N247993PEC7
Alkaline Phosphatase/ALPP Antibody (PL8-F6), PE/Cy7, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | N247993PEC7-Each-of-1 | In Stock | ₹ 60,448.14 |
N247993PEC7 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 60,448.14
GST (18%): ₹ 10,880.665
Total Price: ₹ 71,328.805
Antigen
Alkaline Phosphatase/ALPP
Classification
Monoclonal
Conjugate
PE-Cyanine7
Formulation
PBS with 0.05% Sodium Azide
Gene Symbols
ALPP
Immunogen
Purified human Alkaline Phosphatase/ALPP protein (Uniprot: P05187)
Quantity
0.1 mL
Primary or Secondary
Primary
Test Specificity
Reacts with a 70kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP reacts with germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease.
Content And Storage
Store at 4°C in the dark. Do not freeze.
Applications
Flow Cytometry
Clone
PL8-F6
Dilution
Flow Cytometry
Gene Alias
Alkaline phosphatase Regan isozyme, alkaline phosphatase, placental, alkaline phosphatase, placental (Regan isozyme), alkaline phosphatase, placental type, alkaline phosphomonoesterase, ALP, EC 3.1.3.1, FLJ61142, glycerophosphatase, PALP, Placental alkaline phosphatase 1, PLAP, PLAP-1, Regan isozyme
Host Species
Mouse
Purification Method
Protein A or G purified
Research Discipline
Cancer, Embryonic Stem Cell Markers, Ovarian Carcinoma Cell Markers, Phospho Specific, Stem Cell Markers
Gene ID (Entrez)
250.0
Target Species
Human
Isotype
IgG2b κ
Description
- Alkaline Phosphatase/ALPP Monoclonal specifically detects Alkaline Phosphatase/ALPP in Human samples
- It is validated for Flow Cytometry.
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Antigen: Alkaline Phosphatase/ALPP
Classification: Monoclonal
Conjugate: PE-Cyanine7
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: ALPP
Immunogen: Purified human Alkaline Phosphatase/ALPP protein (Uniprot: P05187)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Reacts with a 70kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP reacts with germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease.
Content And Storage: Store at 4°C in the dark. Do not freeze.
Applications: Flow Cytometry
Clone: PL8-F6
Dilution: Flow Cytometry
Gene Alias: Alkaline phosphatase Regan isozyme, alkaline phosphatase, placental, alkaline phosphatase, placental (Regan isozyme), alkaline phosphatase, placental type, alkaline phosphomonoesterase, ALP, EC 3.1.3.1, FLJ61142, glycerophosphatase, PALP, Placental alkaline phosphatase 1, PLAP, PLAP-1, Regan isozyme
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Cancer, Embryonic Stem Cell Markers, Ovarian Carcinoma Cell Markers, Phospho Specific, Stem Cell Markers
Gene ID (Entrez): 250.0
Target Species: Human
Isotype: IgG2b κ
Antigen:
Alkaline Phosphatase/ALPP
Classification:
Monoclonal
Conjugate:
PE-Cyanine7
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
ALPP
Immunogen:
Purified human Alkaline Phosphatase/ALPP protein (Uniprot: P05187)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Reacts with a 70kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP reacts with germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease.
Content And Storage:
Store at 4°C in the dark. Do not freeze.
Applications:
Flow Cytometry
Clone:
PL8-F6
Dilution:
Flow Cytometry
Gene Alias:
Alkaline phosphatase Regan isozyme, alkaline phosphatase, placental, alkaline phosphatase, placental (Regan isozyme), alkaline phosphatase, placental type, alkaline phosphomonoesterase, ALP, EC 3.1.3.1, FLJ61142, glycerophosphatase, PALP, Placental alkaline phosphatase 1, PLAP, PLAP-1, Regan isozyme
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Cancer, Embryonic Stem Cell Markers, Ovarian Carcinoma Cell Markers, Phospho Specific, Stem Cell Markers
Gene ID (Entrez):
250.0
Target Species:
Human
Isotype:
IgG2b κ
Antigen: Alkaline Phosphatase, Tissue Non-Specific
Classification: Monoclonal
Conjugate: APC-Cyanine7
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: ALPL
Immunogen: Bovine alkaline phosphatase (Uniprot: P05186)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively sp
Content And Storage: Store at 4°C in the dark. Do not freeze.
Applications: Flow Cytometry
Clone: V17.1
Dilution: Flow Cytometry
Gene Alias: Alkaline phosphatase liver/bone/kidney isozyme, alkaline phosphatase, liver/bone/kidney, alkaline phosphatase, tissue-nonspecific isozyme, alkaline phosphomonoesterase, APTNAP, AP-TNAP, EC 3.1.3.1, FLJ40094, FLJ93059, glycerophosphatase, HOPS, liver/bone/kidney-type alkaline phosphatase, MGC161443, tissue-nonspecific ALP, TNAP, TNSALPMGC167935
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Cancer, Embryonic Stem Cell Markers, Lipid and Metabolism, Protein Phosphatase, Stem Cell Markers
Gene ID (Entrez): 249.0
Target Species: Human, Primate
Isotype: IgG1 κ
Antigen:
Alkaline Phosphatase, Tissue Non-Specific
Classification:
Monoclonal
Conjugate:
APC-Cyanine7
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
ALPL
Immunogen:
Bovine alkaline phosphatase (Uniprot: P05186)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively sp
Content And Storage:
Store at 4°C in the dark. Do not freeze.
