N24795PE594

Fc gamma RIII (CD16) Antibody (ICO-116), PE/Atto594, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 N24795PE594-Each-of-1 In Stock ₹ 60,448.14

N24795PE594 - Each of 1

₹ 60,448.14

In Stock

Quantity

1

Base Price: ₹ 60,448.14

GST (18%): ₹ 10,880.665

Total Price: ₹ 71,328.805

Antigen

Fc gamma RIIIA/CD16a

Classification

Monoclonal

Conjugate

PE/ATTO 594

Formulation

PBS with 0.05% Sodium Azide

Gene Symbols

FCGR3A

Immunogen

Human Fc gamma RIII (CD16) protein (Uniprot: P08637)

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

It recognizes CD16 (Fcgamma RIII), the low-affinity receptor for IgG with an apparent molecular weight of 50-80kDa. Two similar genes represent CD16, CD16A (Fcgamma RIIIA), which exists as a hetero-oligomeric polypeptide-anchored form in macrophages and NK cells and CD16B (Fcgamma RIIIB), which exist as a monomeric GPI-anchored form in neutrophils. Furthermore, there are two known polymorphisms of CD16B, NA-1 and NA-2. Individuals homozygous for NA-2 show a lower phagocytic capacity compared with NA-1. CD16 binds IgG in the form of immune complexes and shows preferential binding of IgG1 and IgG3 isotypes and minimal binding of IgG2 and IgG4. Upon IgG binding, both CD16 isoforms initiate signal transduction cascades that lead to a variety of responses including antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, degranulation and proliferation.

Content And Storage

Store at 4°C in the dark. Do not freeze.

Applications

Flow Cytometry

Clone

ICO-116

Dilution

Flow Cytometry

Gene Alias

CD16a, CD16a antigen, CD16FCRIIIA, Fc fragment of IgG, low affinity IIIa, receptor (CD16a), Fc fragment of IgG, low affinity IIIa, receptor for (CD16), Fc gamma receptor III-A, FCG3, Fc-gamma receptor III-2 (CD 16), Fc-gamma receptor IIIb (CD16), Fc-gamma RIII, Fc-gamma RIIIa, Fc-gamma RIII-alpha, FCGR3, FCGRIII, FCR-10, FcRIII, FcRIIIa, IGFR3FcgammaRIIIA, immunoglobulin G Fc receptor III, low affinity III, receptor for (CD16), low affinity immunoglobulin gamma Fc region receptor III-A, neutrophil-specific antigen NA

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Cell Biology, Cellular Markers, Cytokine Research, Growth and Development, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Stem Cells

Gene ID (Entrez)

2214.0

Target Species

Human

Isotype

IgG1 κ

Related Products

Img

Novus Biologicals

NBP128445

--

Img

Novus Biologicals

NBP128446

--

Img

Novus Biologicals

NB10065338V

--

Img

Novus Biologicals

NB001566

--

Img

Novus Biologicals

NBP233321W

--

Img

Novus Biologicals

NBP233321G

--

Img

Novus Biologicals

N247933PEC7

--

Img

Novus Biologicals

N247741P594

--

Description

  • Fc gamma RIII (CD16) Monoclonal specifically detects Fc gamma RIII (CD16) in Human samples
  • It is validated for Flow Cytometry.

Compare Similar Items

Show Difference

Img

Novus Biologicals

N24795PE594

--


Antigen:
Fc gamma RIIIA/CD16a

Classification:
Monoclonal

Conjugate:
PE/ATTO 594

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
FCGR3A

Immunogen:
Human Fc gamma RIII (CD16) protein (Uniprot: P08637)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
It recognizes CD16 (Fcgamma RIII), the low-affinity receptor for IgG with an apparent molecular weight of 50-80kDa. Two similar genes represent CD16, CD16A (Fcgamma RIIIA), which exists as a hetero-oligomeric polypeptide-anchored form in macrophages and NK cells and CD16B (Fcgamma RIIIB), which exist as a monomeric GPI-anchored form in neutrophils. Furthermore, there are two known polymorphisms of CD16B, NA-1 and NA-2. Individuals homozygous for NA-2 show a lower phagocytic capacity compared with NA-1. CD16 binds IgG in the form of immune complexes and shows preferential binding of IgG1 and IgG3 isotypes and minimal binding of IgG2 and IgG4. Upon IgG binding, both CD16 isoforms initiate signal transduction cascades that lead to a variety of responses including antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, degranulation and proliferation.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
ICO-116

Dilution:
Flow Cytometry

Gene Alias:
CD16a, CD16a antigen, CD16FCRIIIA, Fc fragment of IgG, low affinity IIIa, receptor (CD16a), Fc fragment of IgG, low affinity IIIa, receptor for (CD16), Fc gamma receptor III-A, FCG3, Fc-gamma receptor III-2 (CD 16), Fc-gamma receptor IIIb (CD16), Fc-gamma RIII, Fc-gamma RIIIa, Fc-gamma RIII-alpha, FCGR3, FCGRIII, FCR-10, FcRIII, FcRIIIa, IGFR3FcgammaRIIIA, immunoglobulin G Fc receptor III, low affinity III, receptor for (CD16), low affinity immunoglobulin gamma Fc region receptor III-A, neutrophil-specific antigen NA

