N24790APCY7

Myosin heavy chain 11 Antibody (MYH11/923), Allophycocyanin/Cy7, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 N24790APCY7-Each-of-1 In Stock ₹ 60,448.14

N24790APCY7 - Each of 1

₹ 60,448.14

In Stock

Quantity

1

Base Price: ₹ 60,448.14

GST (18%): ₹ 10,880.665

Total Price: ₹ 71,328.805

Antigen

Myosin heavy chain 11

Classification

Monoclonal

Conjugate

APC-Cyanine7

Formulation

PBS with 0.05% Sodium Azide

Gene Symbols

MYH11

Immunogen

Recombinant full-length human Myosin heavy chain 11 protein (Uniprot: P35749)

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.

Content And Storage

Store at 4°C in the dark. Do not freeze.

Applications

Flow Cytometry

Clone

MYH11/923

Dilution

Flow Cytometry

Gene Alias

AAT4, FAA4, MYH11, MYH11 myosin, heavy chain 11, smooth muscle, SMHC, SMMHC, Smooth muscle myosin heavy chain

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Hypoxia, Stem Cell Markers

Gene ID (Entrez)

4629.0

Target Species

Human, Rat

Isotype

IgG1 κ

Description

  • Myosin heavy chain 11 Monoclonal specifically detects Myosin heavy chain 11 in Human, Rat samples
  • It is validated for Flow Cytometry.

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Novus Biologicals

N24790APCY7

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Antigen:
Myosin heavy chain 11

Classification:
Monoclonal

Conjugate:
APC-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
MYH11

Immunogen:
Recombinant full-length human Myosin heavy chain 11 protein (Uniprot: P35749)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
MYH11/923

Dilution:
Flow Cytometry

Gene Alias:
AAT4, FAA4, MYH11, MYH11 myosin, heavy chain 11, smooth muscle, SMHC, SMMHC, Smooth muscle myosin heavy chain

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Hypoxia, Stem Cell Markers

Gene ID (Entrez):
4629.0

Target Species:
Human, Rat

Isotype:
IgG1 κ

Img

Novus Biologicals

N247911PEC5

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Antigen:
CD34

Classification:
Monoclonal

Conjugate:
PE-Cyanine5.5

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
CD34

Immunogen:
Recombinant full-length human CD34 protein (Uniprot: P28906)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes a carbohydrate epitope on a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34 (VI international workshop on human differentiation antigens). Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but shows low specificity.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
HPCA1/1171

Dilution:
Flow Cytometry

Gene Alias:
CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Adaptive Immunity, Angiogenesis, B Cell Development and Differentiation Markers, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Hypoxia, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Tumor Suppressors

Gene ID (Entrez):
947.0

Target Species:
Human, Rat

Isotype:
IgG1 κ

Img

Novus Biologicals

N247911PEC7

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Antigen:
CD34

Classification:
Monoclonal

Conjugate:
PE-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
CD34

Immunogen:
Recombinant full-length human CD34 protein (Uniprot: P28906)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes a carbohydrate epitope on a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34 (VI international workshop on human differentiation antigens). Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but shows low specificity.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
HPCA1/1171

Dilution:
Flow Cytometry

Gene Alias:
CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Adaptive Immunity, Angiogenesis, B Cell Development and Differentiation Markers, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Hypoxia, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Tumor Suppressors

Gene ID (Entrez):
947.0

Target Species:
Human, Rat

Isotype:
IgG1 κ

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Novus Biologicals

N247916PEC5

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Antigen:
Moesin

Classification:
Monoclonal

Conjugate:
PE-Cyanine5.5

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
MSN

Immunogen:
Recombinant full-length human Moesin protein (Uniprot: P26038 )

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes 78kDa moesin protein. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the sub-membranous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry, Immunoassay

Clone:
MSN/492

Dilution:
Flow Cytometry, Knockout Validated

Gene Alias:
Membrane-organizing extension spike protein, moesin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Cytoskeleton Markers, Stem Cell Markers

Gene ID (Entrez):
4478.0

Target Species:
Human, Rat (Negative)

Isotype:
IgG1 κ