N234401J549
GFAP Antibody (SPM248), Janelia Fluor™ 549, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | N234401J549-Each-of-1 | In Stock | ₹ 56,298.48 |
N234401J549 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 56,298.48
GST (18%): ₹ 10,133.726
Total Price: ₹ 66,432.206
Antigen
GFAP
Classification
Monoclonal
Conjugate
Janelia Fluor 549
Formulation
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols
GFAP
Immunogen
GFAP isolated from pig spinal cord (Uniprot: P14136)
Purification Method
Protein A or G purified
Research Discipline
Astrocyte Markers, Cancer, Cell Biology, Cellular Markers, Chaperone Mediated Autophagy (CMA), Inflammation, Neurodegeneration, Neuroscience, Signal Transduction, Stem Cell Markers
Gene ID (Entrez)
2670.0
Target Species
Human, Mouse, Rat, Porcine, Bovine, Chicken, Rabbit
Isotype
IgG1 κ
Applications
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone
SPM248
Dilution
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias
FLJ45472, GFAP astrocytes, glial fibrillary acidic protein
Host Species
Mouse
Molecular Weight of Antigen
50 kDa
Quantity
0.1 mL
Primary or Secondary
Primary
Test Specificity
This monoclonal antibody recognizes a protein of ∼50kDa which is identified as Glial Fibrillary Acidic Protein (GFAP). It shows no cross-reaction with other intermediate filament proteins. GFAP is specifically found in astroglia. GFAP is a very popular marker for localizing benign astrocyte and neoplastic cells of glial origin in the central nervous system. Antibody to GFAP is useful in differentiating primary gliomas from metastatic lesions in the brain and for documenting astrocytic differentiation in tumors outside the CNS.
Content And Storage
Store at 4°C in the dark.
Related Products
Description
- GFAP Monoclonal specifically detects GFAP in Human, Mouse, Rat, Porcine, Bovine, Chicken, Rabbit samples
- It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
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Antigen: GFAP
Classification: Monoclonal
Conjugate: Janelia Fluor 549
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: GFAP
Immunogen: GFAP isolated from pig spinal cord (Uniprot: P14136)
Purification Method: Protein A or G purified
Research Discipline: Astrocyte Markers, Cancer, Cell Biology, Cellular Markers, Chaperone Mediated Autophagy (CMA), Inflammation, Neurodegeneration, Neuroscience, Signal Transduction, Stem Cell Markers
Gene ID (Entrez): 2670.0
Target Species: Human, Mouse, Rat, Porcine, Bovine, Chicken, Rabbit
Isotype: IgG1 κ
Applications: Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: SPM248
Dilution: Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias: FLJ45472, GFAP astrocytes, glial fibrillary acidic protein
Host Species: Mouse
Molecular Weight of Antigen: 50 kDa
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody recognizes a protein of ∼50kDa which is identified as Glial Fibrillary Acidic Protein (GFAP). It shows no cross-reaction with other intermediate filament proteins. GFAP is specifically found in astroglia. GFAP is a very popular marker for localizing benign astrocyte and neoplastic cells of glial origin in the central nervous system. Antibody to GFAP is useful in differentiating primary gliomas from metastatic lesions in the brain and for documenting astrocytic differentiation in tumors outside the CNS.
Content And Storage: Store at 4°C in the dark.
Antigen:
GFAP
Classification:
Monoclonal
Conjugate:
Janelia Fluor 549
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
GFAP
Immunogen:
GFAP isolated from pig spinal cord (Uniprot: P14136)
Purification Method:
Protein A or G purified
Research Discipline:
Astrocyte Markers, Cancer, Cell Biology, Cellular Markers, Chaperone Mediated Autophagy (CMA), Inflammation, Neurodegeneration, Neuroscience, Signal Transduction, Stem Cell Markers
Gene ID (Entrez):
2670.0
Target Species:
Human, Mouse, Rat, Porcine, Bovine, Chicken, Rabbit
Isotype:
IgG1 κ
Applications:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
SPM248
Dilution:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias:
FLJ45472, GFAP astrocytes, glial fibrillary acidic protein
Host Species:
Mouse
Molecular Weight of Antigen:
50 kDa
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody recognizes a protein of ∼50kDa which is identified as Glial Fibrillary Acidic Protein (GFAP). It shows no cross-reaction with other intermediate filament proteins. GFAP is specifically found in astroglia. GFAP is a very popular marker for localizing benign astrocyte and neoplastic cells of glial origin in the central nervous system. Antibody to GFAP is useful in differentiating primary gliomas from metastatic lesions in the brain and for documenting astrocytic differentiation in tumors outside the CNS.
Content And Storage:
Store at 4°C in the dark.
Antigen: FoxP3
Classification: Monoclonal
Conjugate: Janelia Fluor 549
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: FOXP3
Immunogen: Full-length human FoxP3 protein (Uniprot: Q9ZS1)
Purification Method: Protein A or G purified
Research Discipline: Adaptive Immunity, Cell Biology, Chromatin Research, Immunology, Regulatory Immunology, Transcription Factors and Regulators
Gene ID (Entrez): 50943.0
Target Species: Human, Mouse, Primate
Isotype: IgG1 κ
Applications: Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Clone: SPM579
Dilution: Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
Gene Alias: AIID, AIIDMGC141961, DIETER, forkhead box P3, Forkhead Box Protein P3, FOXP3delta7, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked, IPEX, JM2, MGC141961, MGC141963, PIDX, PIDXMGC141963, Scurfin, XPID, XPIDpolyendocrinopathy, enteropathy, X-linked
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 47-55kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.
