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N247721PEC5

HLA DQ Mouse anti-Human, Porcine, PE/Cy5.5, Clone: SPM422, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 N247721PEC5-Each-of-1 In Stock ₹ 57,410.76

N247721PEC5 - Each of 1

₹ 57,410.76

In Stock

Quantity

1

Base Price: ₹ 57,410.76

GST (18%): ₹ 10,333.937

Total Price: ₹ 67,744.697

Antigen

HLA DQ

Classification

Monoclonal

Conjugate

PE-Cyanine5.5

Formulation

PBS with 0.05% Sodium Azide

Gene Symbols

HLA-DQA1

Immunogen

T4-positive CTL clone HG-38

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

Recognizes a DQ antigen, which is a dimer of 60kDa. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.

Content And Storage

Store at 4°C in the dark. Do not freeze.

Applications

Flow Cytometry

Clone

SPM422

Dilution

Flow Cytometry

Gene Alias

CD, CELIAC1DQ alpha 1 chain, DC-1 alpha chain, DQ-A1, FLJ27088, FLJ27328, GSE, HLA class II histocompatibility antigen, DQ(W3) alpha chain, HLA-DCA, HLA-DQA, leucocyte antigen DQA1, leukocyte antigen alpha chain, major histocompatibility complex, class II, DQ alpha 1, MGC149527, MHC class II antigen, MHC class II DQA1, MHC class II HLA-D alpha glycoprotein, MHC class II HLA-DQ-alpha-1, MHC class II surface glycoprotein, MHC HLA-DQ alpha

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Adaptive Immunity, Asthma, Immunology

Gene ID (Entrez)

3117.0

Target Species

Human, Porcine

Isotype

IgG2a κ

Description

  • HLA DQ Monoclonal specifically detects HLA DQ in Human, Porcine samples
  • It is validated for Flow Cytometry.

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Novus Biologicals

N247721PEC5

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Antigen:
HLA DQ
Classification:
Monoclonal
Conjugate:
PE-Cyanine5.5
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
HLA-DQA1
Immunogen:
T4-positive CTL clone HG-38
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a DQ antigen, which is a dimer of 60kDa. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.
Content And Storage:
Store at 4°C in the dark. Do not freeze.
Applications:
Flow Cytometry
Clone:
SPM422
Dilution:
Flow Cytometry
Gene Alias:
CD, CELIAC1DQ alpha 1 chain, DC-1 alpha chain, DQ-A1, FLJ27088, FLJ27328, GSE, HLA class II histocompatibility antigen, DQ(W3) alpha chain, HLA-DCA, HLA-DQA, leucocyte antigen DQA1, leukocyte antigen alpha chain, major histocompatibility complex, class II, DQ alpha 1, MGC149527, MHC class II antigen, MHC class II DQA1, MHC class II HLA-D alpha glycoprotein, MHC class II HLA-DQ-alpha-1, MHC class II surface glycoprotein, MHC HLA-DQ alpha
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Adaptive Immunity, Asthma, Immunology
Gene ID (Entrez):
3117.0
Target Species:
Human, Porcine
Isotype:
IgG2a κ

Img

Novus Biologicals

N247722PEC7

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Antigen:
HLA DRA
Classification:
Monoclonal
Conjugate:
PE-Cyanine7
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
HLA-DRA
Immunogen:
Human peripheral blood leukocytes (Uniprot: P01903)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.
Content And Storage:
Store at 4°C in the dark. Do not freeze.
Applications:
Flow Cytometry
Clone:
169-1B5.2
Dilution:
Flow Cytometry
Gene Alias:
FLJ51114, histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA1, major histocompatibility complex, class II, DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, MLRW
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Adaptive Immunity, Cell Biology, Diabetes Research, Immunology
Gene ID (Entrez):
3122.0
Target Species:
Human, Bovine, Feline
Isotype:
IgG2b κ

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Novus Biologicals

N247723APC7

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Antigen:
IgM
Classification:
Monoclonal
Conjugate:
APC-Cyanine7
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
IGHM
Immunogen:
Heavy chain of human IgM
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 75kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. IgM antibody is prominent in early immune responses to most antigens. Aberrant levels are associated with immune deficiency states, hereditary deficiencies, myeloma, Waldenstroms lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Content And Storage:
Store at 4°C in the dark. Do not freeze.
Applications:
Flow Cytometry
Clone:
ICO-30
Dilution:
Flow Cytometry
Gene Alias:
AGM1, DKFZp686I15196, DKFZp686I15212, FLJ00385, immunoglobulin heavy constant mu, MGC104996, MGC52291, MU, VH
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
B Cell Development and Differentiation Markers, Immunology
Gene ID (Entrez):
3507.0
Target Species:
Human
Isotype:
IgG1 κ

Img

Novus Biologicals

N247723PEC7

--

Antigen:
IgM
Classification:
Monoclonal
Conjugate:
PE-Cyanine7
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
IGHM
Immunogen:
Heavy chain of human IgM
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 75kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. IgM antibody is prominent in early immune responses to most antigens. Aberrant levels are associated with immune deficiency states, hereditary deficiencies, myeloma, Waldenstroms lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Content And Storage:
Store at 4°C in the dark. Do not freeze.
Applications:
Flow Cytometry
Clone:
ICO-30
Dilution:
Flow Cytometry
Gene Alias:
AGM1, DKFZp686I15196, DKFZp686I15212, FLJ00385, immunoglobulin heavy constant mu, MGC104996, MGC52291, MU, VH
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
B Cell Development and Differentiation Markers, Immunology
Gene ID (Entrez):
3507.0
Target Species:
Human
Isotype:
IgG1 κ