N247927P594

Transglutaminase 2/TGM2 Antibody (SPM358), PE/Atto594, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 N247927P594-Each-of-1 In Stock ₹ 60,448.14

N247927P594 - Each of 1

₹ 60,448.14

In Stock

Quantity

1

Base Price: ₹ 60,448.14

GST (18%): ₹ 10,880.665

Total Price: ₹ 71,328.805

Antigen

Transglutaminase 2/TGM2

Classification

Monoclonal

Conjugate

PE/ATTO 594

Formulation

PBS with 0.05% Sodium Azide

Gene Symbols

TGM2

Immunogen

Recombinant full-length human Transglutaminase 2/TGM2 protein (Uniprot: P21980)

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

Recognizes a 77-85kDa protein, identified as cellular or tissue transglutaminase II (TGase II). Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD), a genetic, immunologically mediated small bowel enteropathy that causes malabsorption. TGase II is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound he

Content And Storage

Store at 4°C in the dark. Do not freeze.

Applications

Flow Cytometry

Clone

SPM358

Dilution

Flow Cytometry

Gene Alias

C polypeptide, EC 2.3.2.13, G-ALPHA-h, protein-glutamine gamma-glutamyltransferase 2, protein-glutamine-gamma-glutamyltransferase, TG(C), TG2, TGase C, TGase H, TGase-2, TGase-H, TGCGNAH, Tissue transglutaminase, transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase), Transglutaminase C, Transglutaminase H, Transglutaminase-2

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Apoptosis, Immune System Diseases, Immunology, Signal Transduction

Gene ID (Entrez)

7052.0

Target Species

Human, Mouse, Rat, Monkey, Rabbit

Isotype

IgG1 κ

Description

  • Transglutaminase 2/TGM2 Monoclonal specifically detects Transglutaminase 2/TGM2 in Human, Mouse, Rat, Monkey, Rabbit samples
  • It is validated for Flow Cytometry.

Compare Similar Items

Show Difference

Img

Novus Biologicals

N247927P594

--


Antigen:
Transglutaminase 2/TGM2

Classification:
Monoclonal

Conjugate:
PE/ATTO 594

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
TGM2

Immunogen:
Recombinant full-length human Transglutaminase 2/TGM2 protein (Uniprot: P21980)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes a 77-85kDa protein, identified as cellular or tissue transglutaminase II (TGase II). Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD), a genetic, immunologically mediated small bowel enteropathy that causes malabsorption. TGase II is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound he

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
SPM358

Dilution:
Flow Cytometry

Gene Alias:
C polypeptide, EC 2.3.2.13, G-ALPHA-h, protein-glutamine gamma-glutamyltransferase 2, protein-glutamine-gamma-glutamyltransferase, TG(C), TG2, TGase C, TGase H, TGase-2, TGase-H, TGCGNAH, Tissue transglutaminase, transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase), Transglutaminase C, Transglutaminase H, Transglutaminase-2

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Apoptosis, Immune System Diseases, Immunology, Signal Transduction

Gene ID (Entrez):
7052.0

Target Species:
Human, Mouse, Rat, Monkey, Rabbit

Isotype:
IgG1 κ

Img

Novus Biologicals

N247933APC7

--


Antigen:
G-CSF

Classification:
Monoclonal

Conjugate:
APC-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
CSF3

Immunogen:
Nuclei from pokeweed mitogen stimulated human peripheral blood lymphocytes

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody recognizes granulocyte-colony stimulating factor (G-CSF) in the cytoplasm of mature granulocytes. It shows no reactivity with any other cell types. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. It reacts with early precursor and mature forms of myeloid cells. It is useful for the detection of myeloid leukemias and granulocytic sarcomas. It can be used as a marker of granulocytes in normal tissues or inflammatory processes.G-CSF is a pleiotropic cytokine that influences differentiation, proliferation and activation of the neutrophilic granulocyte lineage. The human G-CSF cDNA encodes a 207 amino acid precursor containing a 29 amino acid signal peptide that is proteolytically cleaved to form a 178 amino acid residue mature protein. Two G-CSFs share 73% sequence identity at the amino acid level.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
SPM468

Dilution:
Flow Cytometry

Gene Alias:
C17orf33, chromosome 17 open reading frame 33, colony stimulating factor 3 (granulocyte), CSF3OS, filgrastim, G-CSF, GCSFlenograstim, granulocyte colony-stimulating factor, Lenograstim, MGC45931, pluripoietin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Biologically Active Proteins, Cell Cycle and Replication, Cytokine Research

Gene ID (Entrez):
1440.0

Target Species:
Human, Monkey

Isotype:
IgG1 κ

Img

Novus Biologicals

N247933P594

--


Antigen:
G-CSF

Classification:
Monoclonal

Conjugate:
PE/ATTO 594

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
CSF3

Immunogen:
Nuclei from pokeweed mitogen stimulated human peripheral blood lymphocytes

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody recognizes granulocyte-colony stimulating factor (G-CSF) in the cytoplasm of mature granulocytes. It shows no reactivity with any other cell types. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. It reacts with early precursor and mature forms of myeloid cells. It is useful for the detection of myeloid leukemias and granulocytic sarcomas. It can be used as a marker of granulocytes in normal tissues or inflammatory processes.G-CSF is a pleiotropic cytokine that influences differentiation, proliferation and activation of the neutrophilic granulocyte lineage. The human G-CSF cDNA encodes a 207 amino acid precursor containing a 29 amino acid signal peptide that is proteolytically cleaved to form a 178 amino acid residue mature protein. Two G-CSFs share 73% sequence identity at the amino acid level.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
SPM468

Dilution:
Flow Cytometry

Gene Alias:
C17orf33, chromosome 17 open reading frame 33, colony stimulating factor 3 (granulocyte), CSF3OS, filgrastim, G-CSF, GCSFlenograstim, granulocyte colony-stimulating factor, Lenograstim, MGC45931, pluripoietin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Biologically Active Proteins, Cell Cycle and Replication, Cytokine Research

Gene ID (Entrez):
1440.0

Target Species:
Human, Monkey

Isotype:
IgG1 κ

Img

Novus Biologicals

N247933PEC7

--


Antigen:
G-CSF

Classification:
Monoclonal

Conjugate:
PE-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
CSF3

Immunogen:
Nuclei from pokeweed mitogen stimulated human peripheral blood lymphocytes

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody recognizes granulocyte-colony stimulating factor (G-CSF) in the cytoplasm of mature granulocytes. It shows no reactivity with any other cell types. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. It reacts with early precursor and mature forms of myeloid cells. It is useful for the detection of myeloid leukemias and granulocytic sarcomas. It can be used as a marker of granulocytes in normal tissues or inflammatory processes.G-CSF is a pleiotropic cytokine that influences differentiation, proliferation and activation of the neutrophilic granulocyte lineage. The human G-CSF cDNA encodes a 207 amino acid precursor containing a 29 amino acid signal peptide that is proteolytically cleaved to form a 178 amino acid residue mature protein. Two G-CSFs share 73% sequence identity at the amino acid level.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
SPM468

Dilution:
Flow Cytometry

Gene Alias:
C17orf33, chromosome 17 open reading frame 33, colony stimulating factor 3 (granulocyte), CSF3OS, filgrastim, G-CSF, GCSFlenograstim, granulocyte colony-stimulating factor, Lenograstim, MGC45931, pluripoietin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Biologically Active Proteins, Cell Cycle and Replication, Cytokine Research

Gene ID (Entrez):
1440.0

Target Species:
Human, Monkey

Isotype:
IgG1 κ