N234658PEC7

VEGFR2/KDR/Flk-1 Antibody (KDR721), PE/Cy7, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 N234658PEC7-Each-of-1 In Stock ₹ 60,448.14

N234658PEC7 - Each of 1

₹ 60,448.14

In Stock

Quantity

1

Base Price: ₹ 60,448.14

GST (18%): ₹ 10,880.665

Total Price: ₹ 71,328.805

Antigen

VEGFR2/KDR/Flk-1

Classification

Monoclonal

Conjugate

PE-Cyanine7

Formulation

PBS with 0.05% Sodium Azide

Gene Symbols

KDR

Immunogen

Recombinant human VEGFR2/KDR/Flk-1 protein (Uniprot: P35968)

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

CD309, also known as VEGFR2, KDR3, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGFR2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGFR2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGFR2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.

Content And Storage

Store at 4°C in the dark. Do not freeze.

Applications

Flow Cytometry

Clone

KDR721

Dilution

Flow Cytometry

Gene Alias

CD309, CD309 antigen, EC 2.7.10, EC 2.7.10.1, Fetal liver kinase 1, fetal liver kinase-1, FLK-1, FLK1tyrosine kinase growth factor receptor, Kinase insert domain receptor, kinase insert domain receptor (a type III receptor tyrosine kinase), Protein-tyrosine kinase receptor flk-1, soluble VEGFR2, vascular endothelial growth factor receptor 2, VEGFR, VEGFR2, VEGFR-2

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Angiogenesis, Apoptosis, Cancer, Cellular Markers, Cytoskeleton Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, HIF Target Genes, Hypoxia, Phospho Specific, Signal Transduction, Stem Cell Markers, Tumor Suppressors, Tyrosine Kinases

Gene ID (Entrez)

3791.0

Target Species

Human

Isotype

IgG1 κ

Related Products

Img

Novus Biologicals

N234658PEC5

--

Img

Novus Biologicals

N234658APC7

--

Img

Novus Biologicals

N118646PEC5

--

Img

Novus Biologicals

N118644APC7

--

Img

Novus Biologicals

N118644PEC5

--

Img

Novus Biologicals

N236428PEC7

--

Img

Novus Biologicals

N236428APC7

--

Img

Novus Biologicals

N236428PEC5

--

Description

  • VEGFR2/KDR/Flk-1 Monoclonal specifically detects VEGFR2/KDR/Flk-1 in Human samples
  • It is validated for Flow Cytometry.

Compare Similar Items

Show Difference

Img

Novus Biologicals

N234658PEC7

--


Antigen:
VEGFR2/KDR/Flk-1

Classification:
Monoclonal

Conjugate:
PE-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
KDR

Immunogen:
Recombinant human VEGFR2/KDR/Flk-1 protein (Uniprot: P35968)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
CD309, also known as VEGFR2, KDR3, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGFR2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGFR2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGFR2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
KDR721

Dilution:
Flow Cytometry

Gene Alias:
CD309, CD309 antigen, EC 2.7.10, EC 2.7.10.1, Fetal liver kinase 1, fetal liver kinase-1, FLK-1, FLK1tyrosine kinase growth factor receptor, Kinase insert domain receptor, kinase insert domain receptor (a type III receptor tyrosine kinase), Protein-tyrosine kinase receptor flk-1, soluble VEGFR2, vascular endothelial growth factor receptor 2, VEGFR, VEGFR2, VEGFR-2

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Angiogenesis, Apoptosis, Cancer, Cellular Markers, Cytoskeleton Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, HIF Target Genes, Hypoxia, Phospho Specific, Signal Transduction, Stem Cell Markers, Tumor Suppressors, Tyrosine Kinases

Gene ID (Entrez):
3791.0

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

N234659APC7

--


Antigen:
Kappa Light Chain

Classification:
Monoclonal

Conjugate:
APC-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
IGKC

Immunogen:
Recombinant human Ig kappa chain

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
KLC264

Dilution:
Flow Cytometry

Gene Alias:
HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Adaptive Immunity, Immunology

Gene ID (Entrez):
3514.0

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

N234659PEC7

--


Antigen:
Kappa Light Chain

Classification:
Monoclonal

Conjugate:
PE-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
IGKC

Immunogen:
Recombinant human Ig kappa chain

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
KLC264

Dilution:
Flow Cytometry

Gene Alias:
HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Adaptive Immunity, Immunology

Gene ID (Entrez):
3514.0

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

N234680APC7

--


Antigen:
Melan-A/MART-1

Classification:
Monoclonal

Conjugate:
APC-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
MLANA

Immunogen:
Recombinant full-length hMelan-A/MART-1 protein (M2-7C10; M2-9E3) (Uniprot: Q16655)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This monoclonal antibody labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
M2-7C10 + M2-9E3

Dilution:
Flow Cytometry, Flow (Intracellular)

Gene Alias:
Antigen LB39-AA, Antigen SK29-AA, Mart 1 Melan A, MART1MART-1, melan-A, melanoma antigen recognized by T-cells 1, Protein Melan-A

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Cytoskeleton Markers, Immunology

Gene ID (Entrez):
2315.0

Target Species:
Human, Mouse, Rat

Isotype:
IgG2b κ