CCR5 Antibody (12D1), PE/Cy5.5, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | N247759PEC5-Each-of-1 | In Stock | ₹ 61,517.64 |
N247759PEC5 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 61,517.64
GST (18%): ₹ 11,073.175
Total Price: ₹ 72,590.815
Antigen
CCR5
Classification
Monoclonal
Conjugate
PE-Cyanine5.5
Formulation
PBS with 0.05% Sodium Azide
Gene Symbols
CCR5
Immunogen
Human native CCR5 protein (Uniprot: P51681)
Quantity
0.1 mL
Primary or Secondary
Primary
Test Specificity
Reacts with the N-terminal extracellular domain of CD195. The CC chemokine receptor 5 (CCR5) is a member of the CC-chemokine receptor family, and has the characteristic structure of a 7 transmembrane G protein-coupled receptor (GPCR). CCR5 regulates trafficking and effector functions of memory/effector Th1 cells, macrophages, NK cells, and immature dendritic cells. CCR5 and its ligands play an important role in viral pathogenesis. CCR5 represents the co-receptor for macrophage (M) and dual (T cell and M)-tropic immunodeficiency viruses. Together with the CD4 binding receptor, CCR5 plays a critical role in HIV entry into the target cells. Moreover, the CCR5 ligands macrophage inflammatory protein (MIP)-1 alpha, MIP-1 beta and RANTES act as endogenous inhibitors of HIV infection, making both CCR5 and its chemokine ligands attractive therapeutic targets for HIV infection. Recent studies have also highlighted the role of CCR5 in a variety of other human diseases, ranging from infectious an
Content And Storage
Store at 4°C in the dark. Do not freeze.
Applications
Flow Cytometry
Clone
12D1
Dilution
Flow Cytometry
Gene Alias
C-C CKR-5, C-C motif chemokine receptor 5 A159A, CCCKR5, CC-CKR-5FLJ78003, CCR-5, CD195, CD195 antigen, chemokine (C-C motif) receptor 5, chemokine receptor CCR5, chemr13, CKR5, CKR-5, HIV-1 fusion coreceptor, IDDM22CMKBR5C-C chemokine receptor type 5
Host Species
Mouse
Purification Method
Protein A or G purified
Research Discipline
Alzheimers Research, Cancer, Chemokine Research, Chemokines and Cytokines, Cytokine Research, GPCR, Immunology, Innate Immunity, Neurodegeneration, Neuroscience, Phospho Specific, Signal Transduction
Gene ID (Entrez)
1234.0
Target Species
Human
Isotype
IgG2a κ
Description
- CCR5 Monoclonal specifically detects CCR5 in Human samples
- It is validated for Flow Cytometry.
Compare Similar Items
Show Difference
Antigen: CCR5
Classification: Monoclonal
Conjugate: PE-Cyanine5.5
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: CCR5
Immunogen: Human native CCR5 protein (Uniprot: P51681)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Reacts with the N-terminal extracellular domain of CD195. The CC chemokine receptor 5 (CCR5) is a member of the CC-chemokine receptor family, and has the characteristic structure of a 7 transmembrane G protein-coupled receptor (GPCR). CCR5 regulates trafficking and effector functions of memory/effector Th1 cells, macrophages, NK cells, and immature dendritic cells. CCR5 and its ligands play an important role in viral pathogenesis. CCR5 represents the co-receptor for macrophage (M) and dual (T cell and M)-tropic immunodeficiency viruses. Together with the CD4 binding receptor, CCR5 plays a critical role in HIV entry into the target cells. Moreover, the CCR5 ligands macrophage inflammatory protein (MIP)-1 alpha, MIP-1 beta and RANTES act as endogenous inhibitors of HIV infection, making both CCR5 and its chemokine ligands attractive therapeutic targets for HIV infection. Recent studies have also highlighted the role of CCR5 in a variety of other human diseases, ranging from infectious an
Content And Storage: Store at 4°C in the dark. Do not freeze.
Applications: Flow Cytometry
Clone: 12D1
Dilution: Flow Cytometry
Gene Alias: C-C CKR-5, C-C motif chemokine receptor 5 A159A, CCCKR5, CC-CKR-5FLJ78003, CCR-5, CD195, CD195 antigen, chemokine (C-C motif) receptor 5, chemokine receptor CCR5, chemr13, CKR5, CKR-5, HIV-1 fusion coreceptor, IDDM22CMKBR5C-C chemokine receptor type 5
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Alzheimers Research, Cancer, Chemokine Research, Chemokines and Cytokines, Cytokine Research, GPCR, Immunology, Innate Immunity, Neurodegeneration, Neuroscience, Phospho Specific, Signal Transduction
Gene ID (Entrez): 1234.0
Target Species: Human
Isotype: IgG2a κ
Antigen: CD90/Thy1
Classification: Monoclonal
Conjugate: PE/ATTO 594
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: THY1
Immunogen: Human T-lymphoma cells
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 18-35kDa, identified as CD90 (also known as Thy1). CD90 is a member of the immunoglobulin superfamily. It may contribute to inhibition of proliferation/differentiation of hematopoietic stem cells and neuron memory formation in the CNS. It consists of a single Ig domain (112 amino acids; 25-35 kDa) inserted into the cell membrane via a GPI anchor. Expressed by hematopoietic stem cells and neurons in all species studied. Its highly expressed in connective tissue and various fibroblast and stromal cell lines, expressed on all thymocytes and peripheral T cells in mice, but in humans expressed only on small % fetal thymocytes, 10-40% of CD34+ cells in bone marrow, and <1% of CD3+CD4+ lymphocytes in peripheral circulation. It is also expressed by human lymph node HEV endothelium but not other endothelia. Lastly, it is expressed by a limited number of lymphoblastoid and leukemic cell lines.
Content And Storage: Store at 4°C in the dark. Do not freeze.
Applications: Flow Cytometry
Clone: AF-9
Dilution: Flow Cytometry
Gene Alias: CD90, CD90 antigen, CDw90, FLJ33325, Thy-1 antigen, Thy-1 cell surface antigen, thy-1 membrane glycoprotein, Thy-1 T-cell antigen
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Hematopoietic Stem Cell Markers, Hepatic Stem Cell Markers, Immunology, Innate Immunity, Mesenchymal Stem Cell Markers, Signal Transduction, Stem Cell Markers
Gene ID (Entrez): 7070.0
Target Species: Human, Bovine
Isotype: IgG1 κ
Antigen: CD90/Thy1
Classification: Monoclonal
Conjugate: PE-Cyanine5.5
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: THY1
Immunogen: Human T-lymphoma cells
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 18-35kDa, identified as CD90 (also known as Thy1). CD90 is a member of the immunoglobulin superfamily. It may contribute to inhibition of proliferation/differentiation of hematopoietic stem cells and neuron memory formation in the CNS. It consists of a single Ig domain (112 amino acids; 25-35 kDa) inserted into the cell membrane via a GPI anchor. Expressed by hematopoietic stem cells and neurons in all species studied. Its highly expressed in connective tissue and various fibroblast and stromal cell lines, expressed on all thymocytes and peripheral T cells in mice, but in humans expressed only on small % fetal thymocytes, 10-40% of CD34+ cells in bone marrow, and <1% of CD3+CD4+ lymphocytes in peripheral circulation. It is also expressed by human lymph node HEV endothelium but not other endothelia. Lastly, it is expressed by a limited number of lymphoblastoid and leukemic cell lines.
Content And Storage: Store at 4°C in the dark. Do not freeze.
Applications: Flow Cytometry
Clone: AF-9
Dilution: Flow Cytometry
Gene Alias: CD90, CD90 antigen, CDw90, FLJ33325, Thy-1 antigen, Thy-1 cell surface antigen, thy-1 membrane glycoprotein, Thy-1 T-cell antigen
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Hematopoietic Stem Cell Markers, Hepatic Stem Cell Markers, Immunology, Innate Immunity, Mesenchymal Stem Cell Markers, Signal Transduction, Stem Cell Markers
Gene ID (Entrez): 7070.0
Target Species: Human, Bovine
Isotype: IgG1 κ