N234708PEC7

CD45RB Antibody (PD7/26), PE/Cy7, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 N234708PEC7-Each-of-1 In Stock ₹ 60,448.14

N234708PEC7 - Each of 1

₹ 60,448.14

In Stock

Quantity

1

Base Price: ₹ 60,448.14

GST (18%): ₹ 10,880.665

Total Price: ₹ 71,328.805

Antigen

CD45RB

Classification

Monoclonal

Conjugate

PE-Cyanine7

Formulation

PBS with 0.05% Sodium Azide

Gene Symbols

PTPRC

Immunogen

Human peripheral blood lymphocytes maintained in T cell growth factor

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin.

Content And Storage

Store at 4°C in the dark. Do not freeze.

Applications

Flow Cytometry

Clone

PD7/26

Dilution

Flow Cytometry

Gene Alias

B220, CD45 antigen, CD45R, EC 3.1.3.48, L-CA, LY5, protein tyrosine phosphatase, receptor type, C, receptor-type tyrosine-protein phosphatase C, T200 glycoprotein, T200 leukocyte common antigen, T200receptor type, c polypeptide

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Adaptive Immunity, Cell Biology, Cellular Markers, Cytokine Research, Hematopoietic Stem Cell Markers, Immunology, Mesenchymal Stem Cell Markers, Microglia Markers, Neuronal Cell Markers, Neuroscience, Signal Transduction, Stem Cell Markers

Gene ID (Entrez)

5788.0

Target Species

Human

Isotype

IgG1 κ

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Description

  • CD45RB Monoclonal specifically detects CD45RB in Human samples
  • It is validated for Flow Cytometry.

Compare Similar Items

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Novus Biologicals

N234708PEC7

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Antigen:
CD45RB

Classification:
Monoclonal

Conjugate:
PE-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
PTPRC

Immunogen:
Human peripheral blood lymphocytes maintained in T cell growth factor

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
PD7/26

Dilution:
Flow Cytometry

Gene Alias:
B220, CD45 antigen, CD45R, EC 3.1.3.48, L-CA, LY5, protein tyrosine phosphatase, receptor type, C, receptor-type tyrosine-protein phosphatase C, T200 glycoprotein, T200 leukocyte common antigen, T200receptor type, c polypeptide

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Adaptive Immunity, Cell Biology, Cellular Markers, Cytokine Research, Hematopoietic Stem Cell Markers, Immunology, Mesenchymal Stem Cell Markers, Microglia Markers, Neuronal Cell Markers, Neuroscience, Signal Transduction, Stem Cell Markers

Gene ID (Entrez):
5788.0

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

N234715PEC5

--


Antigen:
Erythrocyte Specific

Classification:
Monoclonal

Conjugate:
PE-Cyanine5.5

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
__

Immunogen:
Hepatocytes from 20-22 week-old human fetus

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Mouse Anti-Human Erythrocytes Clone SFL23.6 monoclonal antibody is directed against an erythroid cell surface antigen. It shows a well-defined reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. Although the exact identity of the antigen has yet to be determined, it has been shown to be distinct from Glycophorin A. This monoclonal antibody is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
SFL23.6

Dilution:
Flow Cytometry

Gene Alias:
erythroid cell surface antigen

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
Human

Isotype:
IgG2b κ

Img

Novus Biologicals

N234715PEC7

--


Antigen:
Erythrocyte Specific

Classification:
Monoclonal

Conjugate:
PE-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
__

Immunogen:
Hepatocytes from 20-22 week-old human fetus

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Mouse Anti-Human Erythrocytes Clone SFL23.6 monoclonal antibody is directed against an erythroid cell surface antigen. It shows a well-defined reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. Although the exact identity of the antigen has yet to be determined, it has been shown to be distinct from Glycophorin A. This monoclonal antibody is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
SFL23.6

Dilution:
Flow Cytometry

Gene Alias:
erythroid cell surface antigen

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
Human

Isotype:
IgG2b κ

Img

Novus Biologicals

N234717P594

--


Antigen:
SUMO2/3

Classification:
Monoclonal

Conjugate:
PE/ATTO 594

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
SUMO2

Immunogen:
Recombinant human SUMO2 protein

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with both SUMO-2 and SUMO-3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, 2 and 3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2 and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1, 2 and 3 proteins localize to the nuclear membrane, nuclear bodies and cytoplasm, respectively. SUMO-1 utilizes Ubc9 for conjugation to several target proteins, which include MDM2, p53, PML and RanGap1. SUMO-2 and 3 contribute to a greater percentage of protein modification than does SUMO-1

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
SM23/496

Dilution:
Flow Cytometry, Flow (Intracellular)

Gene Alias:
HSMT3, small ubiquitin-like modifier 2, SMT3A, SMT3B, SMT3H2, SUMO2, SUMO3

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Apoptosis

Gene ID (Entrez):
6613.0

Target Species:
Human

Isotype:
IgG1 κ