Content And Storage: Store at 4°C in the dark.
Antigen:
FoxP3
Classification:
Monoclonal
Conjugate:
Janelia Fluor 549
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
FOXP3
Immunogen:
Full-length human FoxP3 protein (Uniprot: Q9ZS1)
Purification Method:
Protein A or G purified
Research Discipline:
Adaptive Immunity, Cell Biology, Chromatin Research, Immunology, Regulatory Immunology, Transcription Factors and Regulators
Gene ID (Entrez):
50943.0
Target Species:
Human, Mouse, Primate
Isotype:
IgG1 κ
Applications:
Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Clone:
SPM579
Dilution:
Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
Gene Alias:
AIID, AIIDMGC141961, DIETER, forkhead box P3, Forkhead Box Protein P3, FOXP3delta7, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked, IPEX, JM2, MGC141961, MGC141963, PIDX, PIDXMGC141963, Scurfin, XPID, XPIDpolyendocrinopathy, enteropathy, X-linked
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 47-55kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.
Content And Storage:
Store at 4°C in the dark.
Antigen: FoxP3
Classification: Monoclonal
Conjugate: Janelia Fluor 646
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: FOXP3
Immunogen: Full-length human FoxP3 protein (Uniprot: Q9ZS1)
Purification Method: Protein A or G purified
Research Discipline: Adaptive Immunity, Cell Biology, Chromatin Research, Immunology, Regulatory Immunology, Transcription Factors and Regulators
Gene ID (Entrez): 50943.0
Target Species: Human, Mouse, Primate
Isotype: IgG1 κ
Applications: Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Clone: SPM579
Dilution: Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
Gene Alias: AIID, AIIDMGC141961, DIETER, forkhead box P3, Forkhead Box Protein P3, FOXP3delta7, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked, IPEX, JM2, MGC141961, MGC141963, PIDX, PIDXMGC141963, Scurfin, XPID, XPIDpolyendocrinopathy, enteropathy, X-linked
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 47-55kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.
Content And Storage: Store at 4°C in the dark.
Antigen:
FoxP3
Classification:
Monoclonal
Conjugate:
Janelia Fluor 646
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
FOXP3
Immunogen:
Full-length human FoxP3 protein (Uniprot: Q9ZS1)
Purification Method:
Protein A or G purified
Research Discipline:
Adaptive Immunity, Cell Biology, Chromatin Research, Immunology, Regulatory Immunology, Transcription Factors and Regulators
Gene ID (Entrez):
50943.0
Target Species:
Human, Mouse, Primate
Isotype:
IgG1 κ
Applications:
Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Clone:
SPM579
Dilution:
Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
Gene Alias:
AIID, AIIDMGC141961, DIETER, forkhead box P3, Forkhead Box Protein P3, FOXP3delta7, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked, IPEX, JM2, MGC141961, MGC141963, PIDX, PIDXMGC141963, Scurfin, XPID, XPIDpolyendocrinopathy, enteropathy, X-linked
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 47-55kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.
Content And Storage:
Store at 4°C in the dark.
Antigen: Thymidylate Synthase
Classification: Monoclonal
Conjugate: Janelia Fluor 549
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: TYMS
Immunogen: Recombinant full-length human Thymidylate Synthase protein. (Uniprot: P04818 )
Purification Method: Protein A or G purified
Research Discipline: Cancer, Cell Cycle and Replication, DNA Repair, DNA replication Transcription Translation and Splicing, Transcription Factors and Regulators, Translation Control
Gene ID (Entrez): 7298.0
Target Species: Human
Isotype: IgG1 κ
Applications: Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: SPM453
Dilution: Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias: EC 2.1.1.45, HsT422, MGC88736, thymidylate synthase, thymidylate synthetase, TMSTsase, TSase, TSHST422
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: It recognizes a protein of 36kDa, identified as Thymidylate Synthase (TS) (EC 2.1.1.45). TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.
Content And Storage: Store at 4°C in the dark.
Antigen:
Thymidylate Synthase
Classification:
Monoclonal
Conjugate:
Janelia Fluor 549
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
TYMS
Immunogen:
Recombinant full-length human Thymidylate Synthase protein. (Uniprot: P04818 )
Purification Method:
Protein A or G purified
Research Discipline:
Cancer, Cell Cycle and Replication, DNA Repair, DNA replication Transcription Translation and Splicing, Transcription Factors and Regulators, Translation Control
Gene ID (Entrez):
7298.0
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
SPM453
Dilution:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias:
EC 2.1.1.45, HsT422, MGC88736, thymidylate synthase, thymidylate synthetase, TMSTsase, TSase, TSHST422
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
It recognizes a protein of 36kDa, identified as Thymidylate Synthase (TS) (EC 2.1.1.45). TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.
Content And Storage:
Store at 4°C in the dark.