N234589PEC5
CD8 Antibody (C8/468), PE/Cy5.5, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | N234589PEC5-Each-of-1 | In Stock | ₹ 61,517.64 |
N234589PEC5 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 61,517.64
GST (18%): ₹ 11,073.175
Total Price: ₹ 72,590.815
Antigen
CD8
Classification
Monoclonal
Conjugate
PE-Cyanine5.5
Formulation
PBS with 0.05% Sodium Azide
Gene Symbols
CD8A
Immunogen
Human CD8 recombinant protein (Uniprot: P01732 )
Quantity
0.1 mL
Primary or Secondary
Primary
Test Specificity
CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.
Content And Storage
Store at 4°C in the dark. Do not freeze.
Applications
Flow Cytometry
Clone
C8/468
Dilution
Flow Cytometry
Gene Alias
CD8, CD8a molecule, LEU2, p32
Host Species
Mouse
Purification Method
Protein A or G purified
Research Discipline
Adaptive Immunity, Cytokine Research, Immunology, Immunophenotyping, Innate Immunity, Phospho Specific, Signal Transduction, Stem Cell Markers
Gene ID (Entrez)
925.0
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- CD8 Monoclonal specifically detects CD8 in Human samples
- It is validated for Flow Cytometry.
Compare Similar Items
Show Difference
Antigen: CD8
Classification: Monoclonal
Conjugate: PE-Cyanine5.5
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: CD8A
Immunogen: Human CD8 recombinant protein (Uniprot: P01732 )
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.
Content And Storage: Store at 4°C in the dark. Do not freeze.
Applications: Flow Cytometry
Clone: C8/468
Dilution: Flow Cytometry
Gene Alias: CD8, CD8a molecule, LEU2, p32
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Adaptive Immunity, Cytokine Research, Immunology, Immunophenotyping, Innate Immunity, Phospho Specific, Signal Transduction, Stem Cell Markers
Gene ID (Entrez): 925.0
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD8
Classification:
Monoclonal
Conjugate:
PE-Cyanine5.5
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
CD8A
Immunogen:
Human CD8 recombinant protein (Uniprot: P01732 )
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.
Content And Storage:
Store at 4°C in the dark. Do not freeze.
Applications:
Flow Cytometry
Clone:
C8/468
Dilution:
Flow Cytometry
Gene Alias:
CD8, CD8a molecule, LEU2, p32
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Adaptive Immunity, Cytokine Research, Immunology, Immunophenotyping, Innate Immunity, Phospho Specific, Signal Transduction, Stem Cell Markers
Gene ID (Entrez):
925.0
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD8
Classification: Monoclonal
Conjugate: PE-Cyanine7
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: CD8A
Immunogen: Human CD8 recombinant protein (Uniprot: P01732 )
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.
Content And Storage: Store at 4°C in the dark. Do not freeze.
Applications: Flow Cytometry
Clone: C8/468
Dilution: Flow Cytometry
Gene Alias: CD8, CD8a molecule, LEU2, p32
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Adaptive Immunity, Cytokine Research, Immunology, Immunophenotyping, Innate Immunity, Phospho Specific, Signal Transduction, Stem Cell Markers
Gene ID (Entrez): 925.0
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD8
Classification:
Monoclonal
Conjugate:
PE-Cyanine7
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
CD8A
Immunogen:
Human CD8 recombinant protein (Uniprot: P01732 )
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.
Content And Storage:
Store at 4°C in the dark. Do not freeze.
Applications:
Flow Cytometry
Clone:
C8/468
Dilution:
Flow Cytometry
Gene Alias:
CD8, CD8a molecule, LEU2, p32
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Adaptive Immunity, Cytokine Research, Immunology, Immunophenotyping, Innate Immunity, Phospho Specific, Signal Transduction, Stem Cell Markers
Gene ID (Entrez):
925.0
Target Species:
Human
Isotype:
IgG1 κ
Antigen: TAG-72
Classification: Monoclonal
Conjugate: PE/ATTO 594
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: __
Immunogen: Membrane-enriched fraction of a human breast carcinoma liver metastasis (B72.3); Purified TAG-72 protein (CC49)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This monoclonal antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.
Content And Storage: Store at 4°C in the dark. Do not freeze.
Applications: Flow Cytometry
Clone: B72.3 + CC49
Dilution: Flow Cytometry
Gene Alias: CA 72-4, Protein TAG-72, tag 72, tag-72 Protein TAG-72
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human, Rat, Bovine, Canine
Isotype: IgG1 κ
Antigen:
TAG-72
Classification:
Monoclonal
Conjugate:
PE/ATTO 594
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
__
Immunogen:
Membrane-enriched fraction of a human breast carcinoma liver metastasis (B72.3); Purified TAG-72 protein (CC49)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This monoclonal antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.
Content And Storage:
Store at 4°C in the dark. Do not freeze.
Applications:
Flow Cytometry
Clone:
B72.3 + CC49
Dilution:
Flow Cytometry
Gene Alias:
CA 72-4, Protein TAG-72, tag 72, tag-72 Protein TAG-72
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human, Rat, Bovine, Canine
Isotype:
IgG1 κ
Antigen: TAG-72
Classification: Monoclonal
Conjugate: PE-Cyanine5.5
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: __
Immunogen: Membrane-enriched fraction of a human breast carcinoma liver metastasis (B72.3); Purified TAG-72 protein (CC49)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This monoclonal antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.
Content And Storage: Store at 4°C in the dark. Do not freeze.
Applications: Flow Cytometry
Clone: B72.3 + CC49
Dilution: Flow Cytometry
Gene Alias: CA 72-4, Protein TAG-72, tag 72, tag-72 Protein TAG-72
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human, Rat, Bovine, Canine
Isotype: IgG1 κ
Antigen:
TAG-72
Classification:
Monoclonal
Conjugate:
PE-Cyanine5.5
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
__
Immunogen:
Membrane-enriched fraction of a human breast carcinoma liver metastasis (B72.3); Purified TAG-72 protein (CC49)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This monoclonal antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.
Content And Storage:
Store at 4°C in the dark. Do not freeze.
Applications:
Flow Cytometry
Clone:
B72.3 + CC49
Dilution:
Flow Cytometry
Gene Alias:
CA 72-4, Protein TAG-72, tag 72, tag-72 Protein TAG-72
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human, Rat, Bovine, Canine
Isotype:
IgG1 κ