N247826PEC5

NCAM-1/CD56 Antibody (NCAM1/795), PE/Cy5.5, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 N247826PEC5-Each-of-1 In Stock ₹ 60,448.14

N247826PEC5 - Each of 1

₹ 60,448.14

In Stock

Quantity

1

Base Price: ₹ 60,448.14

GST (18%): ₹ 10,880.665

Total Price: ₹ 71,328.805

Antigen

NCAM-1/CD56

Classification

Monoclonal

Conjugate

PE-Cyanine5.5

Formulation

PBS with 0.05% Sodium Azide

Gene Symbols

NCAM1

Immunogen

Recombinant human NCAM1 protein

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

This monoclonal antibody reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.

Content And Storage

Store at 4°C in the dark. Do not freeze.

Applications

Flow Cytometry

Clone

NCAM1/795

Dilution

Flow Cytometry

Gene Alias

CD56, CD56/ NCAM-1, CD56 antigen, MSK39, N-CAM-1, NCAM-1, NCAMantigen recognized by monoclonal 5.1H11, neural cell adhesion molecule 1, neural cell adhesion molecule, NCAM

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Astrocyte Markers, Cellular Markers, Cytokine Research, Cytoskeleton Markers, Growth and Development, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Membrane Vesicle Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers

Gene ID (Entrez)

4684.0

Target Species

Human

Isotype

IgG1 κ

Description

  • NCAM-1/CD56 Monoclonal specifically detects NCAM-1/CD56 in Human, Rat samples
  • It is validated for Flow Cytometry.

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Novus Biologicals

N247826PEC5

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Antigen:
NCAM-1/CD56

Classification:
Monoclonal

Conjugate:
PE-Cyanine5.5

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
NCAM1

Immunogen:
Recombinant human NCAM1 protein

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
NCAM1/795

Dilution:
Flow Cytometry

Gene Alias:
CD56, CD56/ NCAM-1, CD56 antigen, MSK39, N-CAM-1, NCAM-1, NCAMantigen recognized by monoclonal 5.1H11, neural cell adhesion molecule 1, neural cell adhesion molecule, NCAM

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Astrocyte Markers, Cellular Markers, Cytokine Research, Cytoskeleton Markers, Growth and Development, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Membrane Vesicle Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers

Gene ID (Entrez):
4684.0

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

N247830APC7

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Antigen:
Fc gamma RIIA/CD32a

Classification:
Monoclonal

Conjugate:
APC-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
FCGR2A

Immunogen:
K562 and FcgRII+L cells

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with a CD32 (FcgRII) epitope (cluster-4). It displays a stronger reaction with Daudi than with U937 cells. The epitope is located in domain 2 of FcgRIIa. Its Fab'2 fragments block immune complex binding. CD32 (FcRII) is a type 1 transmembrane glycoprotein that mediates several functions including phagocytosis, cytotoxicity, and immunomodulation as well as platelet aggregation. Three genes (A, B, and C) encode CD32 and at least 6 isoforms are generated via alternative mRNA splicing, i.e., IIa1, IIa2, IIb1, IIb2, IIb3 and IIc. Monocytes/macrophages, placental trophoblasts and endothelial cells express all isoforms. In addition, the IIb isoform is expressed by B cells, and the IIa isoform by platelets, granulocytes and, weakly, by B cells. NK cells and neutrophils express Isoform IIc. CD32 binds weakly to the Fc region of monomeric IgG but more strongly to IgG aggregates and immune complexes.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
7.3

Dilution:
Flow Cytometry

Gene Alias:
CD32 antigen, CD32A, CD32MGC23887, CDw32fc-gamma-RIIa, Fc fragment of IgG, low affinity IIa, receptor (CD32), Fc fragment of IgG, low affinity IIa, receptor for (CD32), FCG2, Fc-gamma RII-a, Fc-gamma-RIIa, FcGR, FCGR2, FCGR2A1, FcRII-a, IGFR2MGC30032, IgG Fc receptor II-a, Immunoglobulin G Fc receptor II, low affinity immunoglobulin gamma Fc region receptor II-a

