N234511P594
Siglec-3/CD33 Antibody (WM53), PE/Atto594, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | N234511P594-Each-of-1 | In Stock | ₹ 60,448.14 |
N234511P594 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 60,448.14
GST (18%): ₹ 10,880.665
Total Price: ₹ 71,328.805
Antigen
Siglec-3/CD33
Classification
Monoclonal
Conjugate
PE/ATTO 594
Formulation
PBS with 0.05% Sodium Azide
Gene Symbols
CD33
Immunogen
Human AML cells
Quantity
0.1 mL
Primary or Secondary
Primary
Test Specificity
Recognizes a 67kDa glycoprotein, which is identified as CD33 (HLDA IV; WS Code M-505). CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immuno-receptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.
Content And Storage
Store at 4°C in the dark. Do not freeze.
Applications
Flow Cytometry
Clone
WM53
Dilution
Flow Cytometry
Gene Alias
CD33 antigen, CD33 antigen (gp67), CD33 molecule, FLJ00391, myeloid cell surface antigen CD33, p67, sialic acid binding Ig-like lectin 3, Sialic acid-binding Ig-like lectin 3, SIGLEC-3, SIGLEC3gp67
Host Species
Mouse
Purification Method
Protein A or G purified
Research Discipline
Immunology
Gene ID (Entrez)
945.0
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- Siglec-3/CD33 Monoclonal specifically detects Siglec-3/CD33 in Human samples
- It is validated for Flow Cytometry.
Compare Similar Items
Show Difference
Antigen: Siglec-3/CD33
Classification: Monoclonal
Conjugate: PE/ATTO 594
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: CD33
Immunogen: Human AML cells
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Recognizes a 67kDa glycoprotein, which is identified as CD33 (HLDA IV; WS Code M-505). CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immuno-receptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.
Content And Storage: Store at 4°C in the dark. Do not freeze.
Applications: Flow Cytometry
Clone: WM53
Dilution: Flow Cytometry
Gene Alias: CD33 antigen, CD33 antigen (gp67), CD33 molecule, FLJ00391, myeloid cell surface antigen CD33, p67, sialic acid binding Ig-like lectin 3, Sialic acid-binding Ig-like lectin 3, SIGLEC-3, SIGLEC3gp67
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Immunology
Gene ID (Entrez): 945.0
Target Species: Human
Isotype: IgG1 κ
Antigen:
Siglec-3/CD33
Classification:
Monoclonal
Conjugate:
PE/ATTO 594
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
CD33
Immunogen:
Human AML cells
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a 67kDa glycoprotein, which is identified as CD33 (HLDA IV; WS Code M-505). CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immuno-receptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.
Content And Storage:
Store at 4°C in the dark. Do not freeze.
Applications:
Flow Cytometry
Clone:
WM53
Dilution:
Flow Cytometry
Gene Alias:
CD33 antigen, CD33 antigen (gp67), CD33 molecule, FLJ00391, myeloid cell surface antigen CD33, p67, sialic acid binding Ig-like lectin 3, Sialic acid-binding Ig-like lectin 3, SIGLEC-3, SIGLEC3gp67
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Immunology
Gene ID (Entrez):
945.0
Target Species:
Human
Isotype:
IgG1 κ
Antigen: Siglec-3/CD33
Classification: Monoclonal
Conjugate: PE-Cyanine5.5
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: CD33
Immunogen: Human AML cells
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Recognizes a 67kDa glycoprotein, which is identified as CD33 (HLDA IV; WS Code M-505). CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immuno-receptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.
Content And Storage: Store at 4°C in the dark. Do not freeze.
Applications: Flow Cytometry
Clone: WM53
Dilution: Flow Cytometry
Gene Alias: CD33 antigen, CD33 antigen (gp67), CD33 molecule, FLJ00391, myeloid cell surface antigen CD33, p67, sialic acid binding Ig-like lectin 3, Sialic acid-binding Ig-like lectin 3, SIGLEC-3, SIGLEC3gp67
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Immunology
Gene ID (Entrez): 945.0
Target Species: Human
Isotype: IgG1 κ
Antigen:
Siglec-3/CD33
Classification:
Monoclonal
Conjugate:
PE-Cyanine5.5
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
CD33
Immunogen:
Human AML cells
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a 67kDa glycoprotein, which is identified as CD33 (HLDA IV; WS Code M-505). CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immuno-receptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.