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Cell Biology, Cellular Markers, Cytokine Research, Growth and Development, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Stem Cells

Gene ID (Entrez):
2214.0

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

N24795PECY5

--


Antigen:
Fc gamma RIIIA/CD16a

Classification:
Monoclonal

Conjugate:
PE-Cyanine5.5

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
FCGR3A

Immunogen:
Human Fc gamma RIII (CD16) protein (Uniprot: P08637)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
It recognizes CD16 (Fcgamma RIII), the low-affinity receptor for IgG with an apparent molecular weight of 50-80kDa. Two similar genes represent CD16, CD16A (Fcgamma RIIIA), which exists as a hetero-oligomeric polypeptide-anchored form in macrophages and NK cells and CD16B (Fcgamma RIIIB), which exist as a monomeric GPI-anchored form in neutrophils. Furthermore, there are two known polymorphisms of CD16B, NA-1 and NA-2. Individuals homozygous for NA-2 show a lower phagocytic capacity compared with NA-1. CD16 binds IgG in the form of immune complexes and shows preferential binding of IgG1 and IgG3 isotypes and minimal binding of IgG2 and IgG4. Upon IgG binding, both CD16 isoforms initiate signal transduction cascades that lead to a variety of responses including antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, degranulation and proliferation.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
ICO-116

Dilution:
Flow Cytometry

Gene Alias:
CD16a, CD16a antigen, CD16FCRIIIA, Fc fragment of IgG, low affinity IIIa, receptor (CD16a), Fc fragment of IgG, low affinity IIIa, receptor for (CD16), Fc gamma receptor III-A, FCG3, Fc-gamma receptor III-2 (CD 16), Fc-gamma receptor IIIb (CD16), Fc-gamma RIII, Fc-gamma RIIIa, Fc-gamma RIII-alpha, FCGR3, FCGRIII, FCR-10, FcRIII, FcRIIIa, IGFR3FcgammaRIIIA, immunoglobulin G Fc receptor III, low affinity III, receptor for (CD16), low affinity immunoglobulin gamma Fc region receptor III-A, neutrophil-specific antigen NA

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Cell Biology, Cellular Markers, Cytokine Research, Growth and Development, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Stem Cells

Gene ID (Entrez):
2214.0

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

N247961APC7

--


Antigen:
Neprilysin/CD10

Classification:
Monoclonal

Conjugate:
APC-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
MME

Immunogen:
Human Neprilysin/CD10 (Uniprot: P08473)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes a 100kDa glycoprotein, identified as CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt′s, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
CB-CALLA

Dilution:
Flow Cytometry

Gene Alias:
Atriopeptidase, CALLAmembrane metallo-endopeptidase (neutral endopeptidase, enkephalinase), CD10 antigen, CD10), CD10membrane metallo-endopeptidase variant 1, Common acute lymphocytic leukemia antigen, DKFZp686O16152, EC 3.4.24, EC 3.4.24.11, Enkephalinase, EPN, membrane metallo-endopeptidase, membrane metallo-endopeptidase variant 2, MGC126681, MGC126707, NEPmembrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, neprilysin, Neutral endopeptidase, Neutral endopeptidase 24.11, SFE, Skin fibroblast elastase

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
B Cell Development and Differentiation Markers, Cancer, Cell Biology, Cytokine Research, Immunology, Stem Cell Markers

Gene ID (Entrez):
4311.0

Target Species:
Human

Isotype:
IgG2b κ

Img

Novus Biologicals

N247961P594

--


Antigen:
Neprilysin/CD10

Classification:
Monoclonal

Conjugate:
PE/ATTO 594

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
MME

Immunogen:
Human Neprilysin/CD10 (Uniprot: P08473)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes a 100kDa glycoprotein, identified as CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt′s, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
CB-CALLA

Dilution:
Flow Cytometry

Gene Alias:
Atriopeptidase, CALLAmembrane metallo-endopeptidase (neutral endopeptidase, enkephalinase), CD10 antigen, CD10), CD10membrane metallo-endopeptidase variant 1, Common acute lymphocytic leukemia antigen, DKFZp686O16152, EC 3.4.24, EC 3.4.24.11, Enkephalinase, EPN, membrane metallo-endopeptidase, membrane metallo-endopeptidase variant 2, MGC126681, MGC126707, NEPmembrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, neprilysin, Neutral endopeptidase, Neutral endopeptidase 24.11, SFE, Skin fibroblast elastase

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
B Cell Development and Differentiation Markers, Cancer, Cell Biology, Cytokine Research, Immunology, Stem Cell Markers

Gene ID (Entrez):
4311.0

Target Species:
Human

Isotype:
IgG2b κ