Applications:
Flow Cytometry
Clone:
V17.1
Dilution:
Flow Cytometry
Gene Alias:
Alkaline phosphatase liver/bone/kidney isozyme, alkaline phosphatase, liver/bone/kidney, alkaline phosphatase, tissue-nonspecific isozyme, alkaline phosphomonoesterase, APTNAP, AP-TNAP, EC 3.1.3.1, FLJ40094, FLJ93059, glycerophosphatase, HOPS, liver/bone/kidney-type alkaline phosphatase, MGC161443, tissue-nonspecific ALP, TNAP, TNSALPMGC167935
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Cancer, Embryonic Stem Cell Markers, Lipid and Metabolism, Protein Phosphatase, Stem Cell Markers
Gene ID (Entrez):
249.0
Target Species:
Human, Primate
Isotype:
IgG1 κ
Antigen: Alkaline Phosphatase, Tissue Non-Specific
Classification: Monoclonal
Conjugate: PE-Cyanine5.5
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: ALPL
Immunogen: Bovine alkaline phosphatase (Uniprot: P05186)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively sp
Content And Storage: Store at 4°C in the dark. Do not freeze.
Applications: Flow Cytometry
Clone: V17.1
Dilution: Flow Cytometry
Gene Alias: Alkaline phosphatase liver/bone/kidney isozyme, alkaline phosphatase, liver/bone/kidney, alkaline phosphatase, tissue-nonspecific isozyme, alkaline phosphomonoesterase, APTNAP, AP-TNAP, EC 3.1.3.1, FLJ40094, FLJ93059, glycerophosphatase, HOPS, liver/bone/kidney-type alkaline phosphatase, MGC161443, tissue-nonspecific ALP, TNAP, TNSALPMGC167935
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Cancer, Embryonic Stem Cell Markers, Lipid and Metabolism, Protein Phosphatase, Stem Cell Markers
Gene ID (Entrez): 249.0
Target Species: Human, Primate
Isotype: IgG1 κ
Antigen:
Alkaline Phosphatase, Tissue Non-Specific
Classification:
Monoclonal
Conjugate:
PE-Cyanine5.5
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
ALPL
Immunogen:
Bovine alkaline phosphatase (Uniprot: P05186)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively sp
Content And Storage:
Store at 4°C in the dark. Do not freeze.
Applications:
Flow Cytometry
Clone:
V17.1
Dilution:
Flow Cytometry
Gene Alias:
Alkaline phosphatase liver/bone/kidney isozyme, alkaline phosphatase, liver/bone/kidney, alkaline phosphatase, tissue-nonspecific isozyme, alkaline phosphomonoesterase, APTNAP, AP-TNAP, EC 3.1.3.1, FLJ40094, FLJ93059, glycerophosphatase, HOPS, liver/bone/kidney-type alkaline phosphatase, MGC161443, tissue-nonspecific ALP, TNAP, TNSALPMGC167935
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Cancer, Embryonic Stem Cell Markers, Lipid and Metabolism, Protein Phosphatase, Stem Cell Markers
Gene ID (Entrez):
249.0
Target Species:
Human, Primate
Isotype:
IgG1 κ
Antigen: Fibronectin
Classification: Monoclonal
Conjugate: PE/ATTO 594
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: FN1
Immunogen: High molecular weight proteins secreted by cultivated human fibroblasts (Uniprot: P02751)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Epitope of this monoclonal antibody is located in the 8th type III repeat in the cell-binding region of fibronectin. Fibronectins are disulfide-linked, dimeric glycoproteins of ∼440kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Fibronectins are involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This monoclonal antibody is excellent for staining of formalin-fixed, paraffin-embedded tissues.
Content And Storage: Store at 4°C in the dark. Do not freeze.
Applications: Flow Cytometry
Clone: 568
Dilution: Flow Cytometry
Gene Alias: CIG, ED-B, fibronectin 1, FINC, FN, FN1, FNZ, GFND, GFND2, LETS, MSF, SMDCF
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Cancer, Cellular Markers, Extracellular Matrix, Mesenchymal Stem Cell Markers, Neuronal Stem Cell Markers, Stem Cell Markers
Gene ID (Entrez): 2335.0
Target Species: Human
Isotype: IgG1 κ
Antigen:
Fibronectin
Classification:
Monoclonal
Conjugate:
PE/ATTO 594
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
FN1
Immunogen:
High molecular weight proteins secreted by cultivated human fibroblasts (Uniprot: P02751)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Epitope of this monoclonal antibody is located in the 8th type III repeat in the cell-binding region of fibronectin. Fibronectins are disulfide-linked, dimeric glycoproteins of ∼440kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Fibronectins are involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This monoclonal antibody is excellent for staining of formalin-fixed, paraffin-embedded tissues.
Content And Storage:
Store at 4°C in the dark. Do not freeze.
Applications:
Flow Cytometry
Clone:
568
Dilution:
Flow Cytometry
Gene Alias:
CIG, ED-B, fibronectin 1, FINC, FN, FN1, FNZ, GFND, GFND2, LETS, MSF, SMDCF
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Cancer, Cellular Markers, Extracellular Matrix, Mesenchymal Stem Cell Markers, Neuronal Stem Cell Markers, Stem Cell Markers
Gene ID (Entrez):
2335.0
Target Species:
Human
Isotype:
IgG1 κ