Content And Storage:
Store at 4°C in the dark. Do not freeze.
Applications:
Flow Cytometry
Clone:
WM53
Dilution:
Flow Cytometry
Gene Alias:
CD33 antigen, CD33 antigen (gp67), CD33 molecule, FLJ00391, myeloid cell surface antigen CD33, p67, sialic acid binding Ig-like lectin 3, Sialic acid-binding Ig-like lectin 3, SIGLEC-3, SIGLEC3gp67
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Immunology
Gene ID (Entrez):
945.0
Target Species:
Human
Isotype:
IgG1 κ
Antigen: NCAM-1/CD56
Classification: Monoclonal
Conjugate: PE/ATTO 594
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: NCAM1
Immunogen: Membrane preparation of a small cell lung carcinoma
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
Content And Storage: Store at 4°C in the dark. Do not freeze.
Applications: Flow Cytometry
Clone: 123C3.D5 + 123A8
Dilution: Flow Cytometry
Gene Alias: CD56, CD56/ NCAM-1, CD56 antigen, MSK39, N-CAM-1, NCAM-1, NCAMantigen recognized by monoclonal 5.1H11, neural cell adhesion molecule 1, neural cell adhesion molecule, NCAM
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Astrocyte Markers, Cellular Markers, Cytokine Research, Cytoskeleton Markers, Growth and Development, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Membrane Vesicle Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers
Gene ID (Entrez): 4684.0
Target Species: Human
Isotype: IgG1 κ
Antigen:
NCAM-1/CD56
Classification:
Monoclonal
Conjugate:
PE/ATTO 594
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
NCAM1
Immunogen:
Membrane preparation of a small cell lung carcinoma
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
Content And Storage:
Store at 4°C in the dark. Do not freeze.
Applications:
Flow Cytometry
Clone:
123C3.D5 + 123A8
Dilution:
Flow Cytometry
Gene Alias:
CD56, CD56/ NCAM-1, CD56 antigen, MSK39, N-CAM-1, NCAM-1, NCAMantigen recognized by monoclonal 5.1H11, neural cell adhesion molecule 1, neural cell adhesion molecule, NCAM
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Astrocyte Markers, Cellular Markers, Cytokine Research, Cytoskeleton Markers, Growth and Development, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Membrane Vesicle Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers
Gene ID (Entrez):
4684.0
Target Species:
Human
Isotype:
IgG1 κ
Antigen: NCAM-1/CD56
Classification: Monoclonal
Conjugate: PE-Cyanine7
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: NCAM1
Immunogen: Membrane preparation of a small cell lung carcinoma
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
Content And Storage: Store at 4°C in the dark. Do not freeze.
Applications: Flow Cytometry
Clone: 123C3.D5 + 123A8
Dilution: Flow Cytometry
Gene Alias: CD56, CD56/ NCAM-1, CD56 antigen, MSK39, N-CAM-1, NCAM-1, NCAMantigen recognized by monoclonal 5.1H11, neural cell adhesion molecule 1, neural cell adhesion molecule, NCAM
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Astrocyte Markers, Cellular Markers, Cytokine Research, Cytoskeleton Markers, Growth and Development, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Membrane Vesicle Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers
Gene ID (Entrez): 4684.0
Target Species: Human
Isotype: IgG1 κ
Antigen:
NCAM-1/CD56
Classification:
Monoclonal
Conjugate:
PE-Cyanine7
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
NCAM1
Immunogen:
Membrane preparation of a small cell lung carcinoma
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
Content And Storage:
Store at 4°C in the dark. Do not freeze.
Applications:
Flow Cytometry
Clone:
123C3.D5 + 123A8
Dilution:
Flow Cytometry
Gene Alias:
CD56, CD56/ NCAM-1, CD56 antigen, MSK39, N-CAM-1, NCAM-1, NCAMantigen recognized by monoclonal 5.1H11, neural cell adhesion molecule 1, neural cell adhesion molecule, NCAM
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Astrocyte Markers, Cellular Markers, Cytokine Research, Cytoskeleton Markers, Growth and Development, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Membrane Vesicle Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers
Gene ID (Entrez):
4684.0
Target Species:
Human
Isotype:
IgG1 κ