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Immunology

Gene ID (Entrez):
2212.0

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

N247830P594

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Antigen:
Fc gamma RIIA/CD32a

Classification:
Monoclonal

Conjugate:
PE/ATTO 594

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
FCGR2A

Immunogen:
K562 and FcgRII+L cells

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with a CD32 (FcgRII) epitope (cluster-4). It displays a stronger reaction with Daudi than with U937 cells. The epitope is located in domain 2 of FcgRIIa. Its Fab'2 fragments block immune complex binding. CD32 (FcRII) is a type 1 transmembrane glycoprotein that mediates several functions including phagocytosis, cytotoxicity, and immunomodulation as well as platelet aggregation. Three genes (A, B, and C) encode CD32 and at least 6 isoforms are generated via alternative mRNA splicing, i.e., IIa1, IIa2, IIb1, IIb2, IIb3 and IIc. Monocytes/macrophages, placental trophoblasts and endothelial cells express all isoforms. In addition, the IIb isoform is expressed by B cells, and the IIa isoform by platelets, granulocytes and, weakly, by B cells. NK cells and neutrophils express Isoform IIc. CD32 binds weakly to the Fc region of monomeric IgG but more strongly to IgG aggregates and immune complexes.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
7.3

Dilution:
Flow Cytometry

Gene Alias:
CD32 antigen, CD32A, CD32MGC23887, CDw32fc-gamma-RIIa, Fc fragment of IgG, low affinity IIa, receptor (CD32), Fc fragment of IgG, low affinity IIa, receptor for (CD32), FCG2, Fc-gamma RII-a, Fc-gamma-RIIa, FcGR, FCGR2, FCGR2A1, FcRII-a, IGFR2MGC30032, IgG Fc receptor II-a, Immunoglobulin G Fc receptor II, low affinity immunoglobulin gamma Fc region receptor II-a

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Immunology

Gene ID (Entrez):
2212.0

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

N247830PEC5

--


Antigen:
Fc gamma RIIA/CD32a

Classification:
Monoclonal

Conjugate:
PE-Cyanine5.5

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
FCGR2A

Immunogen:
K562 and FcgRII+L cells

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with a CD32 (FcgRII) epitope (cluster-4). It displays a stronger reaction with Daudi than with U937 cells. The epitope is located in domain 2 of FcgRIIa. Its Fab'2 fragments block immune complex binding. CD32 (FcRII) is a type 1 transmembrane glycoprotein that mediates several functions including phagocytosis, cytotoxicity, and immunomodulation as well as platelet aggregation. Three genes (A, B, and C) encode CD32 and at least 6 isoforms are generated via alternative mRNA splicing, i.e., IIa1, IIa2, IIb1, IIb2, IIb3 and IIc. Monocytes/macrophages, placental trophoblasts and endothelial cells express all isoforms. In addition, the IIb isoform is expressed by B cells, and the IIa isoform by platelets, granulocytes and, weakly, by B cells. NK cells and neutrophils express Isoform IIc. CD32 binds weakly to the Fc region of monomeric IgG but more strongly to IgG aggregates and immune complexes.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
7.3

Dilution:
Flow Cytometry

Gene Alias:
CD32 antigen, CD32A, CD32MGC23887, CDw32fc-gamma-RIIa, Fc fragment of IgG, low affinity IIa, receptor (CD32), Fc fragment of IgG, low affinity IIa, receptor for (CD32), FCG2, Fc-gamma RII-a, Fc-gamma-RIIa, FcGR, FCGR2, FCGR2A1, FcRII-a, IGFR2MGC30032, IgG Fc receptor II-a, Immunoglobulin G Fc receptor II, low affinity immunoglobulin gamma Fc region receptor II-a

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Immunology

Gene ID (Entrez):
2212.0

Target Species:
Human

Isotype:
IgG1 κ