung carcinoma cells

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
VU-1D9

Dilution:
Flow Cytometry

Gene Alias:
17-1A, 323/A3, ACSTD1, antigen identified by monoclonal AUA1, CD326 antigen, Cell surface glycoprotein Trop-1, chromosome 4, surface marker (35kD glycoprotein), DIAR5, EGP, EGP-2, EGP314, EGP40, EpCAM, epithelial cell adhesion molecule, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, ESA, GA733-2EGP34, hEGP314, HNPCC8, KS 1/4 antigen, KS1/4, KSAHEA125, M1S2, M4S1Ly74, Major gastrointestinal tumor-associated protein GA733-2, MIC18MH99, MOC31, TACST-1, TACSTD1, TROP1CD326, Tumor-associated calcium signal transducer 1CO-17A

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Cancer, Cancer Stem Cells, Tumor Biomarkers

Gene ID (Entrez):
4072.0

Target Species:
Human, Ferret (Negative), Rat (Negative)

Isotype:
IgG1 κ

Img

Novus Biologicals

N23308APCY7

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Antigen:
CD74

Classification:
Monoclonal

Conjugate:
APC-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
CD74

Immunogen:
SU-DHL-4 lymphoma cells were used as the immunogen for the CD74 antibody

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
It recognizes a protein of ∼35kDa, identified as CD74 (Workshop IV). CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma (+).

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
LN-2

Dilution:
Flow Cytometry

Gene Alias:
CD74 antigen, CD74 antigen (invariant polypeptide of major histocompatibility complex, classII antigen-associated), CD74 molecule, major histocompatibility complex, class II invariant chain, DHLAGgamma chain of class II antigens, HLA class II histocompatibility antigen gamma chain, HLADG, HLA-DR antigens-associated invariant chain, HLA-DR-gamma, Ia antigen-associated invariant chain, Ia-associated invariant chain, Ia-GAMMA, Ii, MHC HLA-DR gamma chain, p33

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Immunology

Gene ID (Entrez):
972.0

Target Species:
Human, Mouse, Baboon, Rat (Negative)

Isotype:
IgG1 κ