N234547PEC7

Melanoma Marker (MART-1 + Tyrosinase + gp100) Mouse anti-Human, PE-Cyanine7, Clone: A103 + T311 + HMB45, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 N234547PEC7-Each-of-1 In Stock ₹ 57,410.76

N234547PEC7 - Each of 1

₹ 57,410.76

In Stock

Quantity

1

Base Price: ₹ 57,410.76

GST (18%): ₹ 10,333.937

Total Price: ₹ 67,744.697

Antigen

Melanoma Marker (MART-1 + Tyrosinase + gp100)

Classification

Monoclonal

Conjugate

PE-Cyanine7

Formulation

PBS with 0.05% Sodium Azide

Host Species

Mouse

Purification Method

Protein A or G purified

Primary or Secondary

Primary

Test Specificity

This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. The function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.

Content And Storage

Store at 4°C in the dark. Do not freeze.

Applications

Flow Cytometry

Clone

A103 + T311 + HMB45

Dilution

Flow Cytometry

Gene Alias

MART1, MART-1, melan-A, MLANA

Immunogen

Recombinant hMART-1 protein (A103); Recombinant tyrosinase protein (T311); Extract of pigmented melanoma metastases from lymph nodes (HMB45)

Quantity

0.1 mL

Gene ID (Entrez)

2315.0

Target Species

Human

Isotype

IgG1, IgG2a κ

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Description

  • Melanoma Marker (MART-1 + Tyrosinase + gp100) Monoclonal specifically detects Melanoma Marker (MART-1 + Tyrosinase + gp100) in Human samples
  • It is validated for Flow (Intracellular).

Compare Similar Items

Show Difference

Img

Novus Biologicals

N234547PEC7

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Antigen:
Melanoma Marker (MART-1 + Tyrosinase + gp100)

Classification:
Monoclonal

Conjugate:
PE-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Host Species:
Mouse

Purification Method:
Protein A or G purified

Primary or Secondary:
Primary

Test Specificity:
This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. The function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
A103 + T311 + HMB45

Dilution:
Flow Cytometry

Gene Alias:
MART1, MART-1, melan-A, MLANA

Immunogen:
Recombinant hMART-1 protein (A103); Recombinant tyrosinase protein (T311); Extract of pigmented melanoma metastases from lymph nodes (HMB45)

Quantity:
0.1 mL

Gene ID (Entrez):
2315.0

Target Species:
Human

Isotype:
IgG1, IgG2a κ

Img

Novus Biologicals

N234562P594

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Antigen:
Myeloid Cell Marker

Classification:
Monoclonal

Conjugate:
PE/ATTO 594

Formulation:
PBS with 0.05% Sodium Azide

Host Species:
Mouse

Purification Method:
Protein A or G purified

Primary or Secondary:
Primary

Test Specificity:
Recognizes 183kDa protein with DNA-binding characteristics, which is identified as a myeloid specific antigen. It reacts with myeloid precursor cells and granulocytes in bone marrow. Its antigen appears to be restricted to M2 and M3 acute myelogenous leukemia (AML) subtypes. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. This monoclonal antibody reacts with early precursor and mature forms of human myeloid cells. It is useful in the identification of myelogenous leukemias, distinguishing granulocytic sarcomas from lymphoid malignancies and also in the study of differentiation and transformation of human myeloid cells. The biological function of this antigen is not clear, although it has been proposed that it may play a role in the differentiation of myeloid cells.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
BM-1

Dilution:
Flow Cytometry

Gene Alias:
myeloid specific antigen, myeloid specific protein, p183 DNA-binding cytoplasmic ptotein

Immunogen:
Human peripheral blood mononuclear cells

Quantity:
0.1 mL

Gene ID (Entrez):
__

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

N234564P594

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Antigen:
CD45RB

Classification:
Monoclonal

Conjugate:
PE/ATTO 594

Formulation:
PBS with 0.05% Sodium Azide

Host Species:
Mouse

Purification Method:
Protein A or G purified

Primary or Secondary:
Primary

Test Specificity:
CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
BRA-11 (same as BRA-11G)

Dilution:
Flow Cytometry

Gene Alias:
B220, CD45 antigen, CD45R, EC 3.1.3.48, L-CA, LY5, protein tyrosine phosphatase, receptor type, C, receptor-type tyrosine-protein phosphatase C, T200 glycoprotein, T200 leukocyte common antigen, T200receptor type, c polypeptide

Immunogen:
Non-T, non-B CALLA positive ALL cell line REH (Leucocyte Workshop IV and V)

Quantity:
0.1 mL

Gene ID (Entrez):
5788.0

Target Species:
Human, Monkey (Negative), Rat (Negative)

Isotype:
IgG1 κ

Img

Novus Biologicals

N234564PEC5

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Antigen:
CD45RB

Classification:
Monoclonal

Conjugate:
PE-Cyanine5.5

Formulation:
PBS with 0.05% Sodium Azide

Host Species:
Mouse

Purification Method:
Protein A or G purified

Primary or Secondary:
Primary

Test Specificity:
CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
BRA-11 (same as BRA-11G)

Dilution:
Flow Cytometry

Gene Alias:
B220, CD45 antigen, CD45R, EC 3.1.3.48, L-CA, LY5, protein tyrosine phosphatase, receptor type, C, receptor-type tyrosine-protein phosphatase C, T200 glycoprotein, T200 leukocyte common antigen, T200receptor type, c polypeptide

Immunogen:
Non-T, non-B CALLA positive ALL cell line REH (Leucocyte Workshop IV and V)

Quantity:
0.1 mL

Gene ID (Entrez):
5788.0

Target Species:
Human, Monkey (Negative), Rat (Negative)

Isotype:
IgG1 κ