N24780PE594

CD43/Sialophorin Antibody (SPN/1094), PE/Atto594, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 N24780PE594-Each-of-1 In Stock ₹ 60,448.14

N24780PE594 - Each of 1

₹ 60,448.14

In Stock

Quantity

1

Base Price: ₹ 60,448.14

GST (18%): ₹ 10,880.665

Total Price: ₹ 71,328.805

Antigen

CD43/Sialophorin

Classification

Monoclonal

Conjugate

PE/ATTO 594

Formulation

PBS with 0.05% Sodium Azide

Gene Symbols

SPN

Immunogen

Recombinant full-length human CD43/Sialophorin protein (Uniprot: P16150)

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.

Content And Storage

Store at 4°C in the dark. Do not freeze.

Applications

Flow Cytometry

Clone

SPN/1094

Dilution

Flow Cytometry

Gene Alias

CD43 antigen, CD43), Galactoglycoprotein, GALGP, Leukocyte sialoglycoprotein, Sialophorin, sialophorin (gpL115, leukosialin, CD43)

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

B Cell Development and Differentiation Markers, Immunology

Gene ID (Entrez)

6693.0

Target Species

Human

Isotype

IgG1 κ

Description

  • CD43/Sialophorin Monoclonal specifically detects CD43/Sialophorin in Human samples
  • It is validated for Flow Cytometry.

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Novus Biologicals

N24780PE594

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Antigen:
CD43/Sialophorin

Classification:
Monoclonal

Conjugate:
PE/ATTO 594

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
SPN

Immunogen:
Recombinant full-length human CD43/Sialophorin protein (Uniprot: P16150)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
SPN/1094

Dilution:
Flow Cytometry

Gene Alias:
CD43 antigen, CD43), Galactoglycoprotein, GALGP, Leukocyte sialoglycoprotein, Sialophorin, sialophorin (gpL115, leukosialin, CD43)

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
B Cell Development and Differentiation Markers, Immunology

Gene ID (Entrez):
6693.0

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

N24780PECY7

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Antigen:
CD43/Sialophorin

Classification:
Monoclonal

Conjugate:
PE-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
SPN

Immunogen:
Recombinant full-length human CD43/Sialophorin protein (Uniprot: P16150)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
SPN/1094

Dilution:
Flow Cytometry

Gene Alias:
CD43 antigen, CD43), Galactoglycoprotein, GALGP, Leukocyte sialoglycoprotein, Sialophorin, sialophorin (gpL115, leukosialin, CD43)

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
B Cell Development and Differentiation Markers, Immunology

Gene ID (Entrez):
6693.0

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

N247812APC7

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Antigen:
CD47

Classification:
Monoclonal

Conjugate:
APC-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
CD47

Immunogen:
Recombinant human CD47 protein (CD47/964); Intact CD47 Purified from placenta (B6H12.2) (Uniprot: Q08722)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
IAP/964 + B6H12.2

Dilution:
Flow Cytometry, Flow (Cell Surface)

Gene Alias:
antigen identified by monoclonal 1D8, Antigenic surface determinant protein OA3, CD47 antigen, CD47 antigen (Rh-related antigen, integrin-associated signal transducer), CD47 glycoprotein, CD47 molecule, IAPintegrin associated protein, Integrin-associated protein, leukocyte surface antigen CD47, MER6integrin-associated signal transducer, OA3, Protein MER6, Rh-related antigen

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Immunology, Signal Transduction

Gene ID (Entrez):
961.0

Target Species:
Human, Mouse

Isotype:
IgG1 κ

Img

Novus Biologicals

N247812PEC5

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Antigen:
CD47

Classification:
Monoclonal

Conjugate:
PE-Cyanine5.5

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
CD47

Immunogen:
Recombinant human CD47 protein (CD47/964); Intact CD47 Purified from placenta (B6H12.2) (Uniprot: Q08722)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
IAP/964 + B6H12.2

Dilution:
Flow Cytometry, Flow (Cell Surface)

Gene Alias:
antigen identified by monoclonal 1D8, Antigenic surface determinant protein OA3, CD47 antigen, CD47 antigen (Rh-related antigen, integrin-associated signal transducer), CD47 glycoprotein, CD47 molecule, IAPintegrin associated protein, Integrin-associated protein, leukocyte surface antigen CD47, MER6integrin-associated signal transducer, OA3, Protein MER6, Rh-related antigen

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Immunology, Signal Transduction

Gene ID (Entrez):
961.0

Target Species:
Human, Mouse

Isotype:
IgG